{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T14:57:03Z","timestamp":1786460223271,"version":"build-2736575974"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Objective:<\/jats:title>\n This systematic review will evaluate the costs and cost-effectiveness of robot-assisted pyeloplasty and laparoscopic pyeloplasty in patients with pelviureteric junction obstruction.<\/jats:p>\n <\/jats:sec>\n \n Introduction:<\/jats:title>\n Pelviureteric junction obstruction is the most common congenital abnormality of the urinary tract, affecting approximately 1 in every 1500 live births. Pyeloplasty is the standard treatment, with approaches including open, laparoscopic, and robot-assisted techniques. Though robotics offers advantages such as enhanced precision, concerns remain regarding its cost and cost-effectiveness compared to laparoscopic pyeloplasty, especially in resource-limited settings.<\/jats:p>\n <\/jats:sec>\n \n Eligibility criteria:<\/jats:title>\n The review will include studies involving pediatric and adult patients diagnosed with pelviureteric junction obstruction undergoing robot-assisted pyeloplasty or laparoscopic pyeloplasty. Studies focusing on outcomes related to resource utilization, costs, and cost-effectiveness for robot-assisted pyeloplasty and laparoscopic pyeloplasty, as well as cost analyses with and without comparators, will be included.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n The review will follow the JBI guidelines for the systematic review of economic evaluation evidence. A comprehensive search will be conducted among academic and non-academic databases and gray literature. Screening, data extraction, and critical appraisal will be conducted by 2 reviewers with adjudication by a third reviewer. Where feasible, meta-analyses will be performed using incremental net benefit for cost-effectiveness data; otherwise, findings will be presented as a narrative synthesis. JBI\u2019s Dominance Ranking Matrix for economic evaluations will be used to summarize and compare the results of cost-effectiveness studies. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach will be used to assess the certainty of economic evidence for outcomes related to resource use.<\/jats:p>\n <\/jats:sec>\n \n Review registration:<\/jats:title>\n PROSPERO CRD420251036657<\/jats:p>\n <\/jats:sec>","DOI":"10.11124\/jbies-25-00176","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T08:00:13Z","timestamp":1775635213000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Cost and cost-effectiveness of robotic-assisted pyeloplasty compared to laparoscopic pyeloplasty in patients with pelviureteric junction obstruction: a systematic review protocol"],"prefix":"10.11124","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9624-9999","authenticated-orcid":false,"given":"Nitinkumar","family":"Borkar","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, All India 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