{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T21:25:50Z","timestamp":1763155550330},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,3,7]],"date-time":"2007-03-07T00:00:00Z","timestamp":1173225600000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Physiology"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:p>We designed a conscious pig model to investigate myoelectric activity and the number of interstitial cells of Cajal (ICC) in the proximal jejunum following the Roux\u2010en\u2010Y and \u2018uncut\u2019 Roux procedures in relation to clinical outcomes. Twelve male Polish White pigs (8 weeks old, 10\u201313 kg) underwent surgery under general anaesthesia first to implant bipolar electrodes and telemetry transmitters for continuous electromyography recordings and then, after 1 week recovery, to create Roux\u2010en\u2010Y (<jats:italic>n<\/jats:italic>= 6) and \u2018uncut\u2019 Roux loops (<jats:italic>n<\/jats:italic>= 6). Upper gut tissue specimens were studied for the expression of <jats:italic>c\u2010kit<\/jats:italic> staining procedure to quantitatively identify the presence of interstitial cells of Cajal. The intestinal migrating motor complex was restored within 10.5 and 37 h in \u2018uncut\u2019 Roux and Roux\u2010en\u2010Y pigs, respectively (<jats:italic>P<\/jats:italic> &lt; 0.05). During 2 weeks, the \u2018uncut\u2019 Roux piglets increased their body weight by 18.0%, whereas the Roux\u2010en\u2010Y piglets increased their body weight by only 7.3% (<jats:italic>P<\/jats:italic>\u2264 0.05). Two weeks after surgery, the number of ICC located in the region of Auerbach's plexus was higher and adhesions in the abdominal cavity lower in the \u2018uncut\u2019 Roux group. In conclusion, in the pig model, preservation of smooth muscle and ICC network continuity in the proximal jejunum may play an important role in early postsurgical recovery.<\/jats:p>","DOI":"10.1113\/expphysiol.2006.035253","type":"journal-article","created":{"date-parts":[[2006,12,15]],"date-time":"2006-12-15T01:39:34Z","timestamp":1166146774000},"page":"399-408","source":"Crossref","is-referenced-by-count":14,"title":["Roux\u2010en\u2010Y or \u2018uncut\u2019 Roux procedure? Relation of intestinal migrating motor complex recovery to the preservation of the network of interstitial cells of Cajal in pigs"],"prefix":"10.1113","volume":"92","author":[{"given":"Adam","family":"Kiciak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaros\u0142aw","family":"Woli\u00f1ski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarzyna","family":"Borycka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romuald","family":"Zabielski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krzysztof","family":"Bielecki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,3,7]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"732","article-title":"\u2018Uncut\u2019 Roux 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