{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T10:44:32Z","timestamp":1758278672428},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1952,8,16]],"date-time":"1952-08-16T00:00:00Z","timestamp":-548380800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Physiol"],"published-print":{"date-parts":[[1952,8,16]]},"abstract":"<jats:p>1. The endogenous lip\u00e6mia in the rat during the last triempster of pregnancy is briefly described.<\/jats:p><jats:p>2. The visible lip\u00e6mia of pregnancy is abolished by heparin <jats:italic>in vivo<\/jats:italic> but not <jats:italic>in vitro<\/jats:italic>. Decreases of plasma fatty acids in excess of 200 mg. per cent may occur. The decreases also occur in whole blood.<\/jats:p><jats:p>3. These effects of heparin are not obtained with dextran sulphate.<\/jats:p><jats:p>4. Protamine has no effect on the visible lip\u00e6mia, or on the total fatty acid content of the lip\u00e6mic serum.<\/jats:p><jats:p>5. These findings are discussed in relation to the effect of the drugs used on alimentary lip\u00e6mia.<\/jats:p><jats:p>6. Simple proportionality between prolongation of clotting time and fall in lip\u00e6mia does not exist after treatment of the pregnant animals with heparin and dextran sulphate.<\/jats:p><jats:p>7. A heavy precipitate may form in serum, plasma and whole blood drawn from pregnant rats after injection of heparin or dextran sulphate. Its occurrence is not necessarily associated with that of the endogenous lip\u00e6mia. The precipitate contains lipid.<\/jats:p>","DOI":"10.1113\/expphysiol.1952.sp000987","type":"journal-article","created":{"date-parts":[[2014,12,17]],"date-time":"2014-12-17T00:02:50Z","timestamp":1418774570000},"page":"119-129","source":"Crossref","is-referenced-by-count":8,"title":["SOME EFFECTS OF ANTICOAGULANTS AND PROTAMINE ON THE ENDOGENOUS LIP\u00c6MIA OF PREGNANCY"],"prefix":"10.1113","volume":"37","author":[{"given":"W. D.","family":"Brown","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1952,8,16]]},"container-title":["Quarterly Journal of Experimental Physiology and Cognate Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fexpphysiol.1952.sp000987","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/expphysiol.1952.sp000987","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T16:32:39Z","timestamp":1699461159000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/expphysiol.1952.sp000987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1952,8,16]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1952,8,16]]}},"alternative-id":["10.1113\/expphysiol.1952.sp000987"],"URL":"https:\/\/doi.org\/10.1113\/expphysiol.1952.sp000987","archive":["Portico"],"relation":{},"ISSN":["0033-5541"],"issn-type":[{"value":"0033-5541","type":"print"}],"subject":[],"published":{"date-parts":[[1952,8,16]]}}}