{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:21:12Z","timestamp":1762899672633,"version":"3.37.3"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,1,27]],"date-time":"2019-01-27T00:00:00Z","timestamp":1548547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Nasivvik Research Chair in Ecosystem Approaches to Northern Health","award":["\u00c9ric Dewailly scholarship"],"award-info":[{"award-number":["\u00c9ric Dewailly scholarship"]}]},{"DOI":"10.13039\/501100000156","name":"Fonds de Recherche du Qu\u00e9bec - Sant\u00e9","doi-asserted-by":"crossref","award":["PhD scholarship"],"award-info":[{"award-number":["PhD scholarship"]}],"id":[{"id":"10.13039\/501100000156","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Contact with infected saliva through the bite of a rabid animal is the main route of infection with the rabies <jats:italic>Lyssavirus<\/jats:italic> in humans. Although a few individuals have survived the infection, rabies remains the most lethal zoonotic infection worldwide. Over the last century, the dogma that rabies is invariably fatal has been challenged by the survival and recovery of infected animals. In humans, 11 studies have found rabies virus\u2010specific antibodies in unvaccinated individuals exposed to rabies virus reservoir species, suggesting the possibility of asymptomatic rabies virus infection, contact with non\u2010infectious virus or exposure to the virus without viral replication. Two of these studies were conducted in Arctic hunters. Considering the extensive exposure of Nunavik's Inuit to potentially infected animals through hunting, trapping, skinning and the preparation of Arctic carnivores, we analysed archived serum samples from the 2004 Nunavik Inuit Health Survey for the presence of rabies virus\u2010neutralizing antibodies (rVNA) in this sub\u2010population. A total of 196 participants who were considered at highest risk for exposure to rabies virus were targeted. Serum samples were tested for the presence of rVNA using a variation of the fluorescent antibody virus neutralization test, an assay recommended for the quantification of neutralizing antibody titres following vaccination. Our study identified two seropositive individuals among the 196 participants but a review of their medical record and a phone interview revealed previous vaccination. Our results do not provide evidence for naturally acquired rVNA in Nunavik's Inuit population.<\/jats:p>","DOI":"10.1111\/zph.12561","type":"journal-article","created":{"date-parts":[[2019,1,28]],"date-time":"2019-01-28T04:08:44Z","timestamp":1548648524000},"page":"533-539","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Assessment of naturally acquired neutralizing antibodies against rabies Lyssavirus in a subset of Nunavik\u2019s Inuit population considered most at risk of being exposed to rabid animals"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3497-3201","authenticated-orcid":false,"given":"Julie","family":"Ducrocq","sequence":"first","affiliation":[{"name":"D\u00e9partement de m\u00e9decine sociale et pr\u00e9ventive Universit\u00e9 Laval Qu\u00e9bec City Qu\u00e9bec Canada"},{"name":"Axe des populations et pratiques optimales en sant\u00e9 Centre de recherche du CHU de Qu\u00e9bec Qu\u00e9bec City Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Fran\u00e7ois","family":"Proulx","sequence":"additional","affiliation":[{"name":"Direction de sant\u00e9 publique R\u00e9gie r\u00e9gionale de la sant\u00e9 et des services sociaux du Nunavik Kuujjuaq Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beno\u00eet","family":"L\u00e9vesque","sequence":"additional","affiliation":[{"name":"D\u00e9partement de m\u00e9decine sociale et pr\u00e9ventive Universit\u00e9 Laval Qu\u00e9bec City Qu\u00e9bec Canada"},{"name":"Axe des populations et pratiques optimales en sant\u00e9 Centre de recherche du CHU de Qu\u00e9bec Qu\u00e9bec City Qu\u00e9bec Canada"},{"name":"Direction de la sant\u00e9 environnementale et de la toxicologie Institut national de sant\u00e9 publique du Qu\u00e9bec Qu\u00e9bec City Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1592-5167","authenticated-orcid":false,"given":"Gaston","family":"De Serres","sequence":"additional","affiliation":[{"name":"D\u00e9partement de m\u00e9decine sociale et pr\u00e9ventive Universit\u00e9 Laval Qu\u00e9bec City Qu\u00e9bec Canada"},{"name":"Direction des risques biologiques et sant\u00e9 au travail Institut national de sant\u00e9 publique du Qu\u00e9bec Qu\u00e9bec City Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heidi","family":"Wood","sequence":"additional","affiliation":[{"name":"Public Health Agency of Canada Winnipeg Manitoba Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3334-1349","authenticated-orcid":false,"given":"M\u00e9lanie","family":"Lemire","sequence":"additional","affiliation":[{"name":"D\u00e9partement de m\u00e9decine sociale et pr\u00e9ventive Universit\u00e9 Laval Qu\u00e9bec City Qu\u00e9bec Canada"},{"name":"Axe des populations et pratiques optimales en sant\u00e9 Centre de recherche du CHU de Qu\u00e9bec Qu\u00e9bec City Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10393-014-0923-1"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1135(90)90120-K"},{"volume-title":"The Natural history of rabies","year":"1991","author":"Baer G. M.","key":"e_1_2_8_4_1"},{"issue":"7","key":"e_1_2_8_5_1","first-page":"517","article-title":"Survey of raccoon hunters for rabies antibody titers: Pilot study","volume":"73","author":"Black D.","year":"1986","journal-title":"Journal of the Florida Medical Association"},{"key":"e_1_2_8_6_1","unstructured":"Canadian Food Inspection Agency (CFIA). (2018).Positive rabies in Canada. 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