{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T03:20:08Z","timestamp":1787973608045,"version":"build-2784847793"},"reference-count":66,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T00:00:00Z","timestamp":1688688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001869","name":"Academia Sinica","doi-asserted-by":"publisher","award":["AS\u2010IA111\u2010L06"],"award-info":[{"award-number":["AS\u2010IA111\u2010L06"]}],"id":[{"id":"10.13039\/501100001869","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Physiology"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Proprioceptors are non\u2010nociceptive low\u2010threshold mechanoreceptors. However, recent studies have shown that proprioceptors are acid\u2010sensitive and express a variety of proton\u2010sensing ion channels and receptors. Accordingly, although proprioceptors are commonly known as mechanosensing neurons that monitor muscle contraction status and body position, they may have a role in the development of pain associated with tissue acidosis. In clinical practice, proprioception training is beneficial for pain relief. Here we summarize the current evidence to sketch a different role of proprioceptors in \u2018non\u2010nociceptive pain\u2019 with a focus on their acid\u2010sensing properties.<\/jats:p>","DOI":"10.1113\/ep090989","type":"journal-article","created":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T07:58:49Z","timestamp":1688716729000},"page":"45-54","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Role of proprioceptors in chronic musculoskeletal pain"],"prefix":"10.1113","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3642-4115","authenticated-orcid":false,"given":"Cheng\u2010Han","family":"Lee","sequence":"first","affiliation":[{"name":"Institute of Biomedical Sciences Academia Sinica Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4768-5660","authenticated-orcid":false,"given":"Chih\u2010Cheng","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Sciences Academia Sinica Taipei Taiwan"},{"name":"Neuroscience Program of Academia Sinica Academia Sinica Taipei Taiwan"},{"name":"Taiwan Mouse Clinic, Biomedical Translational Research Center Academia Sinica Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.125161"},{"issue":"12","key":"e_1_2_9_3_1","first-page":"1","article-title":"Complementary and alternative medicine use among adults and children: United States, 2007","volume":"10","author":"Barnes P. 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