{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T20:36:47Z","timestamp":1718656607622},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1969,1,22]],"date-time":"1969-01-22T00:00:00Z","timestamp":-29721600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Physiol"],"published-print":{"date-parts":[[1969,1,22]]},"abstract":"<jats:p>Changes in the ultrastructure of adult rat ventricular muscle induced by <jats:italic>in vitro<\/jats:italic> perfusion with hypokalaemic Krebs\u2010Ringer solutions are described. In all experiments the [Ca<jats:sup>2+<\/jats:sup>] was 1\u00b727 mM.\/l. After perfusion with [K<jats:sup>+<\/jats:sup>]=0, the myofibrils show severe contractures; after [K<jats:sup>+<\/jats:sup>]=1\u00b719 or 2\u00b75 mM.\/l. perfusion, disintegration of the thin filaments was shown; disappearance of myofibrillar insertion plaques at the intercalated discs was observed after perfusion with [K<jats:sup>+<\/jats:sup>] \u2264 1\u00b719; with \u3009 2\u00b75 mM.\/l [K<jats:sup>+<\/jats:sup>], normal ultrastructure was retained.<\/jats:p>","DOI":"10.1113\/expphysiol.1969.sp002002","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T20:07:46Z","timestamp":1418760466000},"page":"36-40","source":"Crossref","is-referenced-by-count":9,"title":["CHANGES IN THE ULTRASTRUCTURE OF RAT MYOCARDIUM INDUCED BY HYPOKALAEMIA"],"prefix":"10.1113","volume":"54","author":[{"given":"J. W.","family":"Emberson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. R.","family":"Muir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1969,1,22]]},"container-title":["Quarterly Journal of Experimental Physiology and Cognate Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fexpphysiol.1969.sp002002","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/expphysiol.1969.sp002002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T16:47:51Z","timestamp":1699462071000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/expphysiol.1969.sp002002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,1,22]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1969,1,22]]}},"alternative-id":["10.1113\/expphysiol.1969.sp002002"],"URL":"https:\/\/doi.org\/10.1113\/expphysiol.1969.sp002002","archive":["Portico"],"relation":{},"ISSN":["0033-5541"],"issn-type":[{"value":"0033-5541","type":"print"}],"subject":[],"published":{"date-parts":[[1969,1,22]]}}}