{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:53:02Z","timestamp":1788691982292,"version":"build-2803163510"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,5,5]],"date-time":"2024-05-05T00:00:00Z","timestamp":1714867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Rabies virus (RABV) is the etiologic agent of rabies, a fatal brain disease in mammals. Rabies circulation has historically involved the dog has the main source of human rabies worldwide. Nevertheless, in Colombia, cats (<jats:italic>Felis catus<\/jats:italic>) have become a relevant species in the epidemiology of rabies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To characterize rabies cases in humans in Colombia in the last three decades in the context of the epidemiology of the aggressor animal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We conducted a retrospective longitudinal epidemiological study of human rabies caused by cats\u2019 aggression, collecting primary and secondary information. Variables considered included the demography of the patient, symptoms, information about the aggressor animal as the source of infection and the viral variant identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found that the distribution of rabies incidence over the years has been constant in Colombia. Nevertheless, between 2003 and 2012 a peak of cases occurred in rural Colombia where cats were the most frequent aggressor animal reported. Most cats involved in aggression were unvaccinated against rabies. Cat's clinical signs at the time of the report of the human cases included hypersalivation and changes in behaviour. Human patients were mostly children and female and the exposure primarily corresponded to bite and puncture lacerations in hands. The RABV lineage detected in most cases corresponded to variant 3, linked to the common vampire bat (<jats:italic>Desmodus rotundus<\/jats:italic>). The geographical presentation of cat borne RABV in humans occurred along the Andes mountains, epidemiologically known as the rabies red Andean corridor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>By finding cats as the primary source of rabies spillover transmission in Colombia, this report highlights the importance of revising national rabies control and prevention protocol in countries in the Andes region.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results demonstrate that rabies vaccination for outdoor cats needs to prioritize to reduce the number of rabies\u2010related human deaths.<\/jats:p><\/jats:sec>","DOI":"10.1111\/zph.13141","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T04:14:12Z","timestamp":1714968852000},"page":"600-608","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Human cat borne rabies as the new epidemiology of the disease in the Andes mountains"],"prefix":"10.1111","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3337-8686","authenticated-orcid":false,"given":"Samir","family":"Meri\u00f1o\u2010Olivella","sequence":"first","affiliation":[{"name":"Centauro Research Group, Facultad de Ciencias Agrarias Universidad de Antioquia  Medellin Colombia"},{"name":"Impronta, Facultad de Medicina Veterinaria y Zootecnia Universidad Cooperativa de Colombia  Ibagu\u00e9 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5297-1605","authenticated-orcid":false,"given":"Mar\u00eda","family":"del Pilar\u00a0S\u00e1nchez\u2010Bonilla","sequence":"additional","affiliation":[{"name":"Impronta, Facultad de Medicina Veterinaria y Zootecnia Universidad Cooperativa de Colombia  Ibagu\u00e9 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5735-2750","authenticated-orcid":false,"given":"Luis E.","family":"Escobar","sequence":"additional","affiliation":[{"name":"Department of Fish and Wildlife Conservation Virginia Tech  Blacksburg Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8836-8827","authenticated-orcid":false,"given":"Nathalia M.","family":"Correa\u2010Valencia","sequence":"additional","affiliation":[{"name":"Centauro Research Group, Facultad de Ciencias Agrarias Universidad de Antioquia  Medellin Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/v6082974"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2023.106032"},{"key":"e_1_2_9_4_1","unstructured":"Cediel N.(2020).El abordaje una salud para la comprensi\u00f3n de la rabia en Colombia. Conference: Luchando juntos contra la rabia de origen silvestre.Instituto Colombiano Agropecuario.https:\/\/doi.org\/10.13140\/RG.2.2.15554.40642"},{"key":"e_1_2_9_5_1","unstructured":"Centers for Disease Control and Prevention (CDC). (2019).Rabies.https:\/\/www.cdc.gov\/rabies\/es\/index.html"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2004.10.013"},{"key":"e_1_2_9_7_1","unstructured":"El Paciente Colombiano. (2019).Rabia silvestre: un caso en Mesitas del Colegio Cundinamarca.https:\/\/elpacientecolombiano.com\/datos\u2010y\u2010noticias\/rabia\u2010silvestre\u2010un\u2010caso\u2010en\u2010mesitas\u2010del\u2010colegio\u2010cundinamarca\/"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0034\u201089102008000600005"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1474\u20104422(02)00041\u20108"},{"key":"e_1_2_9_10_1","unstructured":"Instituto Colombiano Agropecuario (ICA). (2021).El ICA implementa medidas para apoyar atenci\u00f3n de caso de rabia en humano detectado en Huila.https:\/\/www.ica.gov.co\/noticias\/ica\u2010implementa\u2010medidas\u2010atencion\u2010rabia"},{"key":"e_1_2_9_11_1","unstructured":"Instituto Nacional de Salud de Colombia (INS). (2008).Informe Quincenal Epidemiol\u00f3gico Nacional.https:\/\/www.ins.gov.co\/buscador\u2010eventos\/IQEN\/IQEN%20vol%2013%202008%20num%2019.pdf"},{"key":"e_1_2_9_12_1","unstructured":"Instituto Nacional de Salud de Colombia (INS). (2009).Informe Quincenal Epidemiol\u00f3gico Nacional.https:\/\/www.ins.gov.co\/buscador\/IQEN\/IQEN%20vol%2014%202009%20num%2014.pdf"},{"key":"e_1_2_9_13_1","unstructured":"Instituto Nacional de Salud de Colombia (INS). (2012).Instituto Nacional de Salud confirma caso de rabia humana en Roldanillo.https:\/\/www.ins.gov.co\/Noticias\/Paginas\/ins\u2010confirma\u2010caso\u2010de\u2010rabia\u2010humana\u2010en\u2010roldanillo.aspx"},{"key":"e_1_2_9_14_1","unstructured":"Instituto Nacional de Salud de Colombia (INS). (2018).Agresiones y contactos con animales potencialmente transmisores de la rabia \u2013 rabia humana Colombia 2018.https:\/\/www.ins.gov.co\/buscador\u2010eventos\/Informesdeevento\/AGRESIONES%20POR%20ANIMALES%20TRANSMISORES%20DE%20RABIA_2018_.pdf"},{"key":"e_1_2_9_15_1","doi-asserted-by":"crossref","unstructured":"Instituto Nacional de Salud de Colombia (INS). (2019a).Bolet\u00edn Epidemiol\u00f3gico semana 38 2019.https:\/\/www.ins.gov.co\/buscador\u2010eventos\/BoletinEpidemiologico\/2019_Boletin_epidemiologico_semana_38.pdf","DOI":"10.33610\/23576189.2019.38"},{"key":"e_1_2_9_16_1","unstructured":"Instituto Nacional de Salud de Colombia (INS). 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(2012).Modelo de estrategia de vigilancia prevenci\u00f3n y control de la Rabia silvestre en comunidades de alto riesgo.https:\/\/www.minsalud.gov.co\/sites\/rid\/Lists\/BibliotecaDigital\/RIDE\/VS\/PP\/SA\/Modelo\u2010estrategia\u2010prevencion\u2010vigilancia\u2010control\u2010rabia\u2010silvestre\u2010comunidades\u2010alto\u2010riesgo.pdf"},{"key":"e_1_2_9_21_1","unstructured":"Ministerio de Salud de Colombia (MinSalud). (2016).An\u00e1lisis de situaci\u00f3n de salud de la dimensi\u00f3n vida saludable y condiciones transmisibles Colombia.https:\/\/www.minsalud.gov.co\/sites\/rid\/Lists\/BibliotecaDigital\/RIDE\/VS\/PP\/ENT\/asis\u2010dimension\u2010vida\u2010saludable\u2010enfermedades\u2010transmisibles.pdf"},{"key":"e_1_2_9_22_1","unstructured":"Ministerio de Salud de Colombia (MinSalud). 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