{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T05:20:09Z","timestamp":1780636809040,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T00:00:00Z","timestamp":1703808000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p><jats:italic>Salmonella enterica<\/jats:italic> is a leading cause of acute enteritis in people, and dairy cattle are an important reservoir of this pathogen. The objective of this study was to analyse serotype and anti\u2010microbial resistance trends of <jats:italic>Salmonella<\/jats:italic> isolated from dairy cattle in the United States between 2007 and 2021.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>We collected data for bovine <jats:italic>Salmonella<\/jats:italic> isolates obtained from samples submitted to Cornell University's Animal Health Diagnostic Center (AHDC). We analysed 5114 isolates for serotype trends, and a subset of 2521 isolates tested for anti\u2010microbial susceptibility were analysed for resistance trends. The most frequently identified serotypes were <jats:italic>Salmonella<\/jats:italic> Cerro, Dublin, Typhimurium, Montevideo, 4,[5],12:i:\u2010, and Newport. Among these serotypes, a Cochran\u2013Armitage trend test determined there was a significant increase in the proportion of isolates serotyped as <jats:italic>Salmonella<\/jats:italic> Dublin (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001) and Montevideo (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001) over time. There was a significant decrease in the proportion of isolates serotyped as <jats:italic>Salmonella<\/jats:italic> Cerro (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), Typhimurium (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), and Newport (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). For the anti\u2010microbial resistance (AMR) analysis, we found an overall increase in the proportion of multi\u2010drug\u2010resistant isolates over time (<jats:italic>p<\/jats:italic>\u2009=\u20090.009). There was a significant increase in the proportion of isolates resistant to ampicillin (<jats:italic>p<\/jats:italic>\u2009=\u20090.007), florfenicol (<jats:italic>p<\/jats:italic>\u2009=\u20090.0002), and ceftiofur (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001) and a marginal increase in resistance to enrofloxacin (<jats:italic>p<\/jats:italic>\u2009=\u20090.05). There was a significant decrease in the proportion of isolates resistant to spectinomycin (<jats:italic>p<\/jats:italic>\u2009=\u20090.0002), trimethoprim\/sulphamethoxazole (<jats:italic>p<\/jats:italic>\u2009=\u20090.01), sulphadimethoxine (<jats:italic>p<\/jats:italic>\u2009=\u20090.003), neomycin (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), and gentamicin (<jats:italic>p<\/jats:italic>\u2009=\u20090.0002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our results provide evidence of an increase in resistance to key anti\u2010microbial agents, although the observed trends were driven by the sharp increase in the proportion of <jats:italic>Salmonella<\/jats:italic> Dublin isolates over time.<\/jats:p><\/jats:sec>","DOI":"10.1111\/zph.13108","type":"journal-article","created":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T05:30:20Z","timestamp":1703914220000},"page":"359-368","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Serotype and anti\u2010microbial resistance trends among bovine <i>Salmonella<\/i> isolates from samples submitted to a veterinary diagnostic laboratory in central New York, 2007\u20132021"],"prefix":"10.1111","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2899-0283","authenticated-orcid":false,"given":"Maya J.","family":"Craig","sequence":"first","affiliation":[{"name":"Department of Public and Ecosystem Health, College of Veterinary Medicine Cornell University  Ithaca New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3327-596X","authenticated-orcid":false,"given":"Kevin J.","family":"Cummings","sequence":"additional","affiliation":[{"name":"Department of Public and Ecosystem Health, College of Veterinary Medicine Cornell University  Ithaca New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa S.","family":"Aprea","sequence":"additional","affiliation":[{"name":"Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine Cornell University  Ithaca New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca J.","family":"Franklin\u2010Guild","sequence":"additional","affiliation":[{"name":"Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine Cornell University  Ithaca New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Altier","sequence":"additional","affiliation":[{"name":"Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine Cornell University  Ithaca New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876\u2010021\u201001719\u20103"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5450.50"},{"key":"e_1_2_8_4_1","unstructured":"Center for Disease Control and Prevention (CDC). (2019).Questions and Answers|Salmonella|CDC.https:\/\/www.cdc.gov\/salmonella\/general\/index.html"},{"key":"e_1_2_8_5_1","unstructured":"Center for Disease Control and Prevention (CDC). 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