{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T14:16:57Z","timestamp":1782915417423,"version":"3.54.5"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,10,30]],"date-time":"2021-10-30T00:00:00Z","timestamp":1635552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Salmonella enterica<\/jats:italic> subsp. <jats:italic>enterica<\/jats:italic> serovar Kentucky is frequently isolated from poultry, dairy and beef cattle, the environment and people with clinical salmonellosis globally. However, the sources of this serovar and its diversity and antimicrobial resistance capacities remain poorly described in many regions. To further understand the genetic diversity and antimicrobial sensitivity patterns among <jats:italic>S<\/jats:italic>. Kentucky strains isolated from non\u2010human sources in Ireland, we sequenced and analysed the genomes of 61 isolates collected from avian, bovine, canine, ovine, piscine, porcine, environmental and vegetation sources between 2000 and 2016. The majority of isolates (<jats:italic>n<\/jats:italic>\u00a0=\u00a057, 93%) were sequence type (ST) 314, while only three isolates were ST198 and one was ST152. Several isolates were multidrug\u2010resistant (MDR) and 14 carried at least one acquired antimicrobial resistance gene. When compared to a database of publicly available ST314, four distinct clades were identified (clades I\u2013IV), with the majority of isolates from Ireland clustering together in Clade I. Two of the three ST198 isolates were characteristic of those originating outside of the Americas (Clade ST198.2), while one was distantly clustered with isolates from South and North America (Clade ST198.1). The genomes of the two clade ST198.2 isolates encoded <jats:italic>Salmonella<\/jats:italic> Genomic Island 1 (SGI1), were multidrug\u2010resistant and encoded polymorphisms in the DNA gyrase (<jats:italic>gyrA<\/jats:italic>) and DNA topoisomerase (<jats:italic>parC<\/jats:italic>) known to confer resistance to fluoroquinolones. The single ST152 isolate was from raw beef, clustered with isolates from food and bovine sources in North America and was pan\u2010susceptible. Results of this study indicate that most <jats:italic>S<\/jats:italic>. Kentucky isolates from non\u2010human sources in Ireland are closely related ST314 and only a few isolates are antimicrobial\u2010resistant. This study also demonstrates the presence of multidrug\u2010resistant ST198 in food sources in Ireland.<\/jats:p>","DOI":"10.1111\/zph.12884","type":"journal-article","created":{"date-parts":[[2021,10,30]],"date-time":"2021-10-30T12:11:55Z","timestamp":1635595915000},"page":"1-12","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Genomic diversity and resistome profiles of <i>Salmonella enterica<\/i> subsp. <i>enterica<\/i> serovar Kentucky isolated from food and animal sources in Ireland"],"prefix":"10.1111","volume":"69","author":[{"given":"Rosemarie","family":"Slowey","sequence":"first","affiliation":[{"name":"Department of Agriculture, Food and the Marine Laboratories Celbridge Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seon Woo","family":"Kim","sequence":"additional","affiliation":[{"name":"Environmental Microbial and Food Safety Laboratory Beltsville Agricultural Research Center Agricultural Research Service United States Department of Agriculture Beltsville MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deirdre","family":"Prendergast","sequence":"additional","affiliation":[{"name":"Department of Agriculture, Food and the Marine Laboratories Celbridge Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian","family":"Madigan","sequence":"additional","affiliation":[{"name":"Department of Agriculture, Food and the Marine Laboratories Celbridge Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo Ann S.","family":"Van Kessel","sequence":"additional","affiliation":[{"name":"Environmental Microbial and Food Safety Laboratory Beltsville Agricultural Research Center Agricultural Research Service United States Department of Agriculture Beltsville MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7996-1143","authenticated-orcid":false,"given":"Bradd J.","family":"Haley","sequence":"additional","affiliation":[{"name":"Environmental Microbial and Food Safety Laboratory Beltsville Agricultural Research Center Agricultural Research Service United States Department of Agriculture Beltsville MD 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