{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T09:16:25Z","timestamp":1788340585067,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T00:00:00Z","timestamp":1782000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T00:00:00Z","timestamp":1782000000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["CEIRR 75N93021C00016"],"award-info":[{"award-number":["CEIRR 75N93021C00016"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["1241908"],"award-info":[{"award-number":["1241908"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["1241662"],"award-info":[{"award-number":["1241662"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["3260453"],"award-info":[{"award-number":["3260453"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020884","name":"Agencia Nacional de Investigaci\u00f3n y Desarrollo","doi-asserted-by":"publisher","award":["CIN250062"],"award-info":[{"award-number":["CIN250062"]}],"id":[{"id":"10.13039\/501100020884","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Influenza A virus (IAV) is a zoonotic pathogen with pandemic potential that infects a wide range of species, including companion animals. Although surveillance efforts have primarily focused on North America, Europe and Asia, data from South America remain scarce. This study evaluated the molecular and serological evidence of IAV circulation in dogs and cats from shelters and multi\u2010pet households in central Chile.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Between June and November 2020, oropharyngeal swabs and serum samples were collected from dogs and cats in shelters and multi\u2010pet households in central Chile. Samples were analysed by RT\u2010qPCR, NP\u2010ELISA and hemagglutination inhibition assay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>IAV was detected by RT\u2010qPCR in 3.2% (11\/342) of dogs (95% CI: 1.3%\u20135.1%) and 5.8% (4\/69) of cats (95% CI: 0.3%\u201311.3%). Serological analysis revealed IAV seropositivity in 55.5% (96\/173) of dogs (95% CI: 48.1%\u201362.9%) and 50.0% (10\/20) of cats (95% CI: 28.1%\u201371.9%). Additionally, pdmH1N1 antibodies were detected in 26 animals (25.7%; 95% CI: 17.2%\u201334.2%) out of 101 NP\u2010ELISA\u2010positive serum samples, with higher median titres for cats (median\u2009=\u2009160) compared to dogs (median\u2009=\u200920). Low\u2010level antibody titres against Canine\/H3N2 (range\u2009=\u200910\u201320) were identified in three dogs (3.0%; 95% CI: 0.0%\u20136.3%), whereas no antibodies were detected against Canine\/H3N8 or Avian\/H3N6. No significant associations were observed between seropositivity and animal age, sex, origin or area.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study presents the first report of IAV detection in cats in South America and highlights a high level of IAV exposure among companion animals in central Chile. These findings underscore the importance of including pets in IAV surveillance efforts under a One Health approach and highlight the need for expanded monitoring and genetic characterization of circulating strains to assess zoonotic risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/zph.70073","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T03:30:46Z","timestamp":1782099046000},"page":"528-535","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Serological and Molecular Surveillance of Influenza A Virus in Dogs and Cats in Central Chile"],"prefix":"10.1111","volume":"73","author":[{"given":"Cecilia","family":"Baumberger","sequence":"first","affiliation":[{"name":"Departamento de Medicina Preventiva, Facultad de Ciencias Veterinarias y Pecuarias Universidad de Chile  Santiago Chile"},{"name":"Escuela de Gobierno Pontificia Universidad Cat\u00f3lica de Chile  Santiago Chile"},{"name":"Surveillance, Epidemiology, and New Technologies for Infectious Emerging Threats (SENTINET)  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6662-0323","authenticated-orcid":false,"given":"Francisca","family":"Di Pillo","sequence":"additional","affiliation":[{"name":"N\u00facleo de Investigaci\u00f3n en One Health, Facultad de Medicina Veterinaria y Agronom\u00eda Universidad de Las Am\u00e9ricas  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Programa de Doctorado en Medicina de la Conservaci\u00f3n, Facultad de Ciencias de la Vida Universidad Andr\u00e9s Bello  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra","family":"Sep\u00falveda","sequence":"additional","affiliation":[{"name":"Departamento de Medicina Preventiva, Facultad de Ciencias Veterinarias y Pecuarias Universidad de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8633-8317","authenticated-orcid":false,"given":"Victor","family":"Marambio","sequence":"additional","affiliation":[{"name":"Departamento de Medicina Preventiva, Facultad de Ciencias Veterinarias y Pecuarias Universidad de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherinne","family":"Orozco","sequence":"additional","affiliation":[{"name":"Departamento de Medicina Preventiva, Facultad de Ciencias Veterinarias y Pecuarias Universidad de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9601-5471","authenticated-orcid":false,"given":"David","family":"Tapia","sequence":"additional","affiliation":[{"name":"Departamento de Medicina Preventiva, Facultad de Ciencias Veterinarias y Pecuarias Universidad de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5609-2237","authenticated-orcid":false,"given":"Christopher","family":"Hamilton\u2010West","sequence":"additional","affiliation":[{"name":"Departamento de Medicina Preventiva, Facultad de Ciencias Veterinarias y Pecuarias Universidad de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bridgett","family":"Sharp","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases St. Jude Children's Hospital  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey","family":"Schultz\u2010Cherry","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases St. Jude Children's Hospital  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6474-0804","authenticated-orcid":false,"given":"Pedro","family":"Jim\u00e9nez\u2010Bluhm","sequence":"additional","affiliation":[{"name":"Surveillance, Epidemiology, and New Technologies for Infectious Emerging Threats (SENTINET)  Santiago Chile"},{"name":"Escuela de Medicina Veterinaria, Facultad de Medicina, Facultad de Ciencias Biol\u00f3gicas, y Facultad de Agronom\u00eda y Sistemas Naturales Pontificia Universidad Cat\u00f3lica de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,21]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/v15040980"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2023.105426"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2010.0616.x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2020.00083"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2612.202063"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2908.230188"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani4030434"},{"key":"e_1_2_11_9_1","unstructured":"Di Rienzo J. A. F.Casanoves M. G.Balzarini L.Gonzalez M.Tablada andC. W.Robledo.2020.\u201cInfoStat Versi\u00f3n 2020. Centro de Transferencia InfoStat FCA Universidad Nacional de C\u00f3rdoba Argentina.\u201dhttp:\/\/www.infostat.com.ar."},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/v15030599"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1176225"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2401.171240"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2018.02.018"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2021.105349"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12412"},{"issue":"5","key":"e_1_2_11_16_1","first-page":"497","article-title":"Pandemic H1N1 Influenza Virus Infection in a Canadian Cat","volume":"57","author":"Knight C. 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