{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T03:08:52Z","timestamp":1771643332471,"version":"3.50.1"},"reference-count":0,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[1968,2,1]],"date-time":"1968-02-01T00:00:00Z","timestamp":-60480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Physiology"],"published-print":{"date-parts":[[1968,2]]},"abstract":"<jats:p>1. The development of fatigue in isolated toad sartorius undergoing short, periodic, isometric tetani of controlled duration, was studied. Stimulation was direct and curare was used.<\/jats:p><jats:p>2. In the great majority of cases extratension decreased very regularly towards a steady value, following a simple exponential equation.<\/jats:p><jats:p>3. The final steady tension (expressed as percentage of the maximum) and the constant of exponential decay varied as simple functions of the mean frequency of stimulation and their product was a constant.<\/jats:p>","DOI":"10.1113\/jphysiol.1968.sp008408","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T12:09:53Z","timestamp":1418990993000},"page":"289-303","source":"Crossref","is-referenced-by-count":3,"title":["The evolution of fatigue associated with isometric contraction in toad sartorius"],"prefix":"10.1113","volume":"194","author":[{"given":"Emilio F.","family":"Aljure","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis M.","family":"Borrero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1968,2]]},"container-title":["The Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1113%2Fjphysiol.1968.sp008408","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.1113\/jphysiol.1968.sp008408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T18:49:27Z","timestamp":1699469367000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.1113\/jphysiol.1968.sp008408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1968,2]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1968,2]]}},"alternative-id":["10.1113\/jphysiol.1968.sp008408"],"URL":"https:\/\/doi.org\/10.1113\/jphysiol.1968.sp008408","archive":["Portico"],"relation":{},"ISSN":["0022-3751","1469-7793"],"issn-type":[{"value":"0022-3751","type":"print"},{"value":"1469-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[1968,2]]}}}