{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T10:22:48Z","timestamp":1778494968611,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,2,16]],"date-time":"2017-02-16T00:00:00Z","timestamp":1487203200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2017,11]]},"abstract":"Summary<\/jats:title>Erysipelothrix rhusiopathiae<\/jats:italic> is a facultatively anaerobic Gram\u2010positive bacillus found mostly in swine, fish and sheep. E.\u00a0rhusiopathiae<\/jats:italic> classically causes cutaneous eruptions in butchers, fish handlers and veterinarians. Based solely on case reports, 90% of E.\u00a0rhusiopathiae<\/jats:italic> bloodstream infections (BSI<\/jats:styled-content>) have been associated with infective endocarditis (IE<\/jats:styled-content>). To assess the true frequency of IE<\/jats:styled-content> in E.\u00a0rhusiopathiae <\/jats:italic>BSI<\/jats:styled-content> as well as other clinical associations, we performed a retrospective cohort analysis of E.\u00a0rhusiopathiae <\/jats:italic>BSI<\/jats:styled-content> at Mayo Clinic. This is a single\u2010centre, retrospective study conducted between 1\/1\/1994 and 20\/6\/2016 at Mayo Clinic in Rochester, MN<\/jats:styled-content>. Medical records were reviewed for demographics, E.\u00a0rhusiopathiae <\/jats:italic>BSI<\/jats:styled-content>, anti\u2010microbial susceptibilities, incidence of IE<\/jats:styled-content>, patient comorbidities, intensive care unit (ICU<\/jats:styled-content>) admission and duration of antibiotics. Five cases of E.\u00a0rhusiopathiae <\/jats:italic>BSI<\/jats:styled-content> were identified. Risk factors included animal exposures, immunosuppression, diabetes and kidney disease. All cases involved penicillin\u2010sensitive strains and high\u2010grade BSI<\/jats:styled-content>. Four cases showed no signs of IE<\/jats:styled-content> on transesophageal echocardiogram. All patients recovered fully with intravenous antibiotics. Our retrospective review illustrates that E.\u00a0rhusiopathiae<\/jats:italic> can cause invasive BSI<\/jats:styled-content> in the absence of IE<\/jats:styled-content> and that the previously reported 90% association between BSI<\/jats:styled-content> and IE<\/jats:styled-content> may be overestimated due to reporting bias. E.\u00a0rhusiopathiae<\/jats:italic> should be suspected in any patient with Gram\u2010positive bacilli in blood cultures and the aforementioned risk factors. A limitation of our study was the low sample size, and future studies may involve multicentre collaborations and the use of polymerase chain reaction (PCR<\/jats:styled-content>) or serologic testing to increase the number of diagnoses..<\/jats:p>","DOI":"10.1111\/zph.12348","type":"journal-article","created":{"date-parts":[[2017,2,16]],"date-time":"2017-02-16T10:13:15Z","timestamp":1487239995000},"source":"Crossref","is-referenced-by-count":21,"title":["Erysipelothrix rhusiopathiae<\/i> bloodstream infection \u2013 A 22\u2010year experience at Mayo Clinic, Minnesota"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4141-7155","authenticated-orcid":false,"given":"E. M.","family":"Tan","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Mayo Clinic Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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