{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T11:38:15Z","timestamp":1789040295327,"version":"build-2803163510"},"reference-count":66,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T00:00:00Z","timestamp":1708646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007251","name":"National Research University Higher School of Economics","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007251","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<jats:bold>s<\/jats:bold><\/jats:title><jats:p>Haemorrhagic fever with renal syndrome (HFRS) is a significant zoonotic disease transmitted by rodents. The distribution of HFRS in the European part of Russia has been studied quite well; however, much less is known about the endemic area in the Russian Far East. The mutual influence of the epidemic situation in the border regions and the possibility of cross\u2010border transmission of infection remain poorly understood. This study aims to identify the spatiotemporal hot spots of the incidence and the impact of environmental drivers on the HFRS distribution in the Russian Far East.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>A two\u2010scale study design was performed. Kulldorf's spatial scan statistic was used to conduct spatiotemporal analysis at a regional scale from 2000 to 2020. In addition, an ecological niche model based on maximum entropy was applied to analyse the contribution of various factors and identify spatial favourability at the local scale. One spatiotemporal cluster that existed from 2002 to 2011 and located in the border area and one pure temporal cluster from 2004 to 2007 were revealed. The best suitability for orthohantavirus persistence was found along rivers, including those at the Chinese\u2013Russian border, and was mainly explained by land cover, NDVI (as an indicator of vegetation density and greenness) and elevation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Despite the stable incidence in recent years in, targeted prevention strategies are still needed due to the high potential for HRFS distribution in the southeast of the Russian Far East.<\/jats:p><\/jats:sec>","DOI":"10.1111\/zph.13118","type":"journal-article","created":{"date-parts":[[2024,2,24]],"date-time":"2024-02-24T04:29:25Z","timestamp":1708748965000},"page":"489-502","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Spatial and temporal patterns of haemorrhagic fever with renal syndrome (<scp>HFRS<\/scp>) and the impact of environmental drivers in a border area of the Russian Far East"],"prefix":"10.1111","volume":"71","author":[{"given":"Natalia","family":"Shartova","sequence":"first","affiliation":[{"name":"International Laboratory of Landscape Ecology Higher School of Economics  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7378-3531","authenticated-orcid":false,"given":"Fedor","family":"Korennoy","sequence":"additional","affiliation":[{"name":"FGBI Federal Center for Animal Health (FGBI ARRIAH), mkr. Yurevets  Vladimir Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana","family":"Zelikhina","sequence":"additional","affiliation":[{"name":"Faculty of Geography Lomonosov Moscow State University  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varvara","family":"Mironova","sequence":"additional","affiliation":[{"name":"Faculty of Geography Lomonosov Moscow State University  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Land Surface Pattern and Simulation, Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana","family":"Malkhazova","sequence":"additional","affiliation":[{"name":"Faculty of Geography Lomonosov Moscow State University  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,23]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705\u2010017\u20103358\u20105"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ecog.01132"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s42452\u2010021\u201004679\u20101"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.31631\/2073-3046-2017-16-3-90-95"},{"issue":"51","key":"e_1_2_11_6_1","first-page":"5","article-title":"Peculiarities of natural focality of hantavirus zoonoses","volume":"2","author":"Bernstein A. 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