{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T09:16:20Z","timestamp":1788340580945,"version":"build-2803163510"},"reference-count":68,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100025246","name":"Departament de Recerca i Universitats, Generalitat de Catalunya","doi-asserted-by":"publisher","award":["FI\u2010SDUR 2020\u201000376"],"award-info":[{"award-number":["FI\u2010SDUR 2020\u201000376"]}],"id":[{"id":"10.13039\/501100025246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                      <\/jats:styled-content>\n                      is a pathogen associated with healthcare\u2010acquired infections and antimicrobial resistance (AMR) to beta\u2010lactams and carbapenems. Although wild animals are not typically exposed to antibiotics, they can harbour resistant strains. The European hedgehog (\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Erinaceus europaeus<\/jats:italic>\n                      <\/jats:styled-content>\n                      ) is increasingly found in urban areas, where it interacts with humans and livestock. Studies have identified concerning levels of AMR in hedgehogs, including Extended\u2010Spectrum \u03b2\u2010Lactam (ESBL) and carbapenems\u2010resistant\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                      <\/jats:styled-content>\n                      strains.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This study focuses on\n                      <jats:italic>Klebsiella<\/jats:italic>\n                      spp. isolated in hedgehogs from urban areas, using whole\u2010genome sequencing (WGS). We compared these isolates with openly available strains isolated from humans in the same region with the objective to have a thorough understanding of ST, AMR gene, and plasmid overlap between human and environmental compartments.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      High AMR gene levels, including the carbapenemase\n                      <jats:italic>bla<\/jats:italic>\n                      <jats:sub>OXA\u201048<\/jats:sub>\n                      , were found in the hedgehog population. Notably, human nosocomial clones, including ST307 and ST392, globally distributed sequence types also found in wildlife, were identified in both hedgehogs and humans. The presence of conjugative plasmids, including IncFIB(K) and IncL1 types, was identified in both hedgehogs and humans, highlighting plasmid dissemination as a significant factor in AMR spread.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Although no direct transmission from wildlife to hospital settings has been conclusively demonstrated, our findings suggest that hedgehogs may play a role in bridging environmental and healthcare environments. The study underscores the need for further investigation into multidrug\u2010resistant\n                      <jats:italic>Klebsiella<\/jats:italic>\n                      spp. and other resistant bacteria in wildlife to better understand their potential role in the dissemination of resistance genes across ecosystems.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/zph.70072","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T06:12:59Z","timestamp":1781590379000},"page":"516-527","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Whole Genome Characterization of\n                    <i>Klebsiella<\/i>\n                    Strains in European Hedgehogs and Human Nosocomial Settings Identified Shared Sequence Types, Antimicrobial Resistance Genes and Plasmids"],"prefix":"10.1111","volume":"73","author":[{"given":"Biel","family":"Garcias","sequence":"first","affiliation":[{"name":"Department Sanitat i Anatomia Animals, Veterinary Faculty Universitat Aut\u00f2noma de Barcelona (UAB)  Cerdanyola del Vall\u00e8s Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Seminati","sequence":"additional","affiliation":[{"name":"Department Sanitat i Anatomia Animals, Veterinary Faculty Universitat Aut\u00f2noma de Barcelona (UAB)  Cerdanyola del Vall\u00e8s Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4393-5829","authenticated-orcid":false,"given":"Carolin M.","family":"Kobras","sequence":"additional","affiliation":[{"name":"Sir William Dunn School of Pathology University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel K.","family":"Sheppard","sequence":"additional","affiliation":[{"name":"Ineos Oxford Institute for Antimicrobial Research, Department of Biology University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael A.","family":"Molina\u2010L\u00f3pez","sequence":"additional","affiliation":[{"name":"Centre de Fauna Salvatge de Torreferrussa, Forestal Catalana, S.A., Generalitat de Catalunya  Santa Perpetua de la Mogoda Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9027-9452","authenticated-orcid":false,"given":"Laila","family":"Darwich","sequence":"additional","affiliation":[{"name":"Department Sanitat i Anatomia Animals, Veterinary Faculty Universitat Aut\u00f2noma de Barcelona (UAB)  Cerdanyola del Vall\u00e8s Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.153632"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.001132"},{"key":"e_1_2_11_4_1","volume-title":"FastQC","author":"Andrews S.","year":"2010"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000093"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsbl.2016.0137"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.8.2230\u20102230.2000"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2016.0323"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/aem.00465\u201022"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02557\u201020"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2017.06.004"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dku340"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu170"},{"key":"e_1_2_11_14_1","doi-asserted-by":"crossref","unstructured":"Bouras G. G.Houtak R. R.Wick et\u00a0al.2024. \u201cHybracter: Enabling Scalable Automated Complete and Accurate Bacterial Genome Assemblies.\u201dBioRxiv.https:\/\/doi.org\/10.1101\/2023.12.12.571215.","DOI":"10.1101\/2023.12.12.571215"},{"key":"e_1_2_11_15_1","volume-title":"Methods in Molecular Biology","author":"Carattoli A.","year":"2020"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12182"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.7203\/metode.13.23653"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0210686"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.01242\u201022"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.7589\/2019\u201003\u2010068"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkad047"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12941\u2010019\u20100343\u20108"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000748"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkac041"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani11102837"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(17)30489\u20109"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0160754"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12915\u2010021\u201001094\u20101"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0195\u20105616(94)50006\u20108"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.landurbplan.2011.05.010"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s44197\u2010024\u201000323\u20104"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2023.1193274"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbx108"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.210641.116"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1128\/aac.01572\u201017"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.736896"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.592291"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201024448\u20103"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkz028"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201004265\u2010w"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.621597"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz174"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469\u20100691.2011.03570.x"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1099\/acmi.0.000849.v2"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2024.1365011"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2024.07.059"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(21)02724\u20100"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.001193"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btv421"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/cpbi.102"},{"key":"e_1_2_11_51_1","volume-title":"QGIS Geographic Information System [WWW Document]","author":"QGIS Development Team","year":"2024"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens13110945"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2022.114075"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000206"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010\u2010024\u201002267\u20100"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00150"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000398"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu153"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu033"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2018.08.180"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41564\u2010022\u201001263\u20100"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000683"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.onehlt.2023.100516"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.02691\u201022"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201055103\u20102"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky492"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2016.09.007"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579\u2010019\u20100315\u20101"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1008114"}],"container-title":["Zoonoses and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/zph.70072","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/zph.70072","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/zph.70072","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T08:32:30Z","timestamp":1788337950000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/zph.70072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,15]]},"references-count":68,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/zph.70072"],"URL":"https:\/\/doi.org\/10.1111\/zph.70072","archive":["Portico"],"relation":{},"ISSN":["1863-1959","1863-2378"],"issn-type":[{"value":"1863-1959","type":"print"},{"value":"1863-2378","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,15]]},"assertion":[{"value":"2025-05-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}