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This study addresses the proximity of these captive animals to urban areas, necessitating focused monitoring for potential zoonotic enteropathogens. The present work aimed to investigate the presence of such zoonotic enteropathogens in faecal samples from captive large felid populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>A total of 108 faecal samples were collected in three circuses, five zoos and one rescue centre across Italy. <jats:italic>Salmonella<\/jats:italic> spp. isolation, serotyping and antimicrobial susceptibility testing were conducted on all samples. Additionally, 60 samples were also examined for gastrointestinal parasites using standard coprological techniques. <jats:italic>Giardia<\/jats:italic> spp. detection employed direct immunofluorescent staining and specific PCR, while <jats:italic>Toxoplasma gondii<\/jats:italic> was detected using PCR targeting B1 gene. A total of 51 <jats:italic>Salmonella enterica<\/jats:italic> subsp. <jats:italic>enterica<\/jats:italic> were isolated, with predominant serovariants including Infantis (43.1%), Coeln (11.8%) and Newport (11.8%). The captive felids likely act as asymptomatic carriers of foodborne <jats:italic>Salmonella<\/jats:italic>, with notable resistance ampicillin and trimethoprim\u2010sulfamethoxazole, no resistance to enrofloxacin was noted. Microscopic analysis revealed <jats:italic>Toxascaris leonina<\/jats:italic> eggs in 11 faecal samples (18.3%) and <jats:italic>Giardia duodenalis<\/jats:italic> cysts in one animal (1.7%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Captive animals in public settings may act as sources of <jats:italic>Salmonella<\/jats:italic> infection and enteroparasitosis for both occupational and general exposure. 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