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Although cardiopulmonary responses have seldom been reported in conjunction with ST, this repeated\u2010measurement study examined acute blood pressure and haemodynamic responses continuously depending on the number of repetitions but without changing the intensity. Fifteen healthy male participants (21.6 (2.0)\u00a0years; mean (SD)) performed an incremental exercise test and a 3\u2010repetition maximum test (3\u2010RM) on a Smith machine. They were then randomly assigned to three ST sessions involving 10, 20 and 30 repetitions at 50% of their 3\u2010RM. Blood pressure (vascular unloading technique) and cardiopulmonary responses (spirometry and impedance cardiography) were continuously monitored. Heart rate (121 (10) vs. 139 (22) vs. 153 (13) bpm, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.001, respectively), cardiac output (10.4 (1.9) vs. 13.6 (3.8) vs. 14.6 (3.1) L\/min, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.001, respectively) and diastolic blood pressure (113 (8) vs. 116 (21) vs. 135 (22) mmHg, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.001, respectively) increased in the training sessions with higher repetitions. Stroke volume, systolic blood pressure and end\u2010diastolic volume indicated no change in peak values between training sessions. Total peripheral resistance (13.6 (2.8) vs. 11.3 (3.6) vs. 11.2 (3.1) mmHg\u00a0min\/L, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.002, respectively) was significantly lower with 20 and 30 repetitions, while oxygen uptake (: 15.5 (1.9) vs. 20.5 (4.1) vs. 20.6 (4.4) mL\/min\/kg, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.001, respectively) was significantly higher. ST of moderate intensity with an exhausting number (&gt;20) of repetitions induces strong haemodynamic responses, especially high cardiac afterload and a compensatory heart rate acceleration, which may also create a strong stimulus for cardiopulmonary adaptation.<\/jats:p>","DOI":"10.1113\/ep092363","type":"journal-article","created":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T03:41:01Z","timestamp":1740195661000},"page":"1114-1128","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Repetition\u2010dependent acute cardiopulmonary responses during intensity\u2010matched squats in males"],"prefix":"10.1113","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6109-4061","authenticated-orcid":false,"given":"Johannes","family":"L\u00e4ssing","sequence":"first","affiliation":[{"name":"Department of Exercise Science &amp; Sports Medicine Martin Luther University Halle\u2010Wittenberg  Halle (Saale) Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonja","family":"Hummelmann","sequence":"additional","affiliation":[{"name":"Institute of Sports Medicine and Prevention University of Leipzig  Leipzig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxi","family":"Kramer","sequence":"additional","affiliation":[{"name":"Institute of Sports Medicine and Prevention University of Leipzig  Leipzig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Laufs","sequence":"additional","affiliation":[{"name":"University Leipzig, Medizinische Fakult\u00e4t  Leipzig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Fikenzer","sequence":"additional","affiliation":[{"name":"University Leipzig, Medizinische Fakult\u00e4t  Leipzig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9956-7538","authenticated-orcid":false,"given":"Roberto","family":"Falz","sequence":"additional","affiliation":[{"name":"Institute of Sports Medicine and Prevention University of Leipzig  Leipzig Germany"},{"name":"Human\u2012Machine\u2010Interaction Magdeburg\u2010Stendal University of Applied Science  Magdeburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1099800420958068"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-021-04656-x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004210050063"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02337176"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1113\/EP085368"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-002-0681-6"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1139\/apnm-2021-0515"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004210000226"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-19269"},{"key":"e_1_2_10_11_1","volume-title":"Statistical power analysis for the behavioral sciences","author":"Cohen J.","year":"1988"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.07.105"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(05)80033-6"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.2165\/11315230-000000000-00000"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/2047487313497863"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2021-104642"},{"issue":"12","key":"e_1_2_10_17_1","first-page":"809","article-title":"[Pressure\u2010dimension analysis of the poststimulation potentiation\u2013influence of heart rate and ventricular function (author's transl)]","volume":"68","author":"Erbel R.","year":"1979","journal-title":"Zeitschrift Fur Kardiologie"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0739(17)30748-4"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-019-04138-1"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.91497.2007"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000436752.99896.22"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1139\/h2012-109"},{"issue":"5","key":"e_1_2_10_23_1","first-page":"616","article-title":"Acute hemodynamic and cardiovascular responses following resistance exercise to voluntary exhaustion. 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