{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:58:42Z","timestamp":1790312322300,"version":"4.1.0"},"reference-count":58,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T00:00:00Z","timestamp":1753488000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T00:00:00Z","timestamp":1753488000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Physiology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Because obesity and related diseases are partly attributed to unrestricted consumption of a high\u2010fat, high\u2010sugar Western diet (WD), several studies have examined its adverse effects on health and physical fitness. However, short\u2010term WD supplementation has received little attention. We asked whether such supplementation can improve the aerobic exercise performance of animals with inherently distinct aerobic capacity. We used bank voles [\n                    <jats:italic>Clethrionomys<\/jats:italic>\n                    (=\u00a0\n                    <jats:italic>Myodes<\/jats:italic>\n                    )\n                    <jats:italic>glareolus<\/jats:italic>\n                    ] from lines selected for high swim\u2010induced aerobic metabolism (A) and unselected control lines (C). In a crossover design, we measured endurance running distance, aerobic capacity (), peak speed (\n                    <jats:italic>V<\/jats:italic>\n                    <jats:sub>max<\/jats:sub>\n                    ) and respiratory exchange ratio in 98 animals fed standard rodent diet (14.5\u00a0kJ\/g) or WD (20.5\u00a0kJ\/g; 48% from carbohydrates, including 28% from added sucrose, and 39% from fat) for 2 days before the trials. The ,\n                    <jats:italic>V<\/jats:italic>\n                    <jats:sub>max<\/jats:sub>\n                    and endurance distance were higher in A lines than in C lines. In A lines, endurance distance increased with\n                    <jats:italic>V<\/jats:italic>\n                    <jats:sub>max<\/jats:sub>\n                    but not with , whereas in C lines it increased more with  than with\n                    <jats:italic>V<\/jats:italic>\n                    <jats:sub>max<\/jats:sub>\n                    . The WD treatment resulted in increased body mass (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.006) and did not affect  (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.4), but tended to decrease\n                    <jats:italic>V<\/jats:italic>\n                    <jats:sub>max<\/jats:sub>\n                    (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.04), endurance distance (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.099), mass loss during the trials (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.008) and, in A lines only, the respiratory exchange ratio (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.02). These results show that the selection experiment provides a model of genetically distinct aerobic athletes and non\u2010athletes, in whom exercise performance appears to be limited by different mechanisms. Regardless of the genetic background, short\u2010term WD supplementation does not improve aerobic exercise performance and reduces the effectiveness of exercise as a method of weight loss.\n                  <\/jats:p>","DOI":"10.1113\/ep092646","type":"journal-article","created":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T18:24:29Z","timestamp":1753554269000},"page":"930-945","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The effects of short\u2010term consumption of a Western diet on aerobic exercise performance in bank voles with inherently distinct metabolic rates"],"prefix":"10.1113","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1472-6411","authenticated-orcid":false,"given":"Alaa","family":"Hseiky","sequence":"first","affiliation":[{"name":"Institute of Environmental Sciences, Faculty of Biology Jagiellonian University  Krak\u00f3w Poland"},{"name":"Doctoral School of Exact and Natural Sciences Jagiellonian University  Krakow Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1240-4814","authenticated-orcid":false,"given":"Edyta T.","family":"Sadowska","sequence":"additional","affiliation":[{"name":"Institute of Environmental Sciences, Faculty of Biology Jagiellonian University  Krak\u00f3w Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0077-4957","authenticated-orcid":false,"given":"Pawe\u0142","family":"Koteja","sequence":"additional","affiliation":[{"name":"Institute of Environmental Sciences, Faculty of Biology Jagiellonian University  Krak\u00f3w Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.beproc.2016.11.018"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-018-0941-1"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2019.1568322"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200001000-00012"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13256"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu10081109"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00442-020-04704-x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aau2093"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200201000-00014"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13082896"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40200-015-0154-1"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40064-016-3508-3"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn.81.2.341"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13082506"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1123\/ijsnem.15.1.1"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2020.04.017"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1152\/physiolgenomics.00077.2015"},{"key":"e_1_2_10_19_1","first-page":"114","article-title":"Circulatory endotoxin concentration and cytokine profile in response to exertional\u2010heat stress during a multi\u2010stage ultra\u2010marathon competition","volume":"21","author":"Gill S. 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