{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T07:54:34Z","timestamp":1767858874791,"version":"3.49.0"},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1987,10,10]],"date-time":"1987-10-10T00:00:00Z","timestamp":560822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Physiol"],"published-print":{"date-parts":[[1987,10,10]]},"abstract":"<jats:p>Fructose disposal and oxidation rates were measured in fetal lambs receiving a constant intravenous infusion of D\u2010[U\u2010<jats:sup>14<\/jats:sup>C]fructose. Approximately 60% of the infused tracer entered the placenta, but loss of fructose into the maternal circulation was negligible. Fructose was metabolized to lactate and CO<jats:sub>2<\/jats:sub> in both the placenta and fetus, whereas there was no detectable conversion to glucose. In well\u2010fed ewes the fetal disposal and utilization rates of fructose were 2\u00b741\u00b10\u00b717 and 0\u00b797\u00b10\u00b709 mg\/min.kg, respectively. The umbilical excretion rate of CO<jats:sub>2<\/jats:sub> originating from the oxidation of fetal fructose was 18\u00b71\u00b11\u00b73 \u00b5mol\/min.kg or 5\u00b73% of total fetal CO<jats:sub>2<\/jats:sub> production. This excretion rate is one\u2010fifth of the CO<jats:sub>2<\/jats:sub> excretion rate from fetal glucose carbon. In four ewes comparison of fructose metabolism in the fed and fasted states showed a significant decrease of fructose production and oxidation with fasting. Although fructose is present in high concentrations in the fetal blood of ungulates, its contribution to fetal oxidative metabolism is relatively small in comparison to glucose.<\/jats:p>","DOI":"10.1113\/expphysiol.1987.sp003102","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T16:09:06Z","timestamp":1418746146000},"page":"617-625","source":"Crossref","is-referenced-by-count":43,"title":["FRUCTOSE DISPOSAL AND OXIDATION RATES IN THE OVINE FETUS"],"prefix":"10.1113","volume":"72","author":[{"given":"Huei Kang","family":"Meznarich","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"William W.","family":"Hay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John W.","family":"Sparks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Meschia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederick C.","family":"Battaglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1987,10,10]]},"container-title":["Quarterly Journal of Experimental Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fexpphysiol.1987.sp003102","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/expphysiol.1987.sp003102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T12:18:14Z","timestamp":1697890694000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/expphysiol.1987.sp003102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,10,10]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1987,10,10]]}},"alternative-id":["10.1113\/expphysiol.1987.sp003102"],"URL":"https:\/\/doi.org\/10.1113\/expphysiol.1987.sp003102","archive":["Portico"],"relation":{},"ISSN":["0144-8757"],"issn-type":[{"value":"0144-8757","type":"print"}],"subject":[],"published":{"date-parts":[[1987,10,10]]}}}