{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T09:45:19Z","timestamp":1698054319541},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1990,7,1]],"date-time":"1990-07-01T00:00:00Z","timestamp":646790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Physiology"],"published-print":{"date-parts":[[1990,7]]},"abstract":"<jats:p>In anaesthetized dogs, a hindlimb was vascularly isolated and perfused at a constant flow rate of 7.7 +\/\u2010 1.9 ml min\u20101 100 g\u20101 (mean +\/\u2010 S.E.M.; n = 5) through the femoral artery. The carotid sinuses were isolated and perfused at high (greater than 145 mmHg) or low (less than 75 mmHg) pressure to enable reflex sympathetic tone on the hindlimb vessels to be controlled. Both vagi were sectioned in the neck and mean aortic blood pressure was held constant by connection of the aorta to a reservoir. The responses to infusion of three doses of adenosine at high and low carotid sinus pressures were not significantly different: infusion of 0.60 +\/\u2010 0.16 microM\u2010adenosine reduced femoral arterial perfusion pressure (FAPP) by 11.6 +\/\u2010 3.2% (n = 6) at high carotid sinus pressure and by 12.6 +\/\u2010 5.1% (n = 4) at low carotid sinus pressure, while 4.71 +\/\u2010 0.49 microM\u2010adenosine reduced FAPP by 20.8 +\/\u2010 4.8% (n = 6) at high carotid sinus pressure and by 20.7 +\/\u2010 4.8% (n = 6) at low carotid sinus pressure; 50.1 +\/\u2010 7.3 microM\u2010adenosine reduced FAPP by 36.7 +\/\u2010 5.5% (n = 6) at high carotid sinus pressure and by 27.7 +\/\u2010 7.8% (n = 5) at low carotid sinus pressure.(ABSTRACT TRUNCATED AT 250 WORDS)<\/jats:p>","DOI":"10.1113\/expphysiol.1990.sp003426","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T14:54:35Z","timestamp":1418741675000},"page":"497-503","source":"Crossref","is-referenced-by-count":0,"title":["Lack of interaction between adenosine\u2010induced vasodilatation and carotid baroreflex\u2010induced changes in sympathetic activity in dog hindlimb artery"],"prefix":"10.1113","volume":"75","author":[{"given":"HJ","family":"Ballard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Karim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1990,7]]},"container-title":["Experimental Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fexpphysiol.1990.sp003426","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/expphysiol.1990.sp003426","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T17:50:47Z","timestamp":1697997047000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/expphysiol.1990.sp003426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,7]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1990,7]]}},"alternative-id":["10.1113\/expphysiol.1990.sp003426"],"URL":"https:\/\/doi.org\/10.1113\/expphysiol.1990.sp003426","archive":["Portico"],"relation":{},"ISSN":["0958-0670","1469-445X"],"issn-type":[{"value":"0958-0670","type":"print"},{"value":"1469-445X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,7]]}}}