{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T13:46:31Z","timestamp":1792158391616,"version":"4.4.0"},"reference-count":95,"publisher":"Wiley","issue":"20","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>\n                      The Developmental Origins of Health and Disease framework proposes that adverse exposures during critical developmental windows induce epigenetic programming, increasing lifelong risk of metabolic and organ dysfunction. Maternal protein restriction (MPR) is a well\u2010established model of early\u2010life nutritional stress, associated with reduced nephron number early in life, in addition to renal dysfunction and hypertension during adult life. However, its long\u2010term impact on renal ageing remains unclear. This study investigated the effects of gestational and lactational severe MPR (6% compared to 17% in controls) on the renal proteome of aged male Sprague\u2013Dawley rats (postnatal day 540) using integrated histological, molecular and\n                      <jats:italic>in silico<\/jats:italic>\n                      approaches. MPR induced persistent renal impairment, evidenced by increased serum creatinine and tubular congestion. Proteomic analysis revealed upregulation of proteins related to small\u2010molecule transport, stress response and energy metabolism, particularly within mitochondrial and redox pathways. By contrast, downregulated pathways involved cytoskeletal organization, vesicular transport, immune processes and post\u2010transcriptional regulation, suggesting disruption of endomembrane dynamics. Pathway enrichment highlighted central metabolic networks, including glycolysis, pyruvate metabolism and the tricarboxylic acid cycle. Network and microRNA analyses indicated epigenetic regulation, whereas disease enrichment linked findings to metabolic and renal disorders. Nephron\u2010segment mapping revealed region\u2010specific alterations. Overall, MPR induces persistent renal programming, disrupting metabolism and function and increasing susceptibility to renal and metabolic diseases with ageing.\n                      <jats:boxed-text content-type=\"graphic\" position=\"anchor\">\n                        <jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/tjp70786-gra-0001-m.png\">\n                          <jats:alt-text>image<\/jats:alt-text>\n                        <\/jats:graphic>\n                      <\/jats:boxed-text>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Maternal protein restriction (MPR) shifts renal proteome to mitochondrial\/redox metabolism.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>MPR causes renal histopathological lesions during ageing.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>The impacts of MPR are reflected in cellular and molecular alterations indicative of potential renal dysfunction.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Nephron\u2010specific and epigenetic alterations indicate targeted functional disruption.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Persistent changes link early malnutrition to renal and metabolic disease risk.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1113\/jp291758","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:40:21Z","timestamp":1788201621000},"page":"8636-8661","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Maternal protein restriction programs the ageing kidney: Proteomic signatures of early\u2010life origin renal and metabolic dysfunction"],"prefix":"10.1113","volume":"604","author":[{"given":"Marina Pereira","family":"Pires","sequence":"first","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0138-7959","authenticated-orcid":false,"given":"Matheus Naia","family":"Fioretto","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel Rodrigues","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Molecular Genetics and Bioinformatics Laboratory, Experimental Research Unit\u00a0\u2013\u00a0Unipex, School of Medicine S\u00e3o Paulo State University\u00a0\u2013\u00a0Unesp  Botucatu S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1771-0984","authenticated-orcid":false,"given":"Isabelle Tenori","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu\u00edsa Annibal","family":"Barata","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fl\u00e1via Alessandra","family":"Maciel","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1881-7820","authenticated-orcid":false,"given":"Lucas Sobrinho","family":"Lemos","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato","family":"Mattos","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Marcos Frediane","family":"Portela","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick Vieira de","family":"Souza","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa Correia","family":"Gomes","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo Monezzi","family":"Cordeiro","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wellerson Rodrigo","family":"Scarano","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"},{"name":"Brazilian National Institute of Science and Technology in DOHaD Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1196-2606","authenticated-orcid":false,"given":"Patr\u00edcia Aline","family":"Boer","sequence":"additional","affiliation":[{"name":"Brazilian National Institute of Science and Technology in DOHaD Brazil"},{"name":"Fetal Programming and Hydroelectrolyte Metabolism Laboratory, Nucleus of Medicine and Experimental Surgery, Department of Internal Medicine, FCM Campinas State University (UNICAMP)  Campinas S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Antonio Rocha","family":"Gontijo","sequence":"additional","affiliation":[{"name":"Brazilian National Institute of Science and Technology in DOHaD Brazil"},{"name":"Fetal Programming and Hydroelectrolyte Metabolism Laboratory, Nucleus of Medicine and Experimental Surgery, Department of Internal Medicine, FCM Campinas State University (UNICAMP)  Campinas S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6142-3515","authenticated-orcid":false,"given":"Luis Antonio","family":"Justulin","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Biology, Institute of Biosciences Sao Paulo State University  Botucatu S\u00e3o Paulo Brazil"},{"name":"Brazilian National Institute of Science and Technology in DOHaD Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.09.010"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13105-026-01189-9"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000317739"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0210454"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0221686"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.298.6673.564"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)91224-A"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2004.tb00236.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(76)90527-3"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab447"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15163616"},{"key":"e_1_2_6_13_1","first-page":"128","article-title":"Enrichr: Interactive and collaborative HTML5 gene list enrichment analysis tool","volume":"14","author":"Chen E. Y.","year":"2013","journal-title":"BioMed Central Bioinformatics"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32977-0"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2011.368"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.663216"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-023-00655-4"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom12101415"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.1857"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/cimb44060169"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2025.111707"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00356.2019"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.122929"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btz931"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0266293"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu393"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw313"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2020.118276"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00029.2013"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114508057607"},{"issue":"4","key":"e_1_2_6_31_1","first-page":"1539","article-title":"miR\u201130a\u20115p inhibits hypoxia\/reoxygenation\u2011induced oxidative stress and apoptosis in HK\u20112 renal tubular epithelial cells by targeting glutamate dehydrogenase 1 (GLUD1)","volume":"44","author":"He Y.","year":"2020","journal-title":"Oncology Reports"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00079.2006"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.839436"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1089\/dna.2020.5453"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41440-020-0451-z"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa970"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00150.2019"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw377"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s100380170057"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.658431"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.23766"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btt285"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2014.251"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202502544RR"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.03218"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu17040651"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfp505"},{"key":"e_1_2_6_48_1","unstructured":"Morgan M. Falcon S. &Gentleman R.(2021).GSEABase: Gene set enrichment data structures and methods. R package version 1.56.0."},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1017\/S2040174412000463"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2024.112348"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkae253"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1139\/apnm-2018-0288"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00062.2024"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2019.10.005"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197608122950701"},{"key":"e_1_2_6_56_1","unstructured":"R Core Team. (2022).R: A language and environment for statistical computing.R Foundation for Statistical Computing https:\/\/www.R\u2010project.org\/"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/123.11.1939"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2017111179"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2022.01.014"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2025.167827"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/gly118"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1159\/000094538"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-024-01356-x"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2016-1167"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071310"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.171694"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0246289"},{"key":"e_1_2_6_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-015-3169-4"},{"key":"e_1_2_6_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.14555"},{"key":"e_1_2_6_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2025.114795"},{"key":"e_1_2_6_71_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.205083"},{"key":"e_1_2_6_72_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines14010184"},{"key":"e_1_2_6_73_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0206239"},{"key":"e_1_2_6_74_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku1003"},{"key":"e_1_2_6_75_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjdrc-2024-004854"},{"key":"e_1_2_6_76_1","unstructured":"The ISN. (2025).Historic win for kidney health as WHO adopts global resolution.The International Society of Nephrology. Retrieved September 18 2025 fromhttps:\/\/www.theisn.org\/blog\/2025\/05\/23\/historic\u2010win\u2010for\u2010kidney\u2010health\u2010as\u2010who\u2010adopts\u2010global\u2010resolution\/"},{"issue":"6","key":"e_1_2_6_77_1","first-page":"1614","article-title":"Of mice and men: The effect of maternal protein restriction on offspring's kidney health. Are studies on rodents applicable to chronic kidney disease patients?","volume":"12","author":"Torreggiani M.","year":"2020","journal-title":"A Narrative Review Nutrients"},{"key":"e_1_2_6_78_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-022-00997-y"},{"key":"e_1_2_6_79_1","doi-asserted-by":"publisher","DOI":"10.1017\/S2040174420000276"},{"key":"e_1_2_6_80_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00108.2020"},{"key":"e_1_2_6_81_1","doi-asserted-by":"publisher","DOI":"10.1089\/omi.2011.0118"},{"key":"e_1_2_6_82_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2023.1156029"},{"key":"e_1_2_6_83_1","doi-asserted-by":"publisher","DOI":"10.1159\/000546897"},{"key":"e_1_2_6_84_1","doi-asserted-by":"publisher","DOI":"10.21105\/joss.01686"},{"key":"e_1_2_6_85_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-200104000-00005"},{"issue":"3","key":"e_1_2_6_86_1","article-title":"clusterProfiler 4.0: A universal enrichment tool for interpreting omics data","volume":"2","author":"Wu T.","year":"2021","journal-title":"Innovation"},{"key":"e_1_2_6_87_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/6978984"},{"key":"e_1_2_6_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/cpz1.90"},{"key":"e_1_2_6_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2024.110175"},{"key":"e_1_2_6_90_1","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2019.1669460"},{"key":"e_1_2_6_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2025.152339"},{"key":"e_1_2_6_92_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202300865R"},{"key":"e_1_2_6_93_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.690697"},{"key":"e_1_2_6_94_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-47504-x"},{"key":"e_1_2_6_95_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c7065"},{"key":"e_1_2_6_96_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10863-024-10027-w"}],"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/JP291758","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/full-xml\/10.1113\/JP291758","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/JP291758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T12:53:31Z","timestamp":1792155211000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/JP291758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":95,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1113\/JP291758"],"URL":"https:\/\/doi.org\/10.1113\/jp291758","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,31]]},"assertion":[{"value":"2026-05-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}