{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T15:44:45Z","timestamp":1776527085250,"version":"3.51.2"},"reference-count":26,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T00:00:00Z","timestamp":1776470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T00:00:00Z","timestamp":1776470400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100032827","name":"Advanced Research and Invention Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100032827","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Allergy"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Medication availability and costs can be highly variable across countries and in different time periods. We aimed to conduct a survey among local experts to obtain information on the availability and costs of allergic rhinitis medications in different countries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We sent a survey to members of the Allergic Rhinitis and its Impact on Asthma (ARIA) group, asking for the availability and the lowest cost of specific allergic rhinitis medications in their respective countries. Data in local currencies were converted to 2024 US Dollars adjusted for Purchasing Power Parity (PPP). We compared the costs of different medication classes, assuming, for each class, the least expensive drug in each country, as well as full treatment adherence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We received responses from ARIA experts in 51 different countries. Intranasal corticosteroids (INCS) and oral antihistamines (OAH) were available in all countries, but this was not observed for intranasal antihistamines (INAH) or for INAH+INCS. In most countries, OAH was the least costly drug class, while INAH+INCS was the most expensive. Among INCS, beclomethasone was the medication most frequently identified as the cheapest, while cetirizine and loratadine were the OAH most frequently reported as the least expensive. Among INAH+INCS, azelastine\u2010fluticasone was more frequently identified as less costly than olopatadine\u2010mometasone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>There is an important across\u2010country and across\u2010class variability in terms of costs of allergic rhinitis medications. The results of this study will inform the ARIA\u2010EAACI 2024\u20132025 guidelines.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/all.70340","type":"journal-article","created":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T15:08:51Z","timestamp":1776524931000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Availability and Costs of Allergic Rhinitis Treatments Across the World: A Survey of\n                    <scp>ARIA<\/scp>\n                    Experts"],"prefix":"10.1111","author":[{"given":"Maria Clara","family":"Urbano","sequence":"first","affiliation":[{"name":"MEDCIDS\u2014Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto  Porto Portugal"},{"name":"CINTESIS@RISE \u2010 Centre for Health Technology and Services Research, Health Research Network, Faculty of Medicine University of Porto  Porto Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1834-3055","authenticated-orcid":false,"given":"Rafael Jos\u00e9","family":"Vieira","sequence":"additional","affiliation":[{"name":"MEDCIDS\u2014Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto  Porto Portugal"},{"name":"CINTESIS@RISE \u2010 Centre for Health Technology and Services Research, Health Research Network, Faculty of Medicine University of Porto  Porto Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3432-6837","authenticated-orcid":false,"given":"Yi\u2010Kui","family":"Xiang","sequence":"additional","affiliation":[{"name":"Institute of Allergology Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t Zu Berlin  Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP Immunology and Allergology  Berlin Germany"},{"name":"Shanghai Skin Disease Hospital, Tongji University School of Medicine  Shanghai China"}]},{"given":"Sara","family":"Gil\u2010Mata","sequence":"additional","affiliation":[{"name":"MEDCIDS\u2014Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto  Porto Portugal"},{"name":"CINTESIS@RISE \u2010 Centre for Health Technology and Services Research, Health Research Network, Faculty of Medicine University of Porto  Porto Portugal"}]},{"given":"Anna","family":"Bedbrook","sequence":"additional","affiliation":[{"name":"ARIA (Allergic Rhinitis and Its Impact on Asthma)  Montpellier France"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9138-9215","authenticated-orcid":false,"given":"Baharudin","family":"Abdullah","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, School of Medical Sciences Universiti Sains Malaysia  Kubang Kerian Kelantan Malaysia"}]},{"given":"Mona","family":"Al\u2010Ahmad","sequence":"additional","affiliation":[{"name":"Microbiology Department College of Medicine, Kuwait University  Kuwait City Kuwait"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9354-0214","authenticated-orcid":false,"given":"Maryam Ali","family":"Al\u2010Nesf","sequence":"additional","affiliation":[{"name":"Adult Allergy and Immunology Division Hamad Medical Corporation  Doha Qatar"}]},{"given":"Emilio","family":"Alvarez\u2010Cuesta","sequence":"additional","affiliation":[{"name":"Academic in Allergy and Immunology, Allergy Division Former Head, Ramon &amp; Cajal University Hospital  Madrid Spain"}]},{"given":"Salma Mussagy","family":"Amade","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Maputo Central Hospital  Maputo Mozambique"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1493-7101","authenticated-orcid":false,"given":"Julijana","family":"Asllani","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Medicine  Tirana Albania"}]},{"given":"Kazi S.","family":"Bennoor","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Institute of Diseases of the Chest and Hospital  Dhaka Bangladesh"}]},{"given":"Elena Camelia","family":"Berghea","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Carol Davila University of Medicine and Pharmacy  Bucharest Romania"},{"name":"Marie Curie Emergency Children's Hospital  Bucharest Romania"}]},{"given":"Mario","family":"Calvo\u2010Gil","sequence":"additional","affiliation":[{"name":"Pediatrics Department Universidad Austral de Chile  Valdivia Chile"}]},{"given":"Luis R.","family":"Caraballo","sequence":"additional","affiliation":[{"name":"Institute for Immunological 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