{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:49:19Z","timestamp":1788691759969,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,9,14]],"date-time":"2017-09-14T00:00:00Z","timestamp":1505347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Paraguay has registered no human cases of rabies since 2004, and the last case in dogs, reported in 2009, was due to a variant maintained in the common vampire bat \u201c<jats:italic>Desmodus rotundus<\/jats:italic>\u201d. In 2014, a dog was diagnosed as positive for rabies with aggression towards a boy and all required measures of control were successfully adopted. Epidemiological investigation revealed that the dog was not vaccinated and had been attacked by a crab\u2010eating fox, \u201czorro\u201d (<jats:italic>Cerdocyon thous<\/jats:italic>). The sample was diagnosed by the Official Veterinary Service of the Country and sent to the Center on Rabies Research from the University of S\u00e3o Paulo, Brazil, for antigenic and genetic characterization. A second sample from a dog positive for rabies in the same region in 2015 and 11 samples from a rabies outbreak from Asuncion in 1996 were also characterized. The antigenic profile of the samples, AgV2, was compatible with one of the variants maintained by dogs in Latin America. In genetic characterization, the samples segregated in the canine (domestic and wild species)\u2010related group in an independent subgroup that also included samples from Argentina. These results and the epidemiology of the case indicate that even with the control of rabies in domestic animals, the virus can still circulate in wildlife and may be transmitted to domestic animals and humans, demonstrating the importance of continuous and improved surveillance and control of rabies, including in wild species, to prevent outbreaks in controlled areas.<\/jats:p>","DOI":"10.1111\/zph.12392","type":"journal-article","created":{"date-parts":[[2017,9,15]],"date-time":"2017-09-15T04:52:49Z","timestamp":1505451169000},"page":"222-226","source":"Crossref","is-referenced-by-count":13,"title":["Re\u2010emergence of rabies virus maintained by canid populations in Paraguay"],"prefix":"10.1111","volume":"65","author":[{"given":"A. C. F.","family":"Amarilla","sequence":"first","affiliation":[{"name":"Ministry of Public Health and Social Welfare  Asunci\u00f3n Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. C. A.","family":"Pompei","sequence":"additional","affiliation":[{"name":"PANAFTOSA \u2013 PanAmerican Health Organization \u2013 World Health Organization (PAHO\/WHO)  Duque de Caxias RJ Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2987-7466","authenticated-orcid":false,"given":"D. B.","family":"Araujo","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical and Molecular Virology \u2013 Institute of Biomedical Sciences \u2013 University of Sao Paulo  Sao Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. A.","family":"V\u00e1zquez","sequence":"additional","affiliation":[{"name":"Ministry of Public Health and Social Welfare  Asunci\u00f3n Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. R.","family":"Galeano","sequence":"additional","affiliation":[{"name":"Ministry of Public Health and Social Welfare  Asunci\u00f3n Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. M.","family":"Delgado","sequence":"additional","affiliation":[{"name":"Ministry of Public Health and Social Welfare  Asunci\u00f3n Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Bogado","sequence":"additional","affiliation":[{"name":"National Service of Quality and Animal Health \u2013 SENACSA  Asunci\u00f3n Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Colman","sequence":"additional","affiliation":[{"name":"National Service of Quality and Animal Health \u2013 SENACSA  Asunci\u00f3n Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Sanabria","sequence":"additional","affiliation":[{"name":"National Service of Quality and Animal Health \u2013 SENACSA  Asunci\u00f3n Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Iamamoto","sequence":"additional","affiliation":[{"name":"Pasteur Institute of S\u00e3o Paulo  S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Garcia","sequence":"additional","affiliation":[{"name":"PanAmerican Health Organization \u2013 World Health Organization (PAHO\/WHO)  Asunci\u00f3n Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Assis","sequence":"additional","affiliation":[{"name":"PanAmerican Health Organization \u2013 World Health Organization (PAHO\/WHO)  Asunci\u00f3n Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Recalde","sequence":"additional","affiliation":[{"name":"Ministry of Public Health and Social Welfare  Asunci\u00f3n Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. F.","family":"Martorelli","sequence":"additional","affiliation":[{"name":"Center of Zoonosis Control  S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Qui\u00f1ones","sequence":"additional","affiliation":[{"name":"Ministry of Public Health and Social Welfare  Asunci\u00f3n Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Cabello","sequence":"additional","affiliation":[{"name":"Ministry of Public Health and Social Welfare  Asunci\u00f3n Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Martini","sequence":"additional","affiliation":[{"name":"PANAFTOSA \u2013 PanAmerican Health Organization \u2013 World Health Organization (PAHO\/WHO)  Duque de Caxias RJ Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Cosivi","sequence":"additional","affiliation":[{"name":"PANAFTOSA \u2013 PanAmerican Health Organization \u2013 World Health Organization (PAHO\/WHO)  Duque de Caxias RJ Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. L.","family":"Durigon","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical and Molecular Virology \u2013 Institute of Biomedical Sciences \u2013 University of Sao Paulo  Sao Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. R.","family":"Favoretto","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical and Molecular Virology \u2013 Institute of Biomedical Sciences \u2013 University of Sao Paulo  Sao Paulo SP Brazil"},{"name":"Pasteur Institute of S\u00e3o Paulo  S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,14]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Argentina Ministry of Health(2015).Cases of canine rabies in the provinces of Salta and Jujuy. Risk for human health. Retrieved fromhttp:\/\/www.msal.gob.ar\/images\/stories\/epidemiologia\/alertas-2015\/28-04-2015-alerta-rabia-syj.pdf."},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2005.03.006"},{"key":"e_1_2_7_4_1","unstructured":"Bolivia Ministry of Health(2016).Bolivia had no cases of human rabies transmitted by dogs in 2016. Retrieved fromhttps:\/\/www.minsalud.gob.bo\/2059-bolivia-no-registro-casos-de-rabia-humana-transmitida-por-canes-en-la-gestion-2016."},{"key":"e_1_2_7_5_1","unstructured":"Brazil Ministry of Health(2016a).Program for control surveillance and prophylaxis of Rabies. Retrieved fromhttp:\/\/portalsaude.saude.gov.br\/index.php?option=com_content&view=article&id=11057&Itemid=677."},{"key":"e_1_2_7_6_1","unstructured":"Brazil Ministry of Health(2016b).Analysis of the epidemiologic situation of rabies in brazil from 2011 to 2016. Retrieved fromhttp:\/\/portalarquivos.saude.gov.br\/images\/pdf\/2016\/maio\/27\/Informe-epidemiol-gico-raiva.pdf."},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2011.03.030"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2006.02.007"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2004.10.013"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12253"},{"issue":"8","key":"e_1_2_7_11_1","first-page":"477","article-title":"Monoclonal antibody characterization of rabies virus strains isolated in the River Plate Basin","volume":"44","author":"Delpietro H. A.","year":"1997","journal-title":"Zentralblatt f\u00fcr Veterin\u00e4rmedizin"},{"issue":"3","key":"e_1_2_7_12_1","first-page":"153","article-title":"Antigenic analysis of rabies\u2010virus isolates from Latin America and the Caribbean","volume":"41","author":"Diaz A. M.","year":"1994","journal-title":"Zentralblatt f\u00fcr Veterin\u00e4rmedizin"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652002000200007"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1212.060429"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1995.1285"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2007.08.002"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2007.06.008"},{"key":"e_1_2_7_18_1","first-page":"214","article-title":"Temas de actualidad: Los anticuerpos monoclonales en la caracterizaci\u00f3n y vigilancia de los virus de la rabia en Am\u00e9rica latina y el Caribe","volume":"8","author":"Panamerican Health Organization (PAHO)","year":"2002","journal-title":"Revista Panamericana de Salud Publica"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-011-1146-1"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/166.2.296"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1412.080876"},{"key":"e_1_2_7_22_1","unstructured":"World Health Organization(2017).WHO Expert Consultation on Rabies. WHO Technical Report Series 982. Second Report.Geneva:The Organization. Retrieved fromhttp:\/\/apps.who.int\/iris\/handle\/10665\/85346."},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003251"}],"container-title":["Zoonoses and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fzph.12392","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/zph.12392","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T21:30:52Z","timestamp":1694986252000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/zph.12392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,14]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1111\/zph.12392"],"URL":"https:\/\/doi.org\/10.1111\/zph.12392","archive":["Portico"],"relation":{},"ISSN":["1863-1959","1863-2378"],"issn-type":[{"value":"1863-1959","type":"print"},{"value":"1863-2378","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,14]]}}}