{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T20:03:13Z","timestamp":1774641793138,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,4,28]],"date-time":"2024-04-28T00:00:00Z","timestamp":1714262400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Small Animal Practice"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe the diagnostic tests used and their comparative performance in dogs diagnosed with sinonasal aspergillosis in the United Kingdom. A secondary objective was to describe the signalment, clinical findings and common clinicopathologic abnormalities in sinonasal aspergillosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A multi\u2010centre retrospective survey was performed involving 23 referral centres in the United Kingdom to identify dogs diagnosed with sinonasal aspergillosis from January 2011 to December 2021. Dogs were included if fungal plaques were seen during rhinoscopy or if ancillary testing (<jats:italic>via<\/jats:italic> histopathology, culture, cytology, serology or PCR) was positive and other differential diagnoses were excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 662 cases were entered into the database across the 23 referral centres. Four hundred and seventy\u2010five cases met the study inclusion criteria. Of these, 419 dogs had fungal plaques and compatible clinical signs. Fungal plaques were not seen in 56 dogs with turbinate destruction that\u00a0had compatible clinical signs and a positive ancillary test result. Ancillary diagnostics were performed in 312 of 419 (74%) dogs with observed fungal plaques permitting calculation of sensitivity\u00a0of cytology as 67%, fungal culture 59%, histopathology 47% and PCR 71%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>The sensitivities of ancillary diagnostics in this study were lower than previously reported challenging the clinical utility of such tests in sinonasal aspergillosis. Treatment and management decisions should be based on a combination of diagnostics including imaging findings, visual inspection, and ancillary testing, rather than ancillary tests alone.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jsap.13736","type":"journal-article","created":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T03:28:41Z","timestamp":1714361321000},"page":"622-630","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Diagnostic findings in sinonasal aspergillosis in dogs in the United Kingdom: 475 cases (2011\u20132021)"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5254-3205","authenticated-orcid":false,"given":"C.","family":"Prior","sequence":"first","affiliation":[{"name":"Willows Veterinary Centre and Referral Service, Part of Linnaeus Veterinary Limited  Solihull UK"}]},{"given":"H.","family":"Swales","sequence":"additional","affiliation":[{"name":"Moorview Referrals  Cramlington UK"}]},{"given":"M.","family":"Sharman","sequence":"additional","affiliation":[{"name":"VetCt  Cambridge UK"}]},{"given":"N.","family":"Reed","sequence":"additional","affiliation":[{"name":"Veterinary Specialists Scotland  Livingston UK"}]},{"given":"N.","family":"Bommer","sequence":"additional","affiliation":[{"name":"Veterinary Specialists Scotland  Livingston UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3680-5893","authenticated-orcid":false,"given":"A.","family":"Kent","sequence":"additional","affiliation":[{"name":"Blaise Veterinary Referral Hospital  Birmingham UK"}]},{"given":"B.","family":"Glanemann","sequence":"additional","affiliation":[{"name":"The Royal Veterinary College  London UK"}]},{"given":"K.","family":"Clarke","sequence":"additional","affiliation":[{"name":"Davies Veterinary Specialists  Hitchin UK"}]},{"given":"A.","family":"Kortum","sequence":"additional","affiliation":[{"name":"Cambridge Veterinary School  Cambridge UK"}]},{"given":"D.","family":"Kelly","sequence":"additional","affiliation":[{"name":"Southern Counties Veterinary Specialists  Ringwood UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8484-6796","authenticated-orcid":false,"given":"C.","family":"Lea","sequence":"additional","affiliation":[{"name":"Southern Counties Veterinary Specialists  Ringwood UK"}]},{"given":"E.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Bristol Veterinary Specialists  Bristol UK"}]},{"given":"L.","family":"Rutherford","sequence":"additional","affiliation":[{"name":"The Royal Veterinary College  London UK"}]},{"given":"A.","family":"Tamborini","sequence":"additional","affiliation":[{"name":"IDEXX Laboratories  Wetherby UK"}]},{"given":"K.","family":"Murphy","sequence":"additional","affiliation":[{"name":"Rowe Veterinary Referrals  Bristol UK"}]},{"given":"D. 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