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This is to our knowledge the first study investigating the human cerebellar electrophysiology using optically pumped magnetometers. As a proof of principle, we use an air\u2010puff stimulus to the eyeball in order to elicit cerebellar activity that is well characterized in non\u2010human models. In three subjects, we observe an evoked component at approx. 50\u00a0ms post\u2010stimulus, followed by a second component at approx. 85\u2013115\u00a0ms post\u2010stimulus. Source inversion localizes both components in the cerebellum, while control experiments exclude potential sources elsewhere. We also assess the induced oscillations, with time\u2010frequency decompositions, and identify additional sources in the occipital lobe, a region expected to be active in our paradigm, and in the neck muscles. Neither of these contributes to the stimulus\u2010evoked responses at 50\u2013115\u00a0ms. We conclude that OP\u2010MEG technology offers a promising way to advance the understanding of the information processing mechanisms in the human cerebellum.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1113\/jp277899","type":"journal-article","created":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T21:38:26Z","timestamp":1561498706000},"page":"4309-4324","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Using optically pumped magnetometers to measure magnetoencephalographic signals in the human cerebellum"],"prefix":"10.1113","volume":"597","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2156-1830","authenticated-orcid":false,"given":"Chin\u2010Hsuan","family":"Lin","sequence":"first","affiliation":[{"name":"Wellcome Centre for Human Neuroimaging Queen Square Institute of Neurology University College London  London UK"},{"name":"School of Psychology University of Birmingham  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim M.","family":"Tierney","sequence":"additional","affiliation":[{"name":"Wellcome Centre for Human Neuroimaging Queen Square Institute of Neurology University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niall","family":"Holmes","sequence":"additional","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre School of Physics and Astronomy University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Boto","sequence":"additional","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre School of Physics and Astronomy University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Leggett","sequence":"additional","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre School of Physics and Astronomy University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Bestmann","sequence":"additional","affiliation":[{"name":"Wellcome Centre for Human Neuroimaging Queen Square Institute of Neurology University College London  London UK"},{"name":"Department of Clinical and Movement Neuroscience Queen Square Institute of Neurology University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Bowtell","sequence":"additional","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre School of Physics and Astronomy University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Brookes","sequence":"additional","affiliation":[{"name":"Sir Peter Mansfield Imaging Centre School of Physics and Astronomy University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gareth R.","family":"Barnes","sequence":"additional","affiliation":[{"name":"Wellcome Centre for Human Neuroimaging Queen Square Institute of Neurology University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. 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