{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:54:25Z","timestamp":1772160865605,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Allergy Immunology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Control of Allergic Rhinitis and Asthma Test for Children (CARATkids) is the first patient\u2010reported outcome measure (PROM) designed to assess both allergic rhinitis and asthma simultaneously in children aged 6 to 12\u2009years. CARATkids has been validated in several languages and countries, highlighting the need for a review of its psychometric properties. This study aims to evaluate the measurement properties of CARATkids. This systematic review follows PRISMA and COSMIN guidelines. A systematic search was performed across three databases (Ovid\/MEDLINE, Web of Science, and Scopus in October 2023, updated in June 2025). We included studies focused on the development, cultural adaptation, or validation of CARATkids, as well as studies comparing CARATkids with other PROMs. We evaluated the quality of CARATkids development, the methodological quality of primary studies, the overall rating, and the certainty of evidence for each CARATkids measurement property and performed a meta\u2010analysis of its measurement properties. Our search retrieved 193 results. We included nine studies. CARATkids displayed sufficient content validity. Regarding internal consistency, we found a meta\u2010analytical Cronbach alpha of 0.81 (95% CI\u2009=\u20090.79; 0.83). CARATkids displayed sufficient reliability (meta\u2010analytical intraclass correlation coefficient 0.86 [95% CI\u2009=\u20090.61; 0.96]). The minimal clinically important difference was 2.76. Construct validity had sufficient evidence for most correlations, with absolute meta\u2010analytical Spearman coefficients from 0.37 to 0.71. Responsiveness showed strong correlations between CARATkids and most outcome measurement instruments. These findings support CARATkids as a suitable tool for assessing asthma and allergic rhinitis in children aged 6 to 12\u2009years who present both conditions simultaneously.<\/jats:p>","DOI":"10.1111\/pai.70191","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T03:34:43Z","timestamp":1756870483000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Control of Allergic Rhinitis and Asthma Test for Children (\n                    <scp>CARATkids<\/scp>\n                    ): A systematic review and meta\u2010analysis of its measurement properties"],"prefix":"10.1111","volume":"36","author":[{"given":"Hadla Sami","family":"El Didi","sequence":"first","affiliation":[{"name":"Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, RISE\u2010Health University of Porto  Porto Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5468-0932","authenticated-orcid":false,"given":"Ana Margarida","family":"Pereira","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, RISE\u2010Health University of Porto  Porto Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1151-8791","authenticated-orcid":false,"given":"Cristina","family":"J\u00e1come","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, RISE\u2010Health University of Porto  Porto Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0233-830X","authenticated-orcid":false,"given":"Rita","family":"Amaral","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, RISE\u2010Health University of Porto  Porto Portugal"},{"name":"School of Health Polytechnic of Porto  Porto Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2173-4380","authenticated-orcid":false,"given":"Gustavo F.","family":"Wandalsen","sequence":"additional","affiliation":[{"name":"Escola Paulista de Medicina Universidade Federal de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}]},{"given":"Joyce","family":"Emons","sequence":"additional","affiliation":[{"name":"Division of Pediatric Respiratory Medicine and Allergology, Department of Pediatrics Erasmus MC University Medical Center  Rotterdam The Netherlands"}]},{"given":"Stefania","family":"La Grutta","sequence":"additional","affiliation":[{"name":"Institute of Translational Pharmacology National Research Council  Palermo Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4305-3981","authenticated-orcid":false,"given":"Giovanna","family":"Cilluffo","sequence":"additional","affiliation":[{"name":"Department of Earth and Marine Sciences, DiSTeM University of Palermo  Palermo Italy"},{"name":"CoNISMa National Inter\u2010University Consortium for Marine Sciences  Rome Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1913-5346","authenticated-orcid":false,"given":"Sehra Birg\u00fcl","family":"Batmaz","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy and Clinical Immunology Tokat State Hospital  Tokat Turkey"}]},{"given":"Daniela","family":"Linhares","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, RISE\u2010Health University of Porto  Porto Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3579-0861","authenticated-orcid":false,"given":"Dirceu","family":"Sole","sequence":"additional","affiliation":[{"name":"Escola Paulista de Medicina Universidade Federal de S\u00e3o Paulo  S\u00e3o Paulo 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