{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,28]],"date-time":"2025-12-28T02:19:32Z","timestamp":1766888372672},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1989,5,16]],"date-time":"1989-05-16T00:00:00Z","timestamp":611280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Physiol"],"published-print":{"date-parts":[[1989,5,16]]},"abstract":"<jats:p>The concentration of Mg, Na and K in the rumen and plasma of each of four sheep has been studied while test solutions were infused into their jugular veins for 8 h. The experiment was designed as a 4 x 4 Latin square with: treatment 1: diet only; treatment 2: diet +5% dextrose infusion; treatment 3: diet +5% dextrose infusion containing aldosterone; treatment 4: diet +5% dextrose infusion containing aldosterone and potassium canrenoate (a specific inhibitor of the action of aldosterone). Rumen and blood samples were collected every hour during the 8 h treatment period and for the subsequent 4 h. Rumen volume and outflow rate were estimated using an intra\u2010ruminal infusion of [<jats:sup>14<\/jats:sup>C]Cr\u2010EDTA throughout the collection period. The aldosterone infusion significantly (<jats:italic>P<\/jats:italic> \u3008 0\u00b7001) increased the concentration of Mg in the rumen while rumen volume and outflow rate remained unchanged. Plasma concentrations of Mg and K were significantly (<jats:italic>P<\/jats:italic> \u3008 0\u00b7001 and <jats:italic>P<\/jats:italic> \u3008 0\u00b705, respectively) lower during the aldosterone infusion while plasma Na concentrations did not vary significantly. The results are discussed in relation to hypomagnesaemic tetany.<\/jats:p>","DOI":"10.1113\/expphysiol.1989.sp003275","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T15:12:55Z","timestamp":1418742775000},"page":"329-337","source":"Crossref","is-referenced-by-count":15,"title":["THE EFFECT OF AN INTRAVENOUS INFUSION OF ALDOSTERONE UPON MAGNESIUM METABOLISM IN THE SHEEP"],"prefix":"10.1113","volume":"74","author":[{"given":"Judith A.","family":"Charlton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. G.","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1989,5,16]]},"container-title":["Quarterly Journal of Experimental Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fexpphysiol.1989.sp003275","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/expphysiol.1989.sp003275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T15:44:40Z","timestamp":1697989480000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/expphysiol.1989.sp003275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,5,16]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1989,5,16]]}},"alternative-id":["10.1113\/expphysiol.1989.sp003275"],"URL":"https:\/\/doi.org\/10.1113\/expphysiol.1989.sp003275","archive":["Portico"],"relation":{},"ISSN":["0144-8757"],"issn-type":[{"value":"0144-8757","type":"print"}],"subject":[],"published":{"date-parts":[[1989,5,16]]}}}