{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T11:55:06Z","timestamp":1785498906309,"version":"3.56.0"},"reference-count":38,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,7,8]],"date-time":"2018-07-08T00:00:00Z","timestamp":1531008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["043TW008650"],"award-info":[{"award-number":["043TW008650"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["WHO\/AGISAR"],"award-info":[{"award-number":["WHO\/AGISAR"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Salmonella<\/jats:italic> is one of the common causes of food\u2010borne bacterial illnesses. The primary sources of human nontyphoidal <jats:italic>Salmonella<\/jats:italic> (NTS) infection are food animals. This study characterized temporally and spatially related <jats:italic>Salmonella<\/jats:italic> isolated during April 2013 to March 2014 from faeces of diarrhoeic human patients in Addis Ababa (<jats:italic>n<\/jats:italic>\u00a0=\u00a068) and food animals (<jats:italic>n<\/jats:italic>\u00a0=\u00a084) in Addis Ababa and surrounding districts (dairy cattle, <jats:italic>n<\/jats:italic>\u00a0=\u00a030; slaughtered cattle, <jats:italic>n<\/jats:italic>\u00a0=\u00a020; poultry, <jats:italic>n<\/jats:italic>\u00a0=\u00a026; swine <jats:italic>n<\/jats:italic>\u00a0=\u00a08). Isolates were serotyped, page typed and tested for antimicrobial susceptibility using Kirby\u2013Bauer disc diffusion method, and genotyped by pulsed\u2010field gel electrophoresis (PFGE). The dominant <jats:italic>Salmonella<\/jats:italic> serovars isolated from food animals were <jats:italic>S.<\/jats:italic> Saintpaul (38.1%), <jats:italic>S.<\/jats:italic> Typhimurium (17.9%) and <jats:italic>S<\/jats:italic>. Kentucky (9.5%), whereas in humans, <jats:italic>S.<\/jats:italic> Typhimurium (39.7%), <jats:italic>S.<\/jats:italic> Virchow (30.9%) and <jats:italic>S.<\/jats:italic> Kottbus (10.3%) were frequently isolated. Resistance to streptomycin, sulfisoxazole, tetracycline, ampicillin and cephalothin was higher in animal isolates than human isolates, and mean number of antimicrobials to which isolates were resistant was significantly higher in isolates from cattle and poultry compared to those from humans (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). All <jats:italic>S. <\/jats:italic>Kentucky isolated from animals and humans were multidrug resistant (MDR) with shared resistance phenotype (AmpCfCipTeSuSNa). Although this study involved small sample size and was not able to show clear epidemiological linkage among isolates from various sources, genotyping by PFGE analysis demonstrated circulation of closely related genotypes of <jats:italic>S.<\/jats:italic> Virchow, <jats:italic>S.<\/jats:italic> Typhimurium and <jats:italic>S.<\/jats:italic> Kentucky among humans and food animals. Detection of related <jats:italic>Salmonella <\/jats:italic>isolates from humans and animals, the high MDR status of isolates from animals and close proximity of farms and human residential areas in the absence of appropriate biosecurity present major public health problem. Integrated surveillance of <jats:italic>Salmonella <\/jats:italic>serovars in humans and animals and implementation of appropriate hazard analysis and pathogen control strategies along critical points of the food chain from farm to table is recommended.<\/jats:p>","DOI":"10.1111\/zph.12490","type":"journal-article","created":{"date-parts":[[2018,7,9]],"date-time":"2018-07-09T01:28:50Z","timestamp":1531099730000},"page":"766-776","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Phenotypic and genotypic characterization of temporally related nontyphoidal <i>Salmonella<\/i> strains isolated from humans and food animals in central Ethiopia"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6686-2370","authenticated-orcid":false,"given":"Tadesse","family":"Eguale","sequence":"first","affiliation":[{"name":"Aklilu Lemma Institute of Pathobiology Addis Ababa University Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Asrat","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology &amp; Parasitology, College of Health Sciences Addis Ababa University Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haile","family":"Alemayehu","sequence":"additional","affiliation":[{"name":"Aklilu Lemma Institute of Pathobiology Addis Ababa University Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismael","family":"Nana","sequence":"additional","affiliation":[{"name":"Department of Veterinary Preventive Medicine The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wondwossen A.","family":"Gebreyes","sequence":"additional","affiliation":[{"name":"Department of Veterinary Preventive Medicine The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John S.","family":"Gunn","sequence":"additional","affiliation":[{"name":"Department of Microbial Infection and Immunity, Infectious Diseases Institute The Ohio State University  Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ephrem","family":"Engidawork","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Clinical Pharmacy, College of Health Sciences Addis Ababa University Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,7,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-7843.2005.pto960401.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1025189204496"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11250-011-9941-y"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400056187"},{"issue":"01","key":"e_1_2_8_6_1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3855\/jidc.906","article-title":"Multidrug resistant Salmonella Concord is a major cause of salmonellosis in children in Ethiopia","volume":"5","author":"Beyene G.","year":"2011","journal-title":"J Infect Dev Ctries"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-11-49"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01885-10"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkt443"},{"key":"e_1_2_8_10_1","unstructured":"CLSI(2013).Performance Standards for Antimicrobial Susceptibility Testing; Twenty\u2010Third.Informational SupplementM100\u2010S23."},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063879300500311"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-017-0171-6"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-016-0638-2"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-015-1235-y"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jam.12579"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200004273421703"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01881"},{"key":"e_1_2_8_18_1","unstructured":"Grimont P. &Weill F.\u2010X.(2007).Antigenic formulas of Salmonella Serotypes WHO Collaborating Centre for Reference and Research on Salmonella.Paris Cedex France:Institut Pasteur."},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.6354"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1001.030171"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-13-253"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.46375-0"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir409"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1086\/650733"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2007.05.018"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11250-006-4325-4"},{"key":"e_1_2_8_27_1","first-page":"39","article-title":"Antimicrobial resistance pattern of Salmonella serotypes isolated from apparently healthy slaughtered camels (Camelus dromedarius) in eastern Ethiopia","volume":"117","author":"Molla B.","year":"2004","journal-title":"Berliner Und Munchener Tierarztliche Wochenschrift"},{"issue":"7","key":"e_1_2_8_28_1","first-page":"E070712.2","article-title":"Salmonella Kottbus outbreak in infants in Gran Canaria (Spain), caused by bottled water, August\u2010November 2006","volume":"12","author":"Palmera\u2010Su\u00e1rez R.","year":"2007","journal-title":"Eurosurveillance Weekly"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2006.3.59"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2014.10.014"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0144944"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-69.6.1452"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/2047-2994-1-12"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1503141112"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2011.0950"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2006.01466.x"},{"key":"e_1_2_8_37_1","volume-title":"Global foodborne infections network","author":"WHO","year":"2010"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-66.1.13"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11250-008-9181-y"}],"container-title":["Zoonoses and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fzph.12490","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/zph.12490","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T20:27:42Z","timestamp":1694896062000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/zph.12490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,8]]},"references-count":38,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1111\/zph.12490"],"URL":"https:\/\/doi.org\/10.1111\/zph.12490","archive":["Portico"],"relation":{},"ISSN":["1863-1959","1863-2378"],"issn-type":[{"value":"1863-1959","type":"print"},{"value":"1863-2378","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,8]]},"assertion":[{"value":"2017-10-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}