{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T12:01:51Z","timestamp":1758628911264},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1985,1,22]],"date-time":"1985-01-22T00:00:00Z","timestamp":475200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Physiol"],"published-print":{"date-parts":[[1985,1,22]]},"abstract":"<jats:p>Plasma K<jats:sup>+<\/jats:sup> and Na<jats:sup>+<\/jats:sup> concentrations ([K<jats:sup>+<\/jats:sup>], [Na<jats:sup>+<\/jats:sup>]), gas tensions (<jats:italic>P<\/jats:italic><jats:sub>O2<\/jats:sub>, <jats:italic>P<\/jats:italic><jats:sub>CO2<\/jats:sub>), pH levels and lactate concentrations ([lactate]) were measured in blood samples obtained before and after applying low\u2010voltage electric shocks (13\u2013130 V a.c., 5\u201350 mA, 50 Hz) from forelimb to opposite hind limb in cats anaesthetized with pentobarbitone. The current intensities used did not induce any changes either in rectal temperature or in the electrocardiogram in post\u2010shock periods. Marked reductions in pH, increases in [K<jats:sup>+<\/jats:sup>] and elevations in [lactate] relative to control values were measured in arterial blood samples following shocks lasting between 10 and 30 s, with the changes in pH and [lactate] more prolonged (45\u201390 min) than the [K<jats:sup>+<\/jats:sup>] alterations (5\u201310 min). Post\u2010shock acidaemia and hyperkalaemia were significantly attenuated by neuromuscular blockade and were more pronounced in samples obtained from blood draining the skinned hind limb than in arterial blood. In the immediate post\u2010shock periods both arterial and venous blood samples showed elevations in <jats:italic>P<\/jats:italic><jats:sub>CO2<\/jats:sub> and decreases in <jats:italic>P<\/jats:italic><jats:sub>O2<\/jats:sub> compared with control levels. No differences in [Na<jats:sup>+<\/jats:sup>] were noted in arterial and venous blood samples obtained before and after shocks. The sequelae of electric shocks noted in this study mainly arose from changes occurring in tetanically contracted muscles during the passage of current and similar residual effects would be expected to be present in human subjects in circumstances where victims of electrical accidents cannot release contact from a low\u2010voltage source. Some of these sequelae may have relevance in explaining the \u2018delayed deaths\u2019 which occasionally follow human electrical accidents.<\/jats:p>","DOI":"10.1113\/expphysiol.1985.sp002882","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T16:29:24Z","timestamp":1418747364000},"page":"101-113","source":"Crossref","is-referenced-by-count":3,"title":["ACIDAEMIA AND HYPERKALAEMIA FOLLOWING LOW\u2010VOLTAGE ELECTRIC SHOCK IN THE ANAESTHETIZED CAT"],"prefix":"10.1113","volume":"70","author":[{"given":"A.","family":"Bradford","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. G.","family":"O'Regan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1985,1,22]]},"container-title":["Quarterly Journal of Experimental Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fexpphysiol.1985.sp002882","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/expphysiol.1985.sp002882","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T19:17:56Z","timestamp":1697829476000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/expphysiol.1985.sp002882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,1,22]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1985,1,22]]}},"alternative-id":["10.1113\/expphysiol.1985.sp002882"],"URL":"https:\/\/doi.org\/10.1113\/expphysiol.1985.sp002882","archive":["Portico"],"relation":{},"ISSN":["0144-8757"],"issn-type":[{"value":"0144-8757","type":"print"}],"subject":[],"published":{"date-parts":[[1985,1,22]]}}}