{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:27:22Z","timestamp":1793125642548,"version":"4.5.0"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:00:00Z","timestamp":1516320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004794","name":"Centre National de la Recherche Scientifique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec><jats:title>Key points<\/jats:title><jats:p><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>We performed a prospective electrostimulation study, based on 50 operated intact patients, to acquire accurate MNI coordinates of the functional areas of the somatosensory homunculus.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>In the contralateral BA1, the hand representation displayed not only medial\u2010to\u2010lateral, little\u2010finger\u2010to\u2010thumb, but also rostral\u2010to\u2010caudal discrete somatotopy, with the tip of each finger located more caudally than the proximal phalanx.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The analysis of the MNI body coordinates showed rare inter\u2010individual variations in the medial\u2010to\u2010lateral somatotopic organization in these patients with rather different intensity thresholds needed to elicit sensations in different body parts.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>We found some similarities but also substantial differences with the previous, seminal works of Penfield and his colleagues.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>We propose a new drawing of the human somatosensory homunculus according to MNI space.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p>In this prospective electrostimulation study, based on 50 operated patients with no sensory deficit and no brain lesion in the postcentral gyrus, we acquired coordinates in the standard MNI space of the functional areas of the somatosensory homunculus. The 3D brain volume of each patient was normalized to that space to obtain the MNI coordinates of the stimulation site locations. For 647 sites stimulated on Brodmann Area 1 (and 1025 in gyri nearby), 258 positive points for somatosensory response (40%) were found in the postcentral gyrus. In the contralateral BA1, the hand representation displayed not only medial\u2010to\u2010lateral and little\u2010finger\u2010to\u2010thumb somatotopy, but also rostral\u2010to\u2010caudal discrete somatotopy, with the tip of each finger located more caudally than the proximal phalanx. We detected a medial\u2010to\u2010lateral, tip\u2010to\u2010base tongue organization but no rostral\u2010to\u2010caudal functional organization. The analysis of the MNI body coordinates showed rare inter\u2010individual variations in the medial\u2010to\u2010lateral somatotopic organization in these patients with intact somatosensory cortex. Positive stimulations were detected through the \u2018on\/off\u2019 outbreak effect and discriminative touch sensations were the sensations reported almost exclusively by all patients during stimulation. Mean hand (2.39\u00a0mA) and tongue (2.60\u00a0mA) positive intensity thresholds were lower (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05) than the intensities required to elicit sensations in the other parts of the body. Unlike the previous, seminal works of Penfield and colleagues, we detected no sensations such as sense of movement or desire to move, no somatosensory responses outside the postcentral gyrus, and no bilateral responses for face\/tongue stimulations. We propose a rationalization of the standard drawing of the somatosensory homunculus according to MNI space.<\/jats:p><\/jats:sec>","DOI":"10.1113\/jp275243","type":"journal-article","created":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T05:22:39Z","timestamp":1514524959000},"page":"941-956","source":"Crossref","is-referenced-by-count":165,"title":["Functional architecture of the somatosensory homunculus detected by electrostimulation"],"prefix":"10.1113","volume":"596","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4209-7117","authenticated-orcid":false,"given":"Franck\u2010Emmanuel","family":"Roux","sequence":"first","affiliation":[{"name":"CNRS (CERCO) UMR Unit\u00e9 5549 Universit\u00e9 Paul Sabatier  Toulouse 31059 France"},{"name":"P\u00f4le NeuroSciences (Neurochirurgie) Centres Hospitalo\u2010Universitaires  Toulouse 31059 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