{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:24:31Z","timestamp":1792805071982,"version":"4.5.0"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,4,27]],"date-time":"2015-04-27T00:00:00Z","timestamp":1430092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"University of Helsinki, Doctoral Programme of Food Chain and Health"},{"name":"Walter Ehrstr\u00f6m Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Antimicrobial susceptibility was determined for 805 domestic <jats:italic>Campylobacter jejuni<\/jats:italic> isolates obtained from broilers (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>459), bovines (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>120), human patients (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>95), natural waters (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>80), wild birds (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>35) and zoo animals\/enclosures (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>16) with known multilocus sequence types (<jats:styled-content style=\"fixed-case\">MLST<\/jats:styled-content>) for 450 isolates. The minimum inhibitory concentration (<jats:styled-content style=\"fixed-case\">MIC<\/jats:styled-content>) values for erythromycin, tetracycline, streptomycin, gentamicin and the quinolones ciprofloxacin and nalidixic acid were determined with the Vet<jats:styled-content style=\"fixed-case\">MIC<\/jats:styled-content> method. <jats:styled-content style=\"fixed-case\">MIC<\/jats:styled-content>s were compared with <jats:styled-content style=\"fixed-case\">MLST<\/jats:styled-content> types to find possible associations between sequence type and resistance. The proportions of resistant isolates were 5% (broilers), 6.3% (natural waters), 11.4% (wild birds), 11.6% (human patients), 16.7% (bovines) and 31.3% (zoo). The most common resistance among the human and bovine isolates was quinolone resistance alone while resistance to streptomycin alone was most often detected among the broiler isolates and tetracycline resistance was most commonly observed in the wild bird, water and zoo isolates. No or negligible resistance to erythromycin or gentamicin was detected. In all data, 12\/26 of the tetracycline\u2010resistant isolates were also resistant to streptomycin (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001) and the clonal complex (<jats:styled-content style=\"fixed-case\">CC<\/jats:styled-content>) <jats:styled-content style=\"fixed-case\">ST<\/jats:styled-content>\u20101034 <jats:styled-content style=\"fixed-case\">CC<\/jats:styled-content> showed a high proportion of 75% (9\/12) of tetracycline\u2010resistant isolates, most originating from the zoo and broilers with closely associated <jats:styled-content style=\"fixed-case\">MLST<\/jats:styled-content> types from these sources. No association between quinolone resistance and <jats:styled-content style=\"fixed-case\">MLST<\/jats:styled-content> type was seen. The low percentage of resistant isolates among the domestic <jats:italic>Campylobacter<\/jats:italic> infections is most probably due to the long\u2010term controlled use of antimicrobials. However, the higher percentage of tetracycline resistance observed among the zoo isolates could present a risk for zoo visitors of acquisition of resistant <jats:italic>C.\u00a0jejuni<\/jats:italic>. The resistance pattern of tetracycline and streptomycin most often found in <jats:styled-content style=\"fixed-case\">ST<\/jats:styled-content>\u20101034 <jats:styled-content style=\"fixed-case\">CC<\/jats:styled-content> could indicate a common resistance acquisition mechanism commonly present in this <jats:styled-content style=\"fixed-case\">CC<\/jats:styled-content>. Overall, <jats:styled-content style=\"fixed-case\">MLST<\/jats:styled-content> typing was found to be a useful method in recognition of potential genetic lineages associated with resistance.<\/jats:p>","DOI":"10.1111\/zph.12198","type":"journal-article","created":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T05:28:30Z","timestamp":1430198910000},"page":"10-19","source":"Crossref","is-referenced-by-count":22,"title":["Antimicrobial Resistance and Multilocus Sequence Types of Finnish <i>Campylobacter jejuni<\/i> Isolates from Multiple Sources"],"prefix":"10.1111","volume":"63","author":[{"given":"S.","family":"Olkkola","sequence":"first","affiliation":[{"name":"Department of Food Hygiene and Environmental Health Faculty of Veterinary Medicine University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Nyk\u00e4senoja","sequence":"additional","affiliation":[{"name":"The Finnish Food Safety Authority Evira Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Raulo","sequence":"additional","affiliation":[{"name":"The Finnish Food Safety Authority Evira Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.\u2010K.","family":"Llarena","sequence":"additional","affiliation":[{"name":"Department of Food Hygiene and Environmental Health Faculty of Veterinary Medicine University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Kovanen","sequence":"additional","affiliation":[{"name":"Department of Food Hygiene and Environmental Health Faculty of Veterinary Medicine University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Kivist\u00f6","sequence":"additional","affiliation":[{"name":"Department of Food Hygiene and Environmental Health Faculty of Veterinary Medicine University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.\u2010L.","family":"Myllyniemi","sequence":"additional","affiliation":[{"name":"The Finnish Food Safety Authority Evira Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.\u2010L.","family":"H\u00e4nninen","sequence":"additional","affiliation":[{"name":"Department of Food Hygiene and Environmental Health Faculty of Veterinary Medicine University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,4,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/9781555815554.ch6"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00669-13"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.47103-0"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.106.063305"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2014.3547"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2014.3590"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.71.10.5865-5872.2005"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1757-4749-2-22"},{"key":"e_1_2_8_10_1","unstructured":"Finnish Food Safety Authority Evira 2011:FINRES\u2010Vet 2007\u20102009: Finnish Veterinary Antimicrobial Resistance Monitoring and Consumption of Antimicrobial Agents. Evira publications 1\/2011. Available at:http:\/\/www.evira.fi\/portal\/en\/about+evira\/publications\/?a=category&cid=28(Accessed on 10 October 2014)."},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.8.3347-3354.2005"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-10-200"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1863-2378.2012.01525.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00168-09"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00374-09"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2011.02.008"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jam.12120"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01488-06"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0081796"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00237-09"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01959-14"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.7.2124-2131.2002"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12141"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0116585"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.2217\/17460913.4.2.189"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.1.390-394.2003"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0408966102"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1086\/339195"},{"key":"e_1_2_8_29_1","unstructured":"National Institute of Health and Welfare (THL) 2014:Prevalence of Campylobacters in 2013 (in Finnish). Available at:http:\/\/www.thl.fi\/fi\/web\/infektiotaudit\/seuranta-ja-epidemiat\/tartuntatautirekisteri\/tartuntataudit-suomessa-vuosiraportit\/tautien-esiintyvyys-2013\/kampylobakteerin-esiintyvyys-2013(Accessed on 10 October 2014)."},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.6.2454-2459.2005"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.10050"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.1.102-105.2003"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.3.1086-1088.2006"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2012.0099"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mst197"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.37.3.457"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-13-160"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00813-10"},{"key":"e_1_2_8_39_1","unstructured":"Zoonoses centre 2014:Antimicrobial resistance: Campylobacters (in Finnish). Available at:http:\/\/www.zoonoosikeskus.fi\/portal\/fi\/mikrobilaakeresistenssi\/zoonoosibakteerien_resistenssi\/kampylobakteeri\/(Accessed on 10 October 2014)."}],"container-title":["Zoonoses and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fzph.12198","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/zph.12198","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T15:26:29Z","timestamp":1696173989000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/zph.12198"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,27]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1111\/zph.12198"],"URL":"https:\/\/doi.org\/10.1111\/zph.12198","archive":["Portico"],"relation":{},"ISSN":["1863-1959","1863-2378"],"issn-type":[{"value":"1863-1959","type":"print"},{"value":"1863-2378","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,27]]}}}