{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:40:19Z","timestamp":1790340019870,"version":"4.1.0"},"reference-count":72,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,1,17]],"date-time":"2021-01-17T00:00:00Z","timestamp":1610841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2016H1D3A1909005"],"award-info":[{"award-number":["2016H1D3A1909005"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003627","name":"Rural Development Administration","doi-asserted-by":"publisher","award":["PJ013985032020"],"award-info":[{"award-number":["PJ013985032020"]}],"id":[{"id":"10.13039\/501100003627","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Salmonellosis is a major global public health issue; its most common infection, gastroenteritis, accounts for approximately 90 million illnesses and 150,000 mortalities per year. Eradicating salmonellosis requires surveillance, prevention and treatment, entailing large expenditures. However, it is difficult to control\n                    <jats:italic>Salmonella<\/jats:italic>\n                    transmission because it occurs via multiple routes; exotic reptiles are a reservoir of\n                    <jats:italic>Salmonella<\/jats:italic>\n                    and comprise one such route. As the popularity of exotic pets and animal exhibition has increased, human encounters with reptiles have also increased. As a result, reptile\u2010associated salmonellosis (RAS) has been recognized as an emerging disease. The development of antimicrobial resistance in RAS\u2010causing\n                    <jats:italic>Salmonella<\/jats:italic>\n                    sp. requires alternatives to antibiotics. In this study, bacteriophages have been established as an alternative to antibiotics because only target bacteria are lysed; thus, they are promising biocontrol agents. Here, bacteriophage pSal\u2010SNUABM\u201002, which infects and lyses reptile\n                    <jats:italic>Salmonella<\/jats:italic>\n                    isolates, was isolated and characterized. The morphology, host range, growth traits and stability of the phage were investigated. The phage was assigned to\n                    <jats:italic>Myoviridae<\/jats:italic>\n                    and was stable in the following conditions: pH 5\u20139, 4\u201337\u00b0C, and ultravioletA\/ultravioletB (UVA\/UVB) exposure.\n                    <jats:italic>Salmonella<\/jats:italic>\n                    clearance efficacy was tested using planktonic cell lysis activity and biofilm degradation on polystyrene 96\u2010well plates and reptile skin fragments. The phage exhibited vigorous lysis activity against planktonic cells. In in vitro biofilm degradation tests on reptile skin and polystyrene plates, both low\u2010 and high\u2010concentration phage treatments lowered bacterial cell viability by approximately 2.5\u20133 log colony\u2010forming units and also decreased biomass. Thus, bacteriophages are a promising alternative to antibiotics for the prevention and eradication of RAS.\n                  <\/jats:p>","DOI":"10.1111\/zph.12804","type":"journal-article","created":{"date-parts":[[2021,1,17]],"date-time":"2021-01-17T03:35:29Z","timestamp":1610854529000},"page":"131-143","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Bacteriophage as an alternative to prevent reptile\u2010associated\n                    <i>Salmonella<\/i>\n                    transmission"],"prefix":"10.1111","volume":"68","author":[{"given":"Jun","family":"Kwon","sequence":"first","affiliation":[{"name":"Laboratory of Aquatic Biomedicine College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Geun","family":"Kim","sequence":"additional","affiliation":[{"name":"Laboratory of Aquatic Biomedicine College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyoun Joong","family":"Kim","sequence":"additional","affiliation":[{"name":"Laboratory of Aquatic Biomedicine College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sib Sankar","family":"Giri","sequence":"additional","affiliation":[{"name":"Laboratory of Aquatic Biomedicine College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Wha","family":"Kim","sequence":"additional","affiliation":[{"name":"Laboratory of Aquatic Biomedicine College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Bin","family":"Lee","sequence":"additional","affiliation":[{"name":"Laboratory of Aquatic Biomedicine College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9821-387X","authenticated-orcid":false,"given":"Se Chang","family":"Park","sequence":"additional","affiliation":[{"name":"Laboratory of Aquatic Biomedicine College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002776"},{"issue":"22","key":"e_1_2_9_3_1","first-page":"19581","article-title":"Risk of Salmonella infection with exposure to reptiles in England, 2004\u20132007","volume":"15","author":"Aiken A. M.","year":"2010","journal-title":"Euro Surveillance"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-006-0849-1"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00049-07"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-9-75"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.5625\/lar.2016.32.3.166"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2011.04.052"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/29.12.2607"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13028-020-0502-0"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/4.6.1096"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1637\/8091-082007-Reg"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/08927014.2011.648927"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/10.1.111"},{"key":"e_1_2_9_15_1","first-page":"145","article-title":"Salmonella associated with captive and wild lizards in Malaysia","volume":"7","author":"Cheng B. Y.","year":"2014","journal-title":"Herpetology Notes"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113124"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1103.040694"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/21553769.2015.1051243"},{"key":"e_1_2_9_19_1","first-page":"235","volume-title":"Review of veterinary physiology","author":"Engelking L.","year":"2002"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-55.11.927"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1086\/500211"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-635X2005000400010"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.1997.tb00230.x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(98)70307-5"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2009.06.001"},{"key":"e_1_2_9_26_1","volume-title":"Medical Microbiology","author":"Giannella R. A.","year":"1996"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics3030270"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1562\/0031-8655(2002)0760561AHOUPF2.0.CO2"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2011.05.014"},{"issue":"4","key":"e_1_2_9_30_1","first-page":"237","article-title":"Phage therapy: A reappraisal of bacteriophages as antibiotics","volume":"51","author":"Inal J. M.","year":"2003","journal-title":"Archivum Immunologiae Et Therapiae Experimentalis"},{"key":"e_1_2_9_31_1","volume-title":"Serotypes and the Importance of Serotyping Salmonella","author":"Infectious Diseases (NCEZID)","year":"2020"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.4142\/jvs.2008.9.2.177"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-014-1655-7"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.3382\/japr.2010-00281"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1605(00)00466-9"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12701"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.2011.579246"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2020.105997"},{"issue":"1","key":"e_1_2_9_39_1","first-page":"1","article-title":"Isolation and characterisation of pVa\u201021, a giant bacteriophage with anti\u2010biofilm potential against Vibrio alginolyticus","volume":"9","author":"Kim S. G.","year":"2019","journal-title":"Scientific Reports"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2008.10.014"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-4565.2001.tb00307.x"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2010.08.001"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01114"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw413"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1638\/2014-0098R1.1"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1086\/650733"},{"issue":"3","key":"e_1_2_9_47_1","first-page":"S253","article-title":"Reptiles, amphibians, and human Salmonella infection: A population\u2010based, case\u2010control study","volume":"38","author":"Mermin J.","journal-title":"Clinical Infectious Diseases"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2016.07.033"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.67.97"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps.0681357"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2006.12.009"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1863-2378.2008.01196.x"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES2013.18.46.20634"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1078\/1438-4639-00184"},{"key":"e_1_2_9_55_1","first-page":"1","volume-title":"BSAVA manual of reptiles","author":"Rayment\u2010Dyble L. J.","year":"2004"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-0959-5528"},{"key":"e_1_2_9_57_1","first-page":"256","volume-title":"Molecular cloning: A laboratory manual","author":"Sambrook J.","year":"2001"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-2920.2005.00934.x"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0931-1793.2003.00710.x"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.3390\/vetsci7020056"},{"key":"e_1_2_9_61_1","volume-title":"Reptile\u2010associated Salmonellosis","author":"Spicker A. R.","year":"2013"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2011.01.038"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2009.0094"},{"issue":"3","key":"e_1_2_9_64_1","first-page":"210","article-title":"Salmonella: Clinical importance and evolution of nomenclature","volume":"30","author":"Su L.","year":"2007","journal-title":"Chang Gung Medical Journal"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-018-2685-4"},{"key":"e_1_2_9_66_1","first-page":"6","volume-title":"BSAVA manual of reptiles","author":"Varga M.","year":"2004"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens6030038"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12140"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1536(59)80069-3"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.35.11.2786-2790.1997"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines6030045"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10482-017-0844-4"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2017.12.007"}],"container-title":["Zoonoses and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/zph.12804","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/zph.12804","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/zph.12804","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T14:52:04Z","timestamp":1693579924000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/zph.12804"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,17]]},"references-count":72,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/zph.12804"],"URL":"https:\/\/doi.org\/10.1111\/zph.12804","archive":["Portico"],"relation":{},"ISSN":["1863-1959","1863-2378"],"issn-type":[{"value":"1863-1959","type":"print"},{"value":"1863-2378","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,17]]},"assertion":[{"value":"2020-06-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}