{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T08:31:19Z","timestamp":1789893079292,"version":"4.0.1"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,11,7]],"date-time":"2017-11-07T00:00:00Z","timestamp":1510012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"French Ministry of Agriculture"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:label\/><jats:p>Antimicrobial resistance (AMR) among bacteria isolated from food\u2010producing animals is a growing concern with implications for public health. AMR surveillance is essential to identify resistance trends and help in the design of effective and efficient control strategies. The aim of the study was to describe the antimicrobial susceptibility of pathogenic <jats:italic>Escherichia coli<\/jats:italic> isolated from three livestock productions in France (cattle, swine and poultry). The trend in resistance to the most commonly prescribed antibiotics in animal health was analysed as follows: amoxicillin (penicillin), spectinomycin or streptomycin (aminoglycoside), tetracycline and trimethoprim\u2010sulfamethoxazole\/Enrofloxacin and ceftiofur were also taken into account as members of critically important antimicrobial families in human and veterinary medicine, that is fluoroquinolones and third\u2010generation cephalosporins, respectively. Data collected between 2002 and 2015 by the French national surveillance network of AMR referred to as RESAPATH were analysed. Resistance trends were investigated using non\u2010linear analysis (generalized additive models) applied to time\u2010series stratified by livestock production and antibiotic. Irrespective of the species and the antibiotic considered, resistance signals over time showed no significant annual cycle. Resistance to third\u2010generation cephalosporins emerged during the period of the study, with a peak at 22% [20.5; 24.0] in poultry in 2010, decreasing afterwards, while it remained consistently below 10% for the other species. The proportion of resistance to fluoroquinolones was broadly similar between species and remained under 30%, with a slight decreasing trend after 2009. Resistances to tetracycline and amoxicillin remained high, between 90% and 40% over time in cattle and swine. After 2010, there was a decrease in resistance to these antibiotics for all species, especially to tetracycline for poultry with a drop from 84% in 2009 to 43% in 2015. These results contribute to risk assessment and constitute objective evidence on which to evaluate the efficacy of control measures implemented to limit AMR occurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/zph.12412","type":"journal-article","created":{"date-parts":[[2017,11,7]],"date-time":"2017-11-07T08:32:36Z","timestamp":1510043556000},"source":"Crossref","is-referenced-by-count":22,"title":["Antimicrobial resistance trends in <i>Escherichia coli<\/i> isolated from diseased food\u2010producing animals in France: A 14\u2010year period time\u2010series study"],"prefix":"10.1111","volume":"65","author":[{"given":"C.","family":"Boireau","sequence":"first","affiliation":[{"name":"\u00c9cole Nationale des Services V\u00e9t\u00e9rinaires, ENSV VetAgroSup  Lyon France"},{"name":"Laboratoire de Lyon Unit\u00e9 \u00c9pid\u00e9miologie Universit\u00e9 de Lyon ANSES  Lyon France"},{"name":"Epid\u00e9miologie des maladies Animales et zoonotiques, EPIA INRA VetAgroSup University of Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c9.","family":"Morignat","sequence":"additional","affiliation":[{"name":"Laboratoire de Lyon Unit\u00e9 \u00c9pid\u00e9miologie Universit\u00e9 de Lyon ANSES  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Cazeau","sequence":"additional","affiliation":[{"name":"Laboratoire de Lyon Unit\u00e9 \u00c9pid\u00e9miologie Universit\u00e9 de Lyon ANSES  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Jarrige","sequence":"additional","affiliation":[{"name":"Laboratoire de Lyon Unit\u00e9 \u00c9pid\u00e9miologie Universit\u00e9 de Lyon ANSES  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c9.","family":"Jouy","sequence":"additional","affiliation":[{"name":"Laboratoire de Ploufragan\u2010Plouzan\u00e9 Unit\u00e9 Mycoplasmologie\u2010Bact\u00e9riologie ANSES Universit\u00e9 Bretagne Loire Technop\u00f4le Saint\u2010Brieuc Armor  Ploufragan France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Haenni","sequence":"additional","affiliation":[{"name":"Laboratoire de Lyon Unit\u00e9 Antibior\u00e9sistance et Virulence Bact\u00e9riennes ANSES Universit\u00e9 de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.\u2010Y.","family":"Madec","sequence":"additional","affiliation":[{"name":"Laboratoire de Lyon Unit\u00e9 Antibior\u00e9sistance et Virulence Bact\u00e9riennes ANSES Universit\u00e9 de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Leblond","sequence":"additional","affiliation":[{"name":"Epid\u00e9miologie des maladies Animales et zoonotiques, EPIA INRA VetAgroSup University of Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5983-9263","authenticated-orcid":false,"given":"\u00c9.","family":"Gay","sequence":"additional","affiliation":[{"name":"Laboratoire de Lyon Unit\u00e9 \u00c9pid\u00e9miologie Universit\u00e9 de Lyon ANSES  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,7]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.6.5.733"},{"key":"e_1_2_11_3_1","unstructured":"Anses\u2010ANMV. 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