{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:47:05Z","timestamp":1790117225772,"version":"4.0.1"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T00:00:00Z","timestamp":1695945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003074","name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"publisher","award":["PICT 2019\u201001346"],"award-info":[{"award-number":["PICT 2019\u201001346"]}],"id":[{"id":"10.13039\/501100003074","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002923","name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005363","name":"Universidad de Buenos Aires","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005363","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hantavirus Pulmonary Syndrome (HPS) is an emerging infectious disease caused by orthohantaviruses in the Americas. In Argentina, since 1995, several reservoirs and virus variants have been described, but the northeastern and central endemic zones in the country include an area without human or rodent infections, despite sharing rodent species with areas with that disease. The aim of this study was to search for orthohantavirus in rodent communities that inhabit this area, which borders two endemic areas of HPS. Small rodents were captured in June of 2022 through a total effort of 644 trap nights distributed in five grids located in the Iber\u00e1 National Park, Corrientes, Northeastern Argentina. All rodents were sexed, weighed, and the species was recorded. Blood samples were extracted to detect ANDV\u2010specific immunoglobulin G (IgG), and to extract the RNA virus. Trimmed sequences were mapped against reference sequences from GenBank. We captured a total of 36 <jats:italic>Oligoryzomys flavescens<\/jats:italic> and 15 <jats:italic>Oxymycterus rufus<\/jats:italic>. We detected the <jats:italic>O.\u2009flavescens<\/jats:italic> species infected with Lechiguanas orthohantavirus in the camping area of the National Park. A nucleotide comparison with previously published sequences shows a 98.34% similarity to the virus obtained from a human case of HPS reported in the adjacent Misiones province. This study demonstrated, for the first time, that <jats:italic>O.\u2009flavescens<\/jats:italic> is a host of the Lechiguanas orthohantavirus in this zone and contributes to closing information gaps on the distribution of orthohantavirus in Argentina. Additionally, the high similarity with the hantavirus found in the human case of Misiones suggests that the reservoir in that province would also be <jats:italic>O.\u2009flavescens<\/jats:italic> (not previously confirmed). This information permits us to focus on the preventive measurements to protect the human population.<\/jats:p>","DOI":"10.1111\/zph.13079","type":"journal-article","created":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T08:45:35Z","timestamp":1695977135000},"page":"210-216","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Filling the gaps in the Argentinian distribution of orthohantavirus: First finding of Lechiguanas virus in rodents from Corrientes, Argentina"],"prefix":"10.1111","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7466-6305","authenticated-orcid":false,"given":"Isabel E.","family":"G\u00f3mez\u00a0Villafa\u00f1e","sequence":"first","affiliation":[{"name":"Facultad de Ciencias Exactas y Naturales, Instituto de Ecolog\u00eda, Gen\u00e9tica y Evoluci\u00f3n (Conicet\u2010UBA) Universidad de Buenos Aires  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6869-1707","authenticated-orcid":false,"given":"Carla M.","family":"Bellomo","sequence":"additional","affiliation":[{"name":"Laboratorio de Hantavirus, Servicio de Biolog\u00eda Molecular, Departamento de Virolog\u00eda Instituto Nacional de Enfermedades Infecciosas, ANLIS Dr. Carlos G. Malbr\u00e1n  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8899-468X","authenticated-orcid":false,"given":"Malena","family":"Rospide","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Exactas y Naturales, Instituto de Ecolog\u00eda, Gen\u00e9tica y Evoluci\u00f3n (Conicet\u2010UBA) Universidad de Buenos Aires  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6784-5046","authenticated-orcid":false,"given":"Paula","family":"Blanco","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Exactas y Naturales, Instituto de Ecolog\u00eda, Gen\u00e9tica y Evoluci\u00f3n (Conicet\u2010UBA) Universidad de Buenos Aires  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7274-9315","authenticated-orcid":false,"given":"Roc\u00edo","family":"Coelho","sequence":"additional","affiliation":[{"name":"Laboratorio de Hantavirus, Servicio de Biolog\u00eda Molecular, Departamento de Virolog\u00eda Instituto Nacional de Enfermedades Infecciosas, ANLIS Dr. Carlos G. Malbr\u00e1n  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel O.","family":"Alonso","sequence":"additional","affiliation":[{"name":"Laboratorio de Hantavirus, Servicio de Biolog\u00eda Molecular, Departamento de Virolog\u00eda Instituto Nacional de Enfermedades Infecciosas, ANLIS Dr. Carlos G. Malbr\u00e1n  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0566-2048","authenticated-orcid":false,"given":"Diana","family":"Arnica","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Exactas y Naturales, Instituto de Ecolog\u00eda, Gen\u00e9tica y Evoluci\u00f3n (Conicet\u2010UBA) Universidad de Buenos Aires  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juli\u00e1n","family":"Sanchez\u00a0Loria","sequence":"additional","affiliation":[{"name":"Unidad Centro de Gen\u00f3mica y Bioinform\u00e1tica ANLIS Dr. Carlos G. Malbr\u00e1n  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2810-6849","authenticated-orcid":false,"given":"Iara","family":"Figini","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Exactas y Naturales, Instituto de Ecolog\u00eda, Gen\u00e9tica y Evoluci\u00f3n (Conicet\u2010UBA) Universidad de Buenos Aires  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josefina","family":"Campos","sequence":"additional","affiliation":[{"name":"Unidad Centro de Gen\u00f3mica y Bioinform\u00e1tica ANLIS Dr. Carlos G. 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