{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T05:04:07Z","timestamp":1784783047532,"version":"3.55.0"},"reference-count":84,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008749","name":"American College of Sports Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008749","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Physiology"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We compared the acute and chronic effects of postexercise cold water immersion (CWI) and active recovery (ACT) on oxidative stress, redox\u2010related gene expression, mitochondrial adaptations and muscle oxidative capacity. In a crossover study, nine males completed strength sessions, followed by either 10\u00a0min CWI or ACT. There were time effects for blood oxidative stress markers, including serum derivatives of reactive oxygen metabolites and serum biological antioxidant potential (\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    &lt;\u00a00.05). F\n                    <jats:sub>2<\/jats:sub>\n                    \u2010Isoprostanes were lower after exercise in the CWI trial compared with the ACT trial (\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    &lt;\u00a00.05), whereas plasma glutathione peroxidase activity was higher in the CWI trial at 2\u00a0h after exercise (\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    &lt;\u00a00.05). There were time effects for redox\u2010related genes, including\n                    <jats:italic>NRF2<\/jats:italic>\n                    ,\n                    <jats:italic>SXRN<\/jats:italic>\n                    ,\n                    <jats:italic>HMOX1<\/jats:italic>\n                    ,\n                    <jats:italic>GCLM<\/jats:italic>\n                    ,\n                    <jats:italic>TP53<\/jats:italic>\n                    and\n                    <jats:italic>TXN<\/jats:italic>\n                    , in muscle after exercise (\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    &lt;\u00a00.05). Postexercise gene expression did not differ between the CWI and ACT trials. In a parallel\u2010group study, 21 males strength\u2010trained twice a week for 3 months and performed either 10\u00a0min CWI or ACT after each session. There were time effects for the activity of citrate synthase and mitochondrial enzyme complexes I and IV (\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    &lt;\u00a00.05) and the protein abundance of p\u2010AMPK (\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    &lt;\u00a00.05) in muscle after training. These responses did not differ between the CWI and ACT groups. Evaluation of muscle oxidative capacity using near\u2010infrared spectroscopy showed slower oxygen desaturation during a 10\u00a0s isometric contraction, and greater oxygen consumption during 50 isokinetic contractions after training in the CWI group (\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    &lt;\u00a00.05). In conclusion, CWI after resistance exercise does not alter acute redox\u2010related transcription or chronic mitochondrial adaptations, whereas it might improve muscle oxygen kinetics.\n                  <\/jats:p>","DOI":"10.1113\/ep093660","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T04:43:15Z","timestamp":1784781795000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of cold water immersion versus active recovery on oxidative stress, redox gene expression and mitochondrial adaptations after strength training"],"prefix":"10.1113","author":[{"given":"Llion A.","family":"Roberts","sequence":"first","affiliation":[{"name":"School of Human Movement and Nutrition Sciences The University of Queensland  Brisbane Queensland Australia"},{"name":"Australian Centre for Precision Health and Technology (PRECISE) School of Allied Health, Sport and Social Work Griffith University  Gold Coast Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal A.","family":"Pileggi","sequence":"additional","affiliation":[{"name":"Liggins Institute The University of Auckland  Auckland New Zealand"},{"name":"Department of Biochemistry, Microbiology and Immunology University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Zeng","sequence":"additional","affiliation":[{"name":"Liggins Institute The University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vandre C.","family":"Figueiredo","sequence":"additional","affiliation":[{"name":"Liggins Institute The University of Auckland  Auckland New Zealand"},{"name":"Department of Biological Sciences Oakland University  Rochester Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James F.","family":"Markworth","sequence":"additional","affiliation":[{"name":"Liggins Institute The University of Auckland  Auckland New Zealand"},{"name":"Department of Animal Science Purdue University  West Lafayette Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Truls","family":"Raastad","sequence":"additional","affiliation":[{"name":"Norwegian School of Sport Sciences  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Briskey","sequence":"additional","affiliation":[{"name":"School of Human Movement and Nutrition Sciences The University of Queensland  Brisbane Queensland Australia"},{"name":"RDC Global  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6572-5809","authenticated-orcid":false,"given":"Katsuhiko","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Faculty of Sport Sciences Waseda University  Tokorozawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeff S.","family":"Coombes","sequence":"additional","affiliation":[{"name":"School of Human Movement and Nutrition Sciences The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0144-5816","authenticated-orcid":false,"given":"David","family":"Cameron\u2010Smith","sequence":"additional","affiliation":[{"name":"Liggins Institute The University of Auckland  Auckland New Zealand"},{"name":"Riddet Institute Massey University  Palmerston North New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8218-0038","authenticated-orcid":false,"given":"Jonathan M.","family":"Peake","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,22]]},"reference":[{"issue":"5","key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s12192-016-0704-6","article-title":"Post\u2010exercise cold water immersion does not alter high intensity interval training\u2010induced exercise performance and Hsp72 responses, but enhances mitochondrial markers","volume":"21","author":"Aguiar P. 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