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Women living with obesity\/overweight are more susceptible to these changes causing complications such as gestational diabetes. This is particularly worrying as up to 60% of European women are living with overweight\/obesity at the onset of pregnancy. Furthermore, less than 1% meet all nutrition guidelines. There is now evidence that these deep metabolic changes can result in a predisposition to metabolic disease in both the mother and child in later life. Health and nutrition status during this period therefore represents a window to future health. This period offers a valuable opportunity for intervention to prevent the negative consequences of poor in utero environments and increases the long\u2010term quality of life for mother and offspring. This review will examine a range of in utero factors which determine adipose tissue development, the impact of these factors on later\u2010life obesity and metabolic health and the therapeutic value of dietary anti\u2010inflammatory nutritional interventions during pregnancy and early life. When it comes to early life nutrition, a \u2018one size fits all\u2019 approach is not always appropriate. Understanding the mechanisms of adipose tissue development in response to differing nutritional strategies may be important in the context of complicated or adverse in utero environments and represents a substantial step towards a more personalised nutritional approach for the prevention of obesity, metabolic syndrome and related non\u2010communicable diseases in future generations.<\/jats:p>","DOI":"10.1113\/ep091209","type":"journal-article","created":{"date-parts":[[2023,11,30]],"date-time":"2023-11-30T09:40:59Z","timestamp":1701337259000},"page":"633-646","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Developmentally programmed obesity: Is there a role for anti\u2010inflammatory nutritional strategies?"],"prefix":"10.1113","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5782-6303","authenticated-orcid":false,"given":"Michelle 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