{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:51:49Z","timestamp":1788691909568,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T00:00:00Z","timestamp":1718928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004351","name":"Sultan Qaboos University","doi-asserted-by":"publisher","award":["IG\/AGR\/ANVS\/19\/03"],"award-info":[{"award-number":["IG\/AGR\/ANVS\/19\/03"]}],"id":[{"id":"10.13039\/501100004351","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Rabies virus (RV) is endemic in some Arabian countries. However, it is difficult to control RV without understanding the epidemiological evolution of endemic RV isolates. The current study aimed to characterize RV from domestic and wild animal clinical cases in Oman.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Twelve brain samples from domestic (Five camels, three goats and one cattle) and wild animals (Two foxes and one honey badger) were investigated from different locations in Oman between 2017 and 2020. All samples were confirmed by RV nucleoprotein (N) gene\u2010specific primers. Seven out of the 12 amplified samples were successfully sequenced and subjected to sequence and phylogenetic analysis. The detected RVs shared an in\u2010between 96.8%\u201398.7% and 96.9%\u201399% nucleotide and amino acid identities, respectively. However, the wild animal RVs shared only 92.6%\u201393.9% and 95.9% nucleotide and amino acid identities with the domestic animal RVs, respectively. Negri bodies were detected histologically in six brain samples from camels (<jats:italic>n<\/jats:italic>\u2009=\u20093), goats (<jats:italic>n<\/jats:italic>\u2009=\u20091) and foxes (<jats:italic>n<\/jats:italic>\u2009=\u20092). The RVs from domestic animals shared 97%\u201398.7% and 98%\u2013100% nucleotide and amino acid identities with the previously published fox RVs from Oman and Gulf countries. Phylogenetic analysis suggested that all RV sequences belong to a distinct clade confined to the previously reported clade V within the Middle Eastern Cluster.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>As indicated by the analysis of RVs from different locations between 2017 and 2020, a genetic variant isolated to the Gulf region may exist within the Middle East clade. Moreover, it appears that new RV lineages are emerging rapidly within this region. Therefore, a comprehensive genomic and phylogenetic analysis of the circulating RV is important for the development of future prevention and control strategies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/zph.13164","type":"journal-article","created":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T04:09:53Z","timestamp":1719029393000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Molecular characterization of rabies virus from wild and domestic animals in the Sultanate of Oman"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3273-9593","authenticated-orcid":false,"given":"Haytham","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Animal and Veterinary Sciences, College of Agricultural and Marine Sciences Sultan Qaboos University  Muscat Sultanate of Oman"},{"name":"Department of Pathology, Faculty of Veterinary Medicine Zagazig University  Zagazig Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Ali","sequence":"additional","affiliation":[{"name":"Poultry Diseases Department, Faculty of Veterinary Medicine Beni\u2010Suef University  Beni\u2010Suef Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julanda","family":"Al\u00a0Mawly","sequence":"additional","affiliation":[{"name":"Central Laboratory for Animal Health Ministry of Agriculture and Fisheries  Muscat Sultanate of Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossam G.","family":"Tohamy","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Veterinary Medicine Alexandria University  Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud S.","family":"El\u2010Neweshy","sequence":"additional","affiliation":[{"name":"Central Laboratory for Animal Health Ministry of Agriculture and Fisheries  Muscat Sultanate of Oman"},{"name":"Department of Pathology, Faculty of Veterinary Medicine Kafrelsheikh University  Kafrelsheikh Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"591","DOI":"10.26719\/2015.21.8.591","article-title":"Epidemiology of rabies in Oman: A retrospective study (1991\u20102013)","volume":"21","author":"Abaidani I. 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