{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T09:28:46Z","timestamp":1793611726659,"version":"4.5.0"},"reference-count":66,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Physiology"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Exercise maintains brain health and reduces the risk of cerebrovascular diseases, such as stroke and dementia. The benefits of different \u2018modalities\u2019 of exercise on male and female cerebral autoregulation are unclear. In this study, we compared adaptations in dynamic cerebral autoregulation (dCA) during spontaneous and forced oscillations in blood pressure between males and females following endurance (END) and resistance (RES) training. Using a randomized cross\u2010over design, 49 healthy adults were recruited to participate in 3\u00a0months of END and RES training, with 3\u00a0months of washout. Middle cerebral artery blood velocity (MCAv) was measured using transcranial Doppler. The dCA was assessed using spontaneous (at rest) and forced oscillations in blood pressure (squat\u2013stands) in the low\u2010frequency band (0.167 and 0.083\u00a0Hz). At baseline, females had lower end\u2010tidal partial pressure of CO\n                    <jats:sub>2<\/jats:sub>\n                    , higher MCAv and higher gain than males (all\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    &lt;\u00a00.01). On a group level, there was a significant reduction in gain following RES but not END training during spontaneous dCA and forced dCA (all\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    &lt;\u00a00.05). When sexes were analysed separately, this reduction was apparent in females, but not in males. Furthermore, females had a significant reduction in normalized gain during spontaneous dCA and forced dCA at 0.167\u00a0Hz. This study is the first to assess sex differences in dCA using a randomized cross\u2010over design involving supervised exercise of two distinct modalities. We found that RES training might be more beneficial than END training for improving dCA in young healthy individuals, and this is apparent across multiple methods of measuring dCA. This benefit is more apparent in females.\n                  <\/jats:p>","DOI":"10.1113\/ep093183","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T15:52:46Z","timestamp":1771429966000},"page":"5250-5264","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Sex differences in dynamic cerebral autoregulation responses to resistance and endurance training in humans"],"prefix":"10.1113","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7885-5218","authenticated-orcid":false,"given":"Hannah J.","family":"Thomas","sequence":"first","affiliation":[{"name":"School of Human Sciences, Exercise and Sport Science The University of Western Australia  Perth Western Australia Australia"},{"name":"Institute for Health and Sport Victoria University  Footscray Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Channa E.","family":"Marsh","sequence":"additional","affiliation":[{"name":"School of Human Sciences, Exercise and Sport Science The University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leanne","family":"Lester","sequence":"additional","affiliation":[{"name":"School of Human Sciences, Exercise and Sport Science The University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6210-912X","authenticated-orcid":false,"given":"Louise H.","family":"Naylor","sequence":"additional","affiliation":[{"name":"School of Human Sciences, Exercise and Sport Science The University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8914-6457","authenticated-orcid":false,"given":"Kurt J.","family":"Smith","sequence":"additional","affiliation":[{"name":"Cerebrovascular Health, Exercise, and Environmental Research Sciences Laboratory, Exercise Science, Physical &amp; Health Education University of Victoria  Victoria British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3226-2921","authenticated-orcid":false,"given":"Daniel J.","family":"Green","sequence":"additional","affiliation":[{"name":"School of Human Sciences, Exercise and Sport Science The University of Western Australia  Perth Western Australia 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