{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:55:56Z","timestamp":1791824156346,"version":"4.3.4"},"reference-count":57,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T00:00:00Z","timestamp":1722556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T00:00:00Z","timestamp":1722556800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Physiology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Sitting\u2010induced impairments in postprandial blood flow are an important link between sedentary behaviour and cardiometabolic disease risk. The objective of this work was to examine the effects of resistance exercise breaks (REB) performed every 30\u00a0min during an otherwise sedentary 3\u2010h period on the vasodilatory response to a subsequent oral glucose load in sedentary adults. Twenty\u2010four sedentary adults (27\u00a0\u00b1\u00a07 years, 16 females) completed two conditions.\u00a0Fasting blood glucose, insulin, popliteal artery blood flow (PABF) and gastrocnemius perfusion were measured immediately before standardized breakfast consumption. After breakfast, the 3\u2010h REB or uninterrupted (SIT) intervention period commenced. Participants sat at a workstation, and popliteal artery shear rate (PASR) was measured 60 and 120\u00a0min into this period. In the REB condition, participants performed a 3\u2010min REB (3 \u00d7 [20\u00a0s squats, 20\u00a0s high knees, 20\u00a0s calf raises]) every 30\u00a0min. Following the intervention period, baseline measurements were repeated. Participants then consumed a 75\u00a0g glucose beverage, and PABF and perfusion were measured every 30\u201360\u00a0min for the following 120\u00a0min. Relative to SIT, REB increased PASR at 60\u00a0min (+31.4\u00a0\u00b1\u00a09.2\/s,\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    =\u00a00.037) and 120\u00a0min (+37.4\u00a0\u00b1\u00a010.2\/s,\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    =\u00a00.019) into the intervention period. Insulin and glucose increased (\n                    <jats:italic>P\u00a0&lt;<\/jats:italic>\n                    \u00a00.001) in response to glucose consumption, with no differences between conditions (\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    \u2265\u00a00.299). In response to the glucose load, perfusion (1.57\u00a0vs. 1.11\u00a0mL\/100\u00a0mL\/min,\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    =\u00a00.023) and PABF (+45.3\u00a0\u00b1\u00a011.8\u00a0mL\/min,\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    =\u00a00.001) were greater after REB versus SIT. Performing 3\u2010min REB every 30\u00a0min during an otherwise sedentary 3\u2010h period augmented leg blood flow responses to an oral glucose load.\n                  <\/jats:p>","DOI":"10.1113\/ep091535","type":"journal-article","created":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T10:43:23Z","timestamp":1722595403000},"page":"3082-3098","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Resistance exercise breaks during prolonged sitting augment the blood flow response to a subsequent oral glucose load in sedentary adults"],"prefix":"10.1113","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2643-2904","authenticated-orcid":false,"given":"Emily M.","family":"Rogers","sequence":"first","affiliation":[{"name":"Department of Health and Human Physiology The University of Iowa  Iowa City Iowa USA"},{"name":"Department of Kinesiology The University of Wisconsin  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2110-9163","authenticated-orcid":false,"given":"Nile F.","family":"Banks","sequence":"additional","affiliation":[{"name":"Department of Health and Human Physiology The University of Iowa  Iowa City Iowa USA"},{"name":"Department of Kinesiology The University of Wisconsin  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma R.","family":"Trachta","sequence":"additional","affiliation":[{"name":"Department of Health and Human Physiology The University of Iowa  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgan S.","family":"Wolf","sequence":"additional","affiliation":[{"name":"Department of Health and Human Physiology The University of Iowa  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander C.","family":"Berry","sequence":"additional","affiliation":[{"name":"Department of Health and Human Physiology The University of Iowa  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3941-3879","authenticated-orcid":false,"given":"Anna E.","family":"Stanhewicz","sequence":"additional","affiliation":[{"name":"Department of Health and Human Physiology The University of Iowa  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas J.","family":"Carr","sequence":"additional","affiliation":[{"name":"Department of Health and Human Physiology The University of Iowa  Iowa City Iowa USA"},{"name":"Fraternal Order of Eagles Diabetes Research Center The University of Iowa  Iowa City USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bethany Barone","family":"Gibbs","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics West Virginia University School of Public Health  Morgantown West Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1781-3414","authenticated-orcid":false,"given":"Nathaniel D. 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