{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T13:50:37Z","timestamp":1775742637508,"version":"3.50.1"},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1982,10,10]],"date-time":"1982-10-10T00:00:00Z","timestamp":403056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Physiol"],"published-print":{"date-parts":[[1982,10,10]]},"abstract":"<jats:p>Single intravenous injections of bromosulphthalein (BSP) were given to calves before and at intervals after the oral administration of 1000 metacercariae of <jats:italic>Fasciola hepatica<\/jats:italic>. The change in BSP concentration with time was analysed by computer to obtain the proportion of BSP extracted from plasma by hepatic cells (<jats:italic>E<\/jats:italic>) and the rate of hepatic blood flow (<jats:italic>F<\/jats:italic>). The increasing age of the normal calves during the 34 weeks of experiment had no significant effect on <jats:italic>E<\/jats:italic> or <jats:italic>F<\/jats:italic>. There was no significant effect of the duration of the fasciola lesion on <jats:italic>E<\/jats:italic> or <jats:italic>F<\/jats:italic>. When all tests on infected calves were compared as a group with tests on uninfected calves, there was a significant reduction in <jats:italic>E<\/jats:italic>(<jats:italic>P<\/jats:italic> \u3008 0\u00b705) and in <jats:italic>F<\/jats:italic>(<jats:italic>P<\/jats:italic> \u3008 0\u00b7001) in the calves infected with <jats:italic>F. hepatica<\/jats:italic>. A survey of previously reported results suggests that sheep and cattle have a wide range of <jats:italic>F<\/jats:italic> values and that <jats:italic>F<\/jats:italic> is probably lower in 3\u2010month\u2010old calves than in adult cattle.<\/jats:p>","DOI":"10.1113\/expphysiol.1982.sp002671","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T17:40:33Z","timestamp":1418751633000},"page":"513-519","source":"Crossref","is-referenced-by-count":4,"title":["THE USE OF A MODIFIED BROMOSULPHTHALEIN EXCRETION TEST FOR THE MEASUREMENT OF HEPATIC BLOOD FLOW IN CALVES"],"prefix":"10.1113","volume":"67","author":[{"given":"O.","family":"Araya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. J. H.","family":"Ford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1982,10,10]]},"container-title":["Quarterly Journal of Experimental Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fexpphysiol.1982.sp002671","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/expphysiol.1982.sp002671","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T20:46:47Z","timestamp":1699476407000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/expphysiol.1982.sp002671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,10,10]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1982,10,10]]}},"alternative-id":["10.1113\/expphysiol.1982.sp002671"],"URL":"https:\/\/doi.org\/10.1113\/expphysiol.1982.sp002671","archive":["Portico"],"relation":{},"ISSN":["0144-8757"],"issn-type":[{"value":"0144-8757","type":"print"}],"subject":[],"published":{"date-parts":[[1982,10,10]]}}}