{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T11:44:34Z","timestamp":1792583074844,"version":"4.5.0"},"reference-count":38,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001824","name":"Grantov\u00e1 Agentura \u010cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["22\u201026136S"],"award-info":[{"award-number":["22\u201026136S"]}],"id":[{"id":"10.13039\/501100001824","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Zoonoses and Public Health"],"abstract":"ABSTRACT<\/jats:title>\n \n Introduction<\/jats:title>\n \n \n Angiostrongylus cantonensis<\/jats:italic>\n <\/jats:styled-content>\n is a zoonotic metastrongyloid nematode that causes eosinophilic meningitis and ocular angiostrongyliasis in humans and other accidental hosts. In India, reported human cases are sporadic, with several associated with monitor lizard consumption, while systematic studies remain limited.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We examined 60 opportunistically obtained rodent carcasses from six localities along the Pondicherry\u2010Tamil Nadu border. Molecular identification and phylogenetic analysis were performed on adult nematodes recovered from the rats.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n \n A.\u2009cantonensis<\/jats:italic>\n <\/jats:styled-content>\n was detected in three bandicoot rats, two\n \n Bandicota bengalensis<\/jats:italic>\n <\/jats:styled-content>\n and one\n \n B.\u2009indica<\/jats:italic>\n <\/jats:styled-content>\n . Parasite identity was confirmed by sequence analysis of the complete cytochrome c oxidase subunit I (\n cox1<\/jats:italic>\n ) gene, while rodent identity was confirmed using a partial cytochrome b (\n cytb<\/jats:italic>\n ) sequence. All eight recovered worms shared an identical\n cox1<\/jats:italic>\n sequence, representing the novel haplotype IND1. TN1 within Clade III.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n This study provides the first molecular confirmation of\n \n A.\u2009cantonensis<\/jats:italic>\n <\/jats:styled-content>\n in definitive hosts from India.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/zph.70100","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T11:20:13Z","timestamp":1792581613000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Revisiting a Neglected Zoonosis: Molecular Identification of\n Angiostrongylus cantonensis<\/i>\n in Southern Indian Rodents"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2084-4839","authenticated-orcid":false,"given":"Divakaran","family":"Pandian","sequence":"first","affiliation":[{"name":"Department of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources\/CINeZ Czech University of Life Sciences Prague Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8742-0216","authenticated-orcid":false,"given":"Lucia","family":"Anettov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources\/CINeZ Czech University of Life Sciences Prague Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4915-7263","authenticated-orcid":false,"given":"Barbora","family":"\u010cerven\u00e1","sequence":"additional","affiliation":[{"name":"Department of Pathology and Parasitology, Faculty of Veterinary Medicine University of Veterinary Sciences Brno Brno Czech Republic"},{"name":"Institute of Vertebrate Biology, Czech Academy of Sciences Brno Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2339-997X","authenticated-orcid":false,"given":"Chinnasamy","family":"Thirunavukkarasu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology Pondicherry University Puducherry India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2496-4034","authenticated-orcid":false,"given":"Vincenzo","family":"Veneziano","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Animal Productions University of Naples Federico II Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Modr\u00fd","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources\/CINeZ Czech University of Life Sciences Prague Czech Republic"},{"name":"Department of Botany and Zoology, Faculty of Science Masaryk University Brno Czech Republic"},{"name":"Institute of Parasitology, Biology Center of Czech Academy of Sciences \u010cesk\u00e9 Bud\u011bjovice Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,21]]},"reference":[{"issue":"5","key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1093\/sysbio\/syr041","article-title":"Survey of Branch Support Methods Demonstrates Accuracy, Power, and Robustness of Fast Likelihood\u2010Based Approximation Schemes","volume":"60","author":"Anisimova M.","year":"2011","journal-title":"Systematic Biology"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182020001262"},{"issue":"5","key":"e_1_2_11_4_1","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/QCO.0000000000000481","article-title":"Angiostrongylus cantonensis\n in Travelers: Clinical Manifestations, Diagnosis, and Treatment","volume":"31","author":"Ansdell V.","year":"2018","journal-title":"Current Opinion in Infectious Diseases"},{"key":"e_1_2_11_5_1","first-page":"1","article-title":"The Occurrence of \n Angiostrongylus cantonensis\n in Toads and Frogs in Okinawa Prefecture, Japan","volume":"27","author":"Asato R.","year":"1978","journal-title":"Japanese Journal of Parasitology"},{"issue":"6","key":"e_1_2_11_6_1","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.4269\/ajtmh.19-0701","article-title":"Two Ocular Angiostrongyliasis Cases in Thailand With Molecular Identification of Causative Parasite Species","volume":"102","author":"Boonroumkaew P.","year":"2020","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"2","key":"e_1_2_11_7_1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0166-6851(92)90109-W","article-title":"Genetic Variants Within the Genus Echinococcus Identified by Mitochondrial DNA Sequencing","volume":"54","author":"Bowles 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F.","year":"2001","journal-title":"Journal of Mammalian Evolution"},{"key":"e_1_2_11_12_1","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1111\/eva.12621","article-title":"Hurdles in the Evolutionary Epidemiology of Angiostrongylus cantonensis: Pseudogenes, Incongruence between Taxonomy and DNA Sequence Variants, and Cryptic Lineages","volume":"11","author":"Dusitsittipon S.","year":"2018","journal-title":"Evolutionary Applications"},{"key":"e_1_2_11_13_1","article-title":"Angiostrongylus cantonensis\n Central Nervous System Infection in Captive Callitrichids in Texas","volume":"19","author":"Edwards E. 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D.","year":"2025","journal-title":"Parasites & Vectors"},{"issue":"6","key":"e_1_2_11_16_1","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1038\/nmeth.4285","article-title":"ModelFinder: Fast Model Selection for Accurate Phylogenetic Estimates","volume":"14","author":"Kalyaanamoorthy S.","year":"2017","journal-title":"Nature Methods"},{"issue":"2","key":"e_1_2_11_17_1","first-page":"1","article-title":"Clinical Features of Eosinophilic Meningitis Caused by \n angiostrongylus cantonensis\n in Thailand: A Systematic Review","volume":"25","author":"Khamsai S.","year":"2020","journal-title":"Asia\u2010Pacific Journal of Science and Technology"},{"issue":"6","key":"e_1_2_11_18_1","first-page":"10","article-title":"Definitive, Intermediate, Paratenic, and Accidental Hosts of Angiostrongylus cantonensis and Its Molluscan Intermediate Hosts in Hawai\u02bbi","volume":"72","author":"Kim J. 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K.","year":"1992","journal-title":"International Journal for Parasitology"},{"issue":"3","key":"e_1_2_11_23_1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1093\/tropej\/fmi092","article-title":"Ocular Angiostrongyliasis in a Child\u2013First Case Report From India","volume":"52","author":"Malhotra S.","year":"2006","journal-title":"Journal of Tropical Pediatrics"},{"issue":"5","key":"e_1_2_11_24_1","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1442-9071.2006.01255.x","article-title":"Chemo\u2010Paralysis for the Removal of a Live Intraocular Worm in Ocular Angiostrongyliasis","volume":"34","author":"Mehta D. K.","year":"2006","journal-title":"Clinical & Experimental Ophthalmology"},{"issue":"5","key":"e_1_2_11_25_1","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1093\/molbev\/mst024","article-title":"Ultrafast Approximation for Phylogenetic Bootstrap","volume":"30","author":"Minh B. Q.","year":"2013","journal-title":"Molecular Biology and Evolution"},{"issue":"6","key":"e_1_2_11_26_1","doi-asserted-by":"crossref","DOI":"10.3390\/ani11061513","article-title":"Angiostrongylus Vasorum in Domestic Dogs in Castilla y Le\u00f3n, Iberian Peninsula, Spain","volume":"11","author":"Morch\u00f3n R.","year":"2021","journal-title":"Animals"},{"issue":"6","key":"e_1_2_11_27_1","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens12060851","article-title":"An Overview of \n Angiostrongylus cantonensis\n (Nematoda: Angiostrongylidae), an Emerging Cause of Human Angiostrongylosis on the Indian Subcontinent","volume":"12","author":"Pandian D.","year":"2023","journal-title":"Pathogens"},{"issue":"4","key":"e_1_2_11_28_1","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1017\/S0022149X00034751","article-title":"Prevalence of \n Angiostrongylus cantonensis\n Infection in Commensal Rats in Bombay","volume":"56","author":"Renapurkar D. M.","year":"1982","journal-title":"Journal of Helminthology"},{"key":"e_1_2_11_29_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.onehlt.2023.100628","article-title":"Fatal Neural Angiostrongyliasis in the Bolivian Squirrel Monkey (\n Saimiri boliviensis boliviensis\n ) Leading to Defining \n Angiostrongylus cantonensis\n Risk Map at a Zoo in Australia","volume":"17","author":"Rivory P.","year":"2023","journal-title":"One Health"},{"issue":"1","key":"e_1_2_11_30_1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/oxfordjournals.aje.a120673","article-title":"Studies on Eosinophilic Meningitis. 3. Epidemiologic and Clinical Observations on Pacific Islands and the Possible Etiologic Role of \n Angiostrongylus cantonensis","volume":"85","author":"Rosen L.","year":"1967","journal-title":"American Journal of Epidemiology"},{"issue":"2","key":"e_1_2_11_31_1","first-page":"38","article-title":"Study of a Focus of \n Angiostrongylus cantonensis\n in Greater Bombay","volume":"9","author":"Sharma K. D.","year":"1981","journal-title":"Bulletin of Haffkine Institute"},{"key":"e_1_2_11_32_1","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.2147\/OPTH.S204380","article-title":"Ocular Angiostrongyliasis in Thailand: A Retrospective Analysis Over Two Decades","volume":"13","author":"Sinawat S.","year":"2019","journal-title":"Clinical Ophthalmology"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens12060788"},{"issue":"1","key":"e_1_2_11_34_1","doi-asserted-by":"crossref","first-page":"W232","DOI":"10.1093\/nar\/gkw256","article-title":"W\u2010IQ\u2010TREE: A Fast Online Phylogenetic Tool for Maximum Likelihood Analysis","volume":"44","author":"Trifinopoulos J.","year":"2016","journal-title":"Nucleic Acids Research"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.onehlt.2022.100426"},{"issue":"2","key":"e_1_2_11_36_1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.4269\/ajtmh.25-0166","article-title":"Detecting \n Angiostrongylus cantonensis\n Eosinophilic Meningitis With Highly Sensitive Quantitative Polymerase Chain Reaction\u2010Report of Five Cases in Southern India","volume":"114","author":"Vinayan K. P.","year":"2025","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"issue":"6","key":"e_1_2_11_37_1","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/avj.12332","article-title":"Canine Neural Angiostrongylosis: A Case\u2013Control Study in Sydney Dogs","volume":"93","author":"Walker A. 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