{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T18:55:44Z","timestamp":1785869744721,"version":"3.56.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,6,6]],"date-time":"2018-06-06T00:00:00Z","timestamp":1528243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["Interamural grant"],"award-info":[{"award-number":["Interamural grant"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Seroprevalence of leptospirosis among a healthy population of the South Andaman Island was assessed through random sampling. Previous studies have high seroprevalences of up to 55% in general population and 65% in agricultural labourers. The study subjects (1,181 in total, 781 rural and 400 urban) were interviewed and tested for antibodies against <jats:italic>Leptospira<\/jats:italic>. Multivariate models were developed to determine the risk factors in the rural and the urban population. The overall seroprevalence was 10.9%, with rural (12.9%) being higher than the urban subjects (7.0%). The commonest infecting serogroup was Icterohaemorrhagiae (53.5%), followed by Grippotyphosa (13.2%). Compared to the earlier observation, seroprevalence was lower and an apparent shift in the infecting serogroup was found. This shift was in concordance with the changing trend in animal population. Significant difference in risk factors, both in rural and urban areas, was also observed. Similar trends in seroprevalence are being observed around the world. Therefore, time to time prevalence studies are needed for the development of effective control measure.<\/jats:p>","DOI":"10.1111\/zph.12478","type":"journal-article","created":{"date-parts":[[2018,6,6]],"date-time":"2018-06-06T07:51:23Z","timestamp":1528271483000},"page":"683-689","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Changing trend in the seroprevalence and risk factors of human leptospirosis in the South Andaman Island, India"],"prefix":"10.1111","volume":"65","author":[{"given":"Ratchagadasse","family":"Vimal Raj","sequence":"first","affiliation":[{"name":"Regional Medical Research Centre (ICMR) WHO Collaborating Centre for Diagnosis, Reference, Research and Training in Leptospirosis Port Blair Andaman and Nicobar Islands India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirubakaran","family":"Vinod Kumar","sequence":"additional","affiliation":[{"name":"Regional Medical Research Centre (ICMR) WHO Collaborating Centre for Diagnosis, Reference, Research and Training in Leptospirosis Port Blair Andaman and Nicobar Islands India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandan","family":"Lall","sequence":"additional","affiliation":[{"name":"Regional Medical Research Centre (ICMR) WHO Collaborating Centre for Diagnosis, Reference, Research and Training in Leptospirosis Port Blair Andaman and Nicobar Islands India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumaresan","family":"Vedhagiri","sequence":"additional","affiliation":[{"name":"Central Research Institute  Kasauli Himachal Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attayur Purushothaman","family":"Sugunan","sequence":"additional","affiliation":[{"name":"Regional Medical Research Centre (ICMR) WHO Collaborating Centre for Diagnosis, Reference, Research and Training in Leptospirosis Port Blair Andaman and Nicobar Islands India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ittoop Pulikkottil","family":"Sunish","sequence":"additional","affiliation":[{"name":"Regional Medical Research Centre (ICMR) WHO Collaborating Centre for Diagnosis, Reference, Research and Training in Leptospirosis Port Blair Andaman and Nicobar Islands India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameer","family":"Sharma","sequence":"additional","affiliation":[{"name":"Regional Medical Research Centre (ICMR) WHO Collaborating Centre for Diagnosis, Reference, Research and Training in Leptospirosis Port Blair Andaman and Nicobar Islands India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0116-486X","authenticated-orcid":false,"given":"Paluru","family":"Vijayachari","sequence":"additional","affiliation":[{"name":"Regional Medical Research Centre (ICMR) WHO Collaborating Centre for Diagnosis, Reference, Research and Training in Leptospirosis Port Blair Andaman and Nicobar Islands India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,6,6]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"251","article-title":"Vaccines against leptospirosis","volume":"387","author":"Adler B.","year":"2015","journal-title":"Current Topics in Microbiology and Immunology"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2000.63.249"},{"key":"e_1_2_8_4_1","first-page":"123","article-title":"Changes in the epidemiology of human leptospirosis in the Slovak Republic","volume":"97","author":"Bakoss P.","year":"1996","journal-title":"Bratislavske Lekarske Listy"},{"key":"e_1_2_8_5_1","volume-title":"District Census Handbook, Andaman & Nicobar Islands\u2010Village and Town Directory 36 Part 12A","author":"Census of India 2011","year":"2011"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003898"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0706.010611"},{"key":"e_1_2_8_8_1","doi-asserted-by":"crossref","first-page":"957","DOI":"10.4269\/ajtmh.2008.78.957","article-title":"Seroprevalence of leptospirosis and risk factor analysis in flood\u2010prone rural areas in Lao PDR","volume":"78","author":"Kawaguchi L.","year":"2008","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-7-125"},{"key":"e_1_2_8_10_1","first-page":"218","article-title":"Risk factors in the transmission of leptospiral infection","volume":"107","author":"Murhekar M. V.","year":"1998","journal-title":"Indian Journal of Medical Research"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10389-014-0611-1"},{"key":"e_1_2_8_12_1","first-page":"9","article-title":"Outbreak of leptospirosis with pulmonary involvement in north Andaman","volume":"102","author":"Sehgal S. C.","year":"1995","journal-title":"Indian Journal of Medical Research"},{"key":"e_1_2_8_13_1","first-page":"289","article-title":"A serosurvey for leptospirosis in North Andamans","volume":"12","author":"Sehgal S. C.","year":"1994","journal-title":"Indian Journal of Medical Microbiology"},{"issue":"2","key":"e_1_2_8_14_1","first-page":"170","article-title":"Leptospirosis disease burden estimation and surveillance networking in India","volume":"34","author":"Sehgal S. C.","year":"2003","journal-title":"Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268899002435"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2006.74.278"},{"key":"e_1_2_8_17_1","first-page":"94","article-title":"Clinico\u2010epidemiological study of hospitalized cases of severe leptospirosis","volume":"109","author":"Singh S. S.","year":"1999","journal-title":"Indian Journal of Medical Research"},{"key":"e_1_2_8_18_1","first-page":"67","article-title":"Risk factors associated with leptospirosis during an outbreak in Middle Andaman, India","volume":"130","author":"Sugunan A. P.","year":"2009","journal-title":"Indian Journal of Medical Research"},{"key":"e_1_2_8_19_1","doi-asserted-by":"crossref","unstructured":"Taylor R. J. &Goyle A. N.(1931).Leptospirosis in the Andamans. Supplement to Indian Journal of Medical Research Memoir no. 20. Indian Research Fund Association.Calcutta India:Thacker Spink & Co.","DOI":"10.2307\/3271745"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004122"},{"key":"e_1_2_8_21_1","first-page":"229","volume-title":"Contemporary topics in life sciences","author":"Vijayachari P.","year":"2014"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268804002948"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2007.08.012"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12038-008-0074-z"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-5916.162087"},{"key":"e_1_2_8_26_1","first-page":"91","volume-title":"The laboratory diagnosis of leptospirosis","author":"Wolff J. W.","year":"1954"}],"container-title":["Zoonoses and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fzph.12478","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/zph.12478","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T06:41:17Z","timestamp":1695019277000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/zph.12478"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,6]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.1111\/zph.12478"],"URL":"https:\/\/doi.org\/10.1111\/zph.12478","archive":["Portico"],"relation":{},"ISSN":["1863-1959","1863-2378"],"issn-type":[{"value":"1863-1959","type":"print"},{"value":"1863-2378","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,6]]},"assertion":[{"value":"2017-03-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}