{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:56:06Z","timestamp":1783644966007,"version":"3.55.0"},"reference-count":52,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Physiology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Assessment of near\u2010infrared spectroscopy (NIRS)\u2010derived muscle oxidative capacity relies on analysing deoxygenation slopes from NIRS signal versus time curves during brief arterial occlusions, which reflect the rate of post\u2010exercise recovery of muscle oxygen consumption (). However, current guidelines lack recommendations on the optimal selection of slopes for reliable measurement. The aim of the study was to compare a standardised partial\u2010segment approach against the conventional whole\u2010segment approach on the measurement and reliability of in vivo muscle oxidative capacity. Within the same session, 19 athletes (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a09 sprinters;\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a010 middle\u2010distance runners) completed two NIRS\u2010derived muscle oxidative capacity trials on the vastus lateralis. Rate constants (\n                    <jats:italic>k<\/jats:italic>\n                    , min\n                    <jats:sup>\u22121<\/jats:sup>\n                    ) were computed using the steepest (), whole () or shallowest () deoxygenation slope from deoxyhaemoglobin (HHb) and muscle O\n                    <jats:sub>2<\/jats:sub>\n                    saturation () signals. Test\u2013retest reliability [(coefficient of variation (CV), intraclass correlation coefficient (ICC)] and minimum difference (MD) were assessed. For the HHb signal, ICC analysis revealed moderate to excellent test\u2013retest reliability for  [0.80 (0.54\u20130.92)], whereas poor to good reliability was observed for  [0.71 (0.38\u20130.89)] and  [0.60 (0.19\u20130.83)].  led to lower MD compared to  and  (0.64 vs. 1.12 vs. 1.54\u00a0min\n                    <jats:sup>\u22121<\/jats:sup>\n                    , respectively). All three approaches led to significantly greater\n                    <jats:italic>k<\/jats:italic>\n                    values in runners compared to sprinters (:+32.2%,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u00a00.001; :+ 40.1%,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.025; :+49.6%,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.001). Compared to the conventional whole\u2010segment approach, selecting the steepest intra\u2010occlusion slope improved the reliability and sensitivity of NIRS\u2010derived mitochondrial capacity, likely by better reflecting instantaneous changes in .\n                  <\/jats:p>","DOI":"10.1113\/ep093040","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T11:52:22Z","timestamp":1765540342000},"page":"1150-1164","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Steepest near\u2010infrared spectroscopy\u2010derived deoxygenation slopes during arterial occlusions provide more reliable assessments of muscle mitochondrial capacity"],"prefix":"10.1113","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0478-2882","authenticated-orcid":false,"given":"Guillaume","family":"Costalat","sequence":"first","affiliation":[{"name":"Faculty of Sport Sciences, APERE laboratory, UR\u2010UPJV 3300 University of Picardie Jules Verne  Amiens France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beno\u00eet","family":"Sautillet","sequence":"additional","affiliation":[{"name":"Faculty of Sport Sciences, APERE laboratory, UR\u2010UPJV 3300 University of Picardie Jules Verne  Amiens France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8081-4423","authenticated-orcid":false,"given":"Gr\u00e9goire P.","family":"Millet","sequence":"additional","affiliation":[{"name":"Institute of Sport Sciences University of Lausanne  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9ment","family":"Unal","sequence":"additional","affiliation":[{"name":"Faculty of Sport Sciences, APERE laboratory, UR\u2010UPJV 3300 University of Picardie Jules Verne  Amiens 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