{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:13:03Z","timestamp":1780103583823,"version":"3.54.0"},"reference-count":79,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,3,6]],"date-time":"2015-03-06T00:00:00Z","timestamp":1425600000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100011054","name":"Danish International Development Agency","doi-asserted-by":"crossref","award":["66-08-LIFE"],"award-info":[{"award-number":["66-08-LIFE"]}],"id":[{"id":"10.13039\/501100011054","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The genus<jats:italic>Campylobacter<\/jats:italic>comprises members known to be a leading cause of foodborne gastrointestinal illness worldwide. A study was conducted to determine the epidemiology and antimicrobial resistance of<jats:italic>Campylobacter<\/jats:italic>in humans in Morogoro, Eastern Tanzania. Isolation of<jats:italic>Campylobacter<\/jats:italic>from stool specimens adopted the Cape Town protocol.<jats:italic>Campylobacter<\/jats:italic>isolates were preliminarily identified by conventional phenotypic tests and subsequently confirmed by matrix\u2010assisted laser desorption\/ionization\u2013time\u2010of\u2010flight (<jats:styled-content style=\"fixed-case\">MALDI<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TOF<\/jats:styled-content>) mass spectrometry and polymerase chain reaction. Antimicrobial resistance testing employed the disc diffusion method. A small proportion of the test isolates was also subjected to agar dilution method. Risk factors for human illness were determined in an unmatched case\u2013control study. Thermophilic<jats:italic>Campylobacter<\/jats:italic>were isolated from 11.4% of the screened individuals (<jats:italic>n<\/jats:italic>\u00a0=\u00a01195). The agreement between<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">MALDI<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TOF<\/jats:styled-content>was perfect (\u03ba\u00a0=\u00a01.0). Symptomatics and young individuals were infected with higher numbers than asymptomatic and adults, respectively. The majority (84.6%) of the isolates were<jats:italic>C.\u00a0jejuni<\/jats:italic>and the remaining were<jats:italic>C.\u00a0coli<\/jats:italic>. Isolates had highest resistance (95.6%) for colistin sulphate and lowest for ciprofloxacin (22.1%). The rates of resistance for other antibiotics (azithromycin, erythromycin, tetracycline, cephalothin, gentamycin, nalidixic acid, ampicillin, amoxycillin, norfloxacin, chloramphenicol) ranged from 44.1% to 89%. Comparison between disc diffusion and agar dilution methods indicated a good correlation, and the tests were in agreement to each other (\u03ba\u00a0\u2265\u00a00.75). Human illness was found to be associated with young age and consumption of chicken meat and pre\u2010prepared salad. Our data indicate the presence of antibiotic\u2010resistant thermophilic<jats:italic>Campylobacter<\/jats:italic>in humans in the study area. There is a need for routine investigation of the presence of the\u00a0organisms in gastroenteritis aetiology, including determination of their antibiotic susceptibilities.<\/jats:p>","DOI":"10.1111\/zph.12185","type":"journal-article","created":{"date-parts":[[2015,3,6]],"date-time":"2015-03-06T09:29:12Z","timestamp":1425634152000},"page":"557-568","source":"Crossref","is-referenced-by-count":41,"title":["Prevalence, Antimicrobial Resistance and Risk Factors for Thermophilic<i>Campylobacter<\/i>Infections in Symptomatic and Asymptomatic Humans in Tanzania"],"prefix":"10.1111","volume":"62","author":[{"given":"E. V. G.","family":"Komba","sequence":"first","affiliation":[{"name":"Department of Veterinary Medicine and Public Health Faculty of Veterinary Medicine Sokoine University of Agriculture Morogoro Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. H.","family":"Mdegela","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Public Health Faculty of Veterinary Medicine Sokoine University of Agriculture Morogoro Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. L. M.","family":"Msoffe","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Public Health Faculty of Veterinary Medicine Sokoine University of Agriculture Morogoro Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. 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