{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T14:55:25Z","timestamp":1786460125128,"version":"build-2736575974"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The objective is to systematically review the association between delirium and health effects in patients with neurological diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Delirium is a neuropsychiatric syndrome with acute brain dysfunction, characterized by fluctuating symptoms that affect cognition and consciousness. It is common in hospitalized patients, especially older patients and those with neurological conditions, and is associated with multiple poor health effects. However, recovery measured as health effects after delirium is unclear, and synthesis is needed to secure the best treatment for patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Eligibility criteria:<\/jats:title>\n                    <jats:p>This review will include observational studies that assess short- and long-term health effects after delirium in adult patients hospitalized for a principal diagnosis that is neurological. All delirium health effects will be investigated to assess the individual\u2019s recovery from delirium. The primary outcome is cognitive decline, and secondary outcomes are mortality and survival, functional decline, psychological outcomes, and health care utilization. Outcomes must be measured with validated scales.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This review will follow the JBI methodology for systematic reviews of etiology and risk and be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The search will be conducted in PubMed, Embase, CINAHL, PsycINFO, Cochrane Library, and Web of Science. No language restrictions will be applied. Two reviewers will independently perform study screening, selection, data extraction, and quality assessment. If applicable, meta-analysis will be conducted to assess the strength of the association between delirium and health effects. The results will be presented in tabular and graphical format, with a narrative summary.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Review registration:<\/jats:title>\n                    <jats:p>PROSPERO (CRD420251025893)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.11124\/jbies-24-00564","type":"journal-article","created":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T07:01:02Z","timestamp":1771916462000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Recovery after delirium in patients with neurological diseases: a systematic review protocol"],"prefix":"10.11124","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4474-4984","authenticated-orcid":false,"given":"Cecilie F.","family":"Jensen","sequence":"first","affiliation":[{"name":"Department of Neurology, Zealand University Hospital, Roskilde, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5389-1105","authenticated-orcid":false,"given":"Troels","family":"Wienecke","sequence":"additional","affiliation":[{"name":"Department of Neurology, Zealand University Hospital, Roskilde, Denmark"},{"name":"Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8008-6614","authenticated-orcid":false,"given":"Daniel","family":"H\u00e4gi-Pedersen","sequence":"additional","affiliation":[{"name":"Research Centre of Anaesthesiology and Intensive Care Medicine, Department of Anaesthesiology, N\u00e6stved, Slagelse and Ringsted Hospitals, Slagelse, Denmark"},{"name":"Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0342-017X","authenticated-orcid":false,"given":"Ingrid","family":"Poulsen","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, Copenhagen University Hospital, Amager Hvidovre, Hvidovre, Denmark"},{"name":"Roskilde University, Department for People and Technology, Roskilde, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0021-6242","authenticated-orcid":false,"given":"Janet F.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Zealand University Hospital, Roskilde, Denmark"},{"name":"Institute of Regional Health Research, University of Southern Denmark, Odense, 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