{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T19:19:56Z","timestamp":1792264796622,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T00:00:00Z","timestamp":1521936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["102507\/Z\/13\/Z"],"award-info":[{"award-number":["102507\/Z\/13\/Z"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Antibiotic resistance mediated by bacterial production of extended\u2010spectrum beta\u2010lactamase (ESBL) is a global threat to public health. ESBL resistance is most commonly hospital\u2010acquired; however, infections acquired outside of hospital settings have raised concerns over the role of livestock and wildlife in the zoonotic spread of ESBL\u2010producing bacteria. Only limited data are available on the circulation of ESBL\u2010producing bacteria in animals. Here, we report ESBL\u2010producing <jats:italic>Escherichia coli<\/jats:italic> in wild common vampire bats <jats:italic>Desmodus rotundus<\/jats:italic> and livestock near Lima, Peru. Molecular analyses revealed that most of this resistance resulted from the expression of <jats:italic>bla<\/jats:italic><jats:sub>CTX\u2010M\u201015<\/jats:sub> genes carried by plasmids, which are disseminating worldwide in hospital settings and have also been observed in healthy children of Peru. Multilocus sequence typing showed a diverse pool of <jats:italic>E.\u00a0coli<\/jats:italic> strains carrying this resistance that were not always host species\u2010specific, suggesting sharing of strains between species or infection from a common source. This study shows widespread ESBL resistance in wild and domestic animals, supporting animal communities as a potential source of resistance. Future work is needed to elucidate the role of bats in the dissemination of antibiotic\u2010resistant strains of public health importance and to understand the origin of the observed resistance.<\/jats:p>","DOI":"10.1111\/zph.12456","type":"journal-article","created":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T10:01:42Z","timestamp":1521972102000},"page":"454-458","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Extended\u2010spectrum beta\u2010lactamase\u2010producing <i>Escherichia coli<\/i> in common vampire bats <i>Desmodus rotundus<\/i> and livestock in Peru"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3920-9165","authenticated-orcid":false,"given":"J. A.","family":"Benavides","sequence":"first","affiliation":[{"name":"Institute of Biodiversity, Animal Health and Comparative Medicine University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Shiva","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine and Zootechnics University Cayetano Heredia of Peru  Lima Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Virhuez","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine and Zootechnics University Cayetano Heredia of Peru  Lima Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Tello","sequence":"additional","affiliation":[{"name":"Association for the Conservation and Development of Natural Resources  Lima Peru"},{"name":"Yunkawasi  Lima Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Appelgren","sequence":"additional","affiliation":[{"name":"Laboratoire de Bact\u00e9riologie Centre Hospitalier Universitaire (CHU) de Montpellier  Montpellier France"},{"name":"MIVEGEC (Laboratoire Maladies Infectieuses et Vecteurs, Ecologie, G\u00e9n\u00e9tique, Evolution et Contr\u00f4le) UMR CNRS 5290\/IRD 224 Universit\u00e9 Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Vendrell","sequence":"additional","affiliation":[{"name":"Department of Pathology Arnaud de Villeneuve Hospital CHU Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Solassol","sequence":"additional","affiliation":[{"name":"Department of Pathology Arnaud de Villeneuve Hospital CHU Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Godreuil","sequence":"additional","affiliation":[{"name":"Laboratoire de Bact\u00e9riologie Centre Hospitalier Universitaire (CHU) de Montpellier  Montpellier France"},{"name":"MIVEGEC (Laboratoire Maladies Infectieuses et Vecteurs, Ecologie, G\u00e9n\u00e9tique, Evolution et Contr\u00f4le) UMR CNRS 5290\/IRD 224 Universit\u00e9 Montpellier  Montpellier France"},{"name":"Department of Pathology Arnaud de Villeneuve Hospital CHU Montpellier  Montpellier France"},{"name":"INSERM U 1058  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. 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