{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T02:38:16Z","timestamp":1777430296170,"version":"3.51.4"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1966,11,1]],"date-time":"1966-11-01T00:00:00Z","timestamp":-99964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1966,11]]},"abstract":"<jats:p>1. Membrane potentials and resistances of K\u2010depleted muscles were measured in the cold and again after warming in K\u2010containing media so that active ion movements occurred.<\/jats:p><jats:p>2. On warming there was a fall of resistance and a gradual rise of potential which passed through a maximum. Later measurements of resistance in a chloride medium showed that values were, if anything, higher than initially in the warm.<\/jats:p><jats:p>3. The excess potentials measured approximated to those required to induce passive inward movement of the K ions through the measured K resistance.<\/jats:p><jats:p>4. Permeabilities for K<jats:sup>+<\/jats:sup> and Cl<jats:sup>\u2212<\/jats:sup> were deduced. When cocaine, procaine, amytal or mepyramine were added or when K<jats:sup>+<\/jats:sup> was replaced by Rb<jats:sup>+<\/jats:sup> in the Cl<jats:sup>\u2212<\/jats:sup>\u2010free solution the K<jats:sup>+<\/jats:sup> permeability was eventually reduced. The same agents led to an enhanced initial response of potential to warming, but later the potentials in Cl<jats:sup>\u2212<\/jats:sup>\u2010free media fell to less than the K<jats:sup>+<\/jats:sup> equilibrium values.<\/jats:p><jats:p>5. A method for obtaining the resistivity of the membrane from measurements made in conditions of non\u2010linear voltage\u2014current dependence was applied.<\/jats:p>","DOI":"10.1113\/jphysiol.1966.sp008072","type":"journal-article","created":{"date-parts":[[2014,12,20]],"date-time":"2014-12-20T02:35:07Z","timestamp":1419042907000},"page":"5-21","source":"Crossref","is-referenced-by-count":15,"title":["Effects of sodium extrusion and local anaesthetics on muscle membrane resistance and potential"],"prefix":"10.1113","volume":"187","author":[{"given":"E. J.","family":"Harris","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ochs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1966,11]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1966.sp008072","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1966.sp008072","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T12:01:47Z","timestamp":1699444907000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1966.sp008072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1966,11]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1966,11]]}},"alternative-id":["10.1113\/jphysiol.1966.sp008072"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1966.sp008072","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1966,11]]}}}