{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:24:22Z","timestamp":1792131862695,"version":"4.4.0"},"reference-count":50,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Physiology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Even among healthy individuals, arterial blood pressure (ABP) responses to exercise vary widely. However, the mechanisms underlying this individual variability remain unclear. To investigate these mechanisms, 29 participants performed isometric handgrip exercise at 30% of their maximum voluntary contraction, followed by postexercise muscle ischaemia to assess metaboreflex activity. The systolic blood pressure response to exercise was not significantly correlated with arterial stiffness (carotid\u2013femoral pulse wave velocity,\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.999, \u03b2\u00a0=\u00a00.000), peak oxygen uptake (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.224, \u03b2\u00a0=\u00a00.168) or muscle oxidative capacity (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.829, \u03b2\u00a0=\u00a0\u22120.049). In contrast, individual variability in systolic blood pressure was significantly associated with variability in heart rate during exercise (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.013, \u03b2\u00a0=\u00a00.360) and the change in mean arterial pressure during postexercise muscle ischaemia (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.014, \u03b2\u00a0=\u00a00.692). These findings suggest that peripheral characteristics are not primary determinants of individual differences in ABP responses to exercise in healthy young adults. Instead, variability in ABP responses might be more strongly influenced by individual differences in autonomic function. This pattern contrasts with the mechanisms underlying exaggerated ABP responses commonly observed in older adults and individuals with hypertension.\n                  <\/jats:p>","DOI":"10.1113\/ep093208","type":"journal-article","created":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T17:42:51Z","timestamp":1764178971000},"page":"727-737","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Exploring physiological factors underlying individual differences in exercise\u2010induced blood pressure responses"],"prefix":"10.1113","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5297-6468","authenticated-orcid":false,"given":"Shigehiko","family":"Ogoh","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering Toyo University  Asaka Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6535-0912","authenticated-orcid":false,"given":"Ryosuke","family":"Takeda","sequence":"additional","affiliation":[{"name":"Laboratory of Neuromuscular Biomechanics, School of Health and Sport Sciences Chukyo University  Toyota Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narumi","family":"Kunimatsu","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering Toyo University  Asaka Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5512-0497","authenticated-orcid":false,"given":"Hayato","family":"Tsukamoto","sequence":"additional","affiliation":[{"name":"Faculty of Sport Sciences Waseda University Tokorozawa Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai","family":"Shimada","sequence":"additional","affiliation":[{"name":"Faculty of Sport and Health Sciences Osaka Sangyo University Daito Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoki","family":"Watada","sequence":"additional","affiliation":[{"name":"Faculty of Sport and Health Sciences Osaka Sangyo University Daito Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6610-1891","authenticated-orcid":false,"given":"Marina","family":"Feeley","sequence":"additional","affiliation":[{"name":"Faculty of Sport and Health Sciences Osaka Sangyo University Daito Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taichi","family":"Nishikawa","sequence":"additional","affiliation":[{"name":"Laboratory of Neuromuscular Biomechanics, School of Health and Sport Sciences Chukyo University  Toyota Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marino","family":"Karaki","sequence":"additional","affiliation":[{"name":"Laboratory of 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