{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:23:00Z","timestamp":1790821380223,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000974","name":"Australian Centre for International Agricultural Research","doi-asserted-by":"publisher","award":["LS\/2014\/055"],"award-info":[{"award-number":["LS\/2014\/055"]}],"id":[{"id":"10.13039\/501100000974","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Taenia solium<\/jats:italic>\n                      places substantial burden on communities in low and middle\u2010income countries, where neurocysticercosis is a leading cause of preventable epilepsy. Current diagnostic tests for\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>T. solium<\/jats:italic>\n                      <\/jats:styled-content>\n                      are not suited for low resource settings or perform poorly. Several risk\u2010assessment tools have been developed to support countries in identifying areas for further\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>T. solium<\/jats:italic>\n                      <\/jats:styled-content>\n                      investigation and intervention. These tools are based on risk, rather than disease data, and have yet to be validated against biological results.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Two national quantitative risk\u2010assessment tools (\n                      <jats:styled-content style=\"fixed-case\">LISA<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">MCDA<\/jats:styled-content>\n                      ), two local semi\u2010quantitative tools (rapid and in\u2010depth), and a local qualitative tool (workshop) had their performance assessed against biological\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>T. solium<\/jats:italic>\n                      <\/jats:styled-content>\n                      taeniasis data from 28 villages. The final risk category, risk score and individual components of each tool were assessed independently against village\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>T. solium<\/jats:italic>\n                      <\/jats:styled-content>\n                      status by logistic regression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>T. solium<\/jats:italic>\n                      <\/jats:styled-content>\n                      positive villages had higher odds of being high\u2010risk villages for all tools, however, this was only significant for the\n                      <jats:styled-content style=\"fixed-case\">LISA<\/jats:styled-content>\n                      and workshop tools. For the\n                      <jats:styled-content style=\"fixed-case\">LISA<\/jats:styled-content>\n                      tool, the median risk score was also significantly greater in positive villages. A unit increase in\n                      <jats:styled-content style=\"fixed-case\">LISA<\/jats:styled-content>\n                      risk score led to a significant increase in the odds of a village being positive for\n                      <jats:italic>T. solium<\/jats:italic>\n                      . Other tools that calculated risk scores also showed similar results, however, were not statistically significant. All positive villages were hotspots for unimproved toilets by the\n                      <jats:styled-content style=\"fixed-case\">LISA<\/jats:styled-content>\n                      tool. The open defaecation component of the local rapid tool was the only component of any tool to demonstrate a significant relationship with positive\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>T. solium<\/jats:italic>\n                      <\/jats:styled-content>\n                      villages.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      This first biological validation of\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>T. solium<\/jats:italic>\n                      <\/jats:styled-content>\n                      risk\u2010assessment tools demonstrates that there are multiple tools that should be considered for further development. Supporting endemic countries to implement recently developed risk\u2010assessment tools is consistent with the World Health Organization's goal of intensified control of\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>T. solium<\/jats:italic>\n                      <\/jats:styled-content>\n                      in hyperendemic areas.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/zph.70023","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T06:44:45Z","timestamp":1768545885000},"page":"115-127","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The First Biological Validation of\n                    <scp>\n                      <i>Taenia solium<\/i>\n                    <\/scp>\n                    Risk Assessment Tools"],"prefix":"10.1111","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2741-1059","authenticated-orcid":false,"given":"Andrew","family":"Larkins","sequence":"first","affiliation":[{"name":"School of Medical, Molecular and Forensic Sciences Murdoch University  Perth Australia"},{"name":"Centre for Biosecurity and one Health, Harry Butler Institute Murdoch University  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2094-6728","authenticated-orcid":false,"given":"Davina","family":"Boyd","sequence":"additional","affiliation":[{"name":"Centre for Sustainable Farming Systems, Food Futures Institute Murdoch University  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oula","family":"Bouphakaly","sequence":"additional","affiliation":[{"name":"Faculty of Agriculture National University of Laos  Vientiane Lao PDR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bounnaloth","family":"Insisiengmay","sequence":"additional","affiliation":[{"name":"Department of Communicable Disease Control Ministry of Health  Vientiane Lao PDR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5890-7954","authenticated-orcid":false,"given":"Malavanh","family":"Chittavong","sequence":"additional","affiliation":[{"name":"Faculty of Agriculture National University of Laos  Vientiane Lao PDR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8218-7048","authenticated-orcid":false,"given":"Amanda","family":"Ash","sequence":"additional","affiliation":[{"name":"School of Medical, Molecular and Forensic Sciences Murdoch University  Perth Australia"},{"name":"Centre for Biosecurity and one Health, Harry Butler Institute Murdoch University  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,15]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"Information and Likelihood Theory: A Basis for Model Selection and Inference","author":"Anderson D. 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