{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T13:39:09Z","timestamp":1793281149143,"version":"4.5.0"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This systematic review aims to assess the prevalence and incidence of pressure injury associated with non-invasive ventilation in adult patients treated for acute respiratory failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Facial pressure sores are a common complication of non-invasive ventilation, impairing skin integrity, patient comfort, and therapy efficacy. However, the ranges of incidence and prevalence reported in the literature are wide.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Eligibility criteria:<\/jats:title>\n                    <jats:p>This review will include analytical observational and experimental studies reporting prevalence and\/or incidence of pressure sores in adults treated with non-invasive ventilation for hypoxemic or hypercapnic acute respiratory failure using oronasal, full-face, or hybrid masks. Any study or study arm testing interventions to reduce pressure sores will be excluded. Studies on pediatric patients and adult patients treated with other interfaces (ie, helmets) will also be excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This systematic review will be conducted in accordance with the JBI and PERSyst methodology for systematic reviews of prevalence and incidence. Searches will be conducted in PubMed, Cochrane Library, Web of Science, Embase, national health-agency surveillance systems, Centers for Disease Control and Prevention data, gray literature, and clinical trial registers to identify unpublished studies. No language limitations will be applied, provided an English abstract is available. Two reviewers will independently select studies, and data will be extracted using a customized form. Narrative synthesis will be conducted and, where appropriate, pooled prevalence and incidence proportion will be calculated using the DerSimonian and Laird method. Methodological quality will be assessed using JBI\u2019s Critical Appraisal Tool for Prevalence and Incidence Studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Review registration:<\/jats:title>\n                    <jats:p>PROSPERO CRD42024604191<\/jats:p>\n                  <\/jats:sec>","DOI":"10.11124\/jbies-25-00320","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T06:00:46Z","timestamp":1778133646000},"page":"1735-1742","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence and incidence of pressure injury in adult patients receiving non-invasive ventilation for acute respiratory failure: a systematic review protocol"],"prefix":"10.11124","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2940-9198","authenticated-orcid":false,"given":"Francesca","family":"Moretto","sequence":"first","affiliation":[{"name":"Universit\u00e0 degli Studi del Piemonte Orientale, Dipartimento di Medicina Traslazionale, Novara, Italy"},{"name":"Azienda Ospedaliero Universitaria \u201cMaggiore della Carit\u00e0\u201d, Anestesia e Terapia Intensiva, Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2583-6433","authenticated-orcid":false,"given":"Teresa","family":"Esposito","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi del Piemonte Orientale, Dipartimento di Medicina Traslazionale, Novara, Italy"},{"name":"Azienda Ospedaliero Universitaria \u201cMaggiore della Carit\u00e0\u201d, Anestesia e Terapia Intensiva, Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9297-5897","authenticated-orcid":false,"given":"Eduardo","family":"Rocca","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi del Piemonte Orientale, Dipartimento di Medicina Traslazionale, Novara, Italy"},{"name":"Azienda Ospedaliero Universitaria \u201cMaggiore della Carit\u00e0\u201d, Anestesia e Terapia Intensiva, Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3861-9058","authenticated-orcid":false,"given":"Lorenza","family":"Scotti","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi del Piemonte Orientale, Dipartimento di Medicina Traslazionale, Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6031-1271","authenticated-orcid":false,"given":"Erika","family":"Bassi","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi del Piemonte Orientale, Dipartimento di Medicina Traslazionale, Novara, Italy"},{"name":"Azienda Ospedaliero Universitaria \u201cMaggiore della Carit\u00e0\u201d, Direzione delle Professioni Sanitarie, Novara, Italy"},{"name":"JBI University of Piemonte Orientale for Healthy Aging, Vercelli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1609-3630","authenticated-orcid":false,"given":"Paolo","family":"Gardois","sequence":"additional","affiliation":[{"name":"Biblioteca Federata di Medicina \u201cFerdinando Rossi\u201d, Universit\u00e0 di Torino, Torino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2263-1340","authenticated-orcid":false,"given":"Alberto","family":"Dal Molin","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi del Piemonte Orientale, Dipartimento di Medicina Traslazionale, Novara, Italy"},{"name":"Azienda Ospedaliero Universitaria \u201cMaggiore della Carit\u00e0\u201d, Direzione delle Professioni Sanitarie, Novara, Italy"},{"name":"JBI University of Piemonte Orientale for Healthy Aging, Vercelli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4510-5212","authenticated-orcid":false,"given":"Francesco","family":"Musso","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi del Piemonte Orientale, Dipartimento di Medicina Traslazionale, Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9097-998X","authenticated-orcid":false,"given":"Luca","family":"Grillenzoni","sequence":"additional","affiliation":[{"name":"Medicina e Chirurgia d\u2019Urgenza e Accettazione, Nuovo Ospedale degli Infermi, Biella, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9088-5214","authenticated-orcid":false,"given":"Claudia","family":"Crimi","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy"},{"name":"Respiratory Intensive Care Unit, Policlinico \u201cG. 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Giglio Foundation, Cefal\u00f9, UniCamillus Medical School, Roma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2867-9193","authenticated-orcid":false,"given":"Giulia","family":"Sartori","sequence":"additional","affiliation":[{"name":"Department of Medicine, Respiratory Medicine Unit, University of Verona and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7298-7084","authenticated-orcid":false,"given":"Ernesto","family":"Crisafulli","sequence":"additional","affiliation":[{"name":"Department of Medicine, Respiratory Medicine Unit, University of Verona and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, 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