{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T01:21:15Z","timestamp":1789694475473,"version":"4.0.1"},"reference-count":0,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2004,5,4]],"date-time":"2004-05-04T00:00:00Z","timestamp":1083628800000},"content-version":"vor","delay-in-days":976,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Physiology"],"published-print":{"date-parts":[[2001,9]]},"abstract":"<jats:p>The glucagon response to insulin\u2010induced hypoglycaemia was tested in rats that had been pinealectomised (Px), pinealectomised and fitted with melatonin implants (Px + MLT), or sham\u2010operated (SO). The glucagon response to hypoglycaemia observed in SO rats (216 \u00b1 27 pg ml<jats:sup>\u22121<\/jats:sup> at baseline versus 397 \u00b1 35 pg ml<jats:sup>\u22121<\/jats:sup> at the hypoglycaemic peak, mean \u00b1 S.D.) was stronger than that in Px rats (180 \u00b1 37 pg ml<jats:sup>\u22121<\/jats:sup> and 229 \u00b1 21 pg ml<jats:sup>\u22121<\/jats:sup>, respectively) and weaker than that in Px + MLT rats (256 \u00b1 19 pg ml<jats:sup>\u22121<\/jats:sup> and 516 \u00b1 11 pg ml<jats:sup>\u22121<\/jats:sup>, respectively). Our data indicate that the capacity to release glucagon during insulin\u2010induced hypoglycaemia is altered in pinealectomised rats.<\/jats:p>","DOI":"10.1113\/eph8602205","type":"journal-article","created":{"date-parts":[[2003,2,11]],"date-time":"2003-02-11T16:35:06Z","timestamp":1044981306000},"page":"617-620","source":"Crossref","is-referenced-by-count":12,"title":["Effects of Pinealectomy on Glucagon Responsiveness to Hypoglycaemia Induced by Insulin Injections in Fed Rats"],"prefix":"10.1113","volume":"86","author":[{"given":"Erzsebet","family":"Kosa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Maurel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Siaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,5,4]]},"container-title":["Experimental Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Feph8602205","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Feph8602205","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/eph8602205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T14:23:43Z","timestamp":1700403823000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/eph8602205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,9]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,9]]}},"alternative-id":["10.1113\/eph8602205"],"URL":"https:\/\/doi.org\/10.1113\/eph8602205","archive":["Portico"],"relation":{},"ISSN":["0958-0670","1469-445X"],"issn-type":[{"value":"0958-0670","type":"print"},{"value":"1469-445X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,9]]}}}